Results 1 to 10 of about 311,985 (405)

Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2

Nature Communications, 2016
In chronic kidney disease (CKD), proteinuria results in severe tubulointerstitial lesions, which ultimately lead to end-stage renal disease. Here we identify 4-phenylbutyric acid (PBA), a chemical chaperone already used in humans, as a novel therapeutic ...
K. El Karoui, Amandine Viau, O. Dellis, A. Bagattin, Clément Nguyen, William Baron, M. Burtin, Mélanie Broueilh, L. Heidet, G. Mollet, A. Druilhe, C. Antignac, B. Knebelmann, G. Friedlander, F. Bienaimé, Morgan Gallazzini, F. Terzi   +16 more
semanticscholar   +1 more source

Provision of medical supply kits to improve quality of antenatal care in Mozambique: a stepped-wedge cluster randomised trial [PDF]

, 2018
Background High levels of maternal and newborn mortality and morbidity remain a daunting reality in many low-income countries. Several interventions delivered during antenatal care have been shown to improve maternal and newborn outcomes, but stockouts ...
Aleman, Alicia, Althabe, Fernando, Bergel, Eduardo, Betrán, Ana Pilar, Biza, Adriano, Carbonell, Alicia, Chavane, Leonardo, Colomar, Mercedes, Crahay, Beatrice, Delvaux, Therese, Dique Ali, Ussumane, Fersurela, Lucio, Geelhoed, Diederike, Griffin, Sally, Gülmezoglu, A Metin, Jille-Taas, Ingeborg, Langa, Célio, Malapende, Celsa Regina, Melo, Armando, Merialdi, Mario, Mondlane, Santos, Nguyen, My Huong, Osman, Nafissa Bique, Requejo, Jennifer, Temmerman, Marleen, Timbe, Geraldo   +25 more
core   +1 more source

Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]

, 2014
Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G., Freel, E. Marie, Jardine, Alan G., Mark, Patrick, McQuarrie, Emily P., Taylor, Alison H., Traynor, Jamie P.   +6 more
core   +1 more source

Seasonal relapsing minimal change disease: a novel strategy for avoiding long-term immunosuppression. [PDF]

, 2012
BACKGROUND: We describe the case of a young woman with seasonal allergic rhinitis who presented with signs of a lower respiratory tract infection, acute renal impairment and the nephrotic syndrome, demonstrated on biopsy to be due to minimal change ...
Cook, HT, Lawrence, C, Lightstone, L
core   +2 more sources

Proteinuria in Dent disease: a review of the literature

Pediatric nephrology (Berlin, West), 2016
BackgroundDent disease is a rare X-linked recessive proximal tubulopathy caused by mutations in CLCN5 (Dent-1) or OCRL (Dent-2). As a rule, total protein excretion (TPE) is low in tubular proteinuria compared with glomerular disease. Several authors have
Y. Van Berkel, M. Ludwig, Joanna A.E. van Wijk, A. Bökenkamp   +3 more
semanticscholar   +1 more source

Prevalence of and Risk Factors for Paroxysmal Atrial Fibrillation in Patients with Cardiovascular Disease but without diagnosed Atrial Fibrillation [PDF]

, 2019
学位記番号 ...
Niijima, Katsura, ニイジマ, カツラ, 新島, 桂   +2 more
core  

Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B-2 kinin receptors [PDF]

, 2002
Background/Aim: Patients with idiopathic focal segmental glomerulosclerosis (FSGS) often develop a recurrence of the disease after kidney transplantation.
Fink, E., Fischer, K. G., Henger, A., Huber, T. B., Pavenstadt, H., Rump, L. C., Schwertfeger, E.   +6 more
core   +1 more source

Proteinuria in frasier syndrome

Srpski arhiv za celokupno lekarstvo, 2013
Introduction. Frasier syndrome (FS) is a genetic form of glomerulopathy, which results from mutations in the Wilms? tumour suppressor gene (WT1). Proteinuria in FS has been traditionally considered unresponsive to any medication and FS inevitably progresses to end stage renal failure. Case Outline.
Peco-Antic, Amira, Ozaltin, Fatih, Parezanovic, Vojislav, Milosevski-Lomic, Gordana, Zdravkovic, Verica   +4 more
openaire   +4 more sources

For the eye altering, alters the all [PDF]

, 2015
C
Boey, Olivier, Bogaert, Anne-Marie, De Scheerder, Marie-Angélique, Mahieu, Elien, Vanuytsel, Johan   +4 more
core   +1 more source

Risk factors of proteinuria in renal cell carcinoma patients treated with VEGF inhibitors: a secondary analysis of pooled clinical trial data

British Journal of Cancer, 2016
Background:Proteinuria is a common adverse effect of vascular endothelial growth factor targeted agents, particularly in metastatic renal cell carcinoma (mRCC).
M. Sorich, A. Rowland, G. Kichenadasse, R. Woodman, A. Mangoni   +4 more
semanticscholar   +1 more source