Results 41 to 50 of about 311,985 (405)

Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling

Nature Communications, 2017
Podocyte injury is a major determinant of proteinuric kidney disease and the identification of potential therapeutic targets for preventing podocyte injury has clinical importance.
Min Liu, Kaili Liang, J. Zhen, Meng Zhou, Xiaojie Wang, Ziying Wang, Xinbing Wei, Yan Zhang, Yu Sun, Zhuanli Zhou, H. Su, Chun Zhang, Ningjun Li, Chengjiang Gao, J. Peng, F. Yi   +15 more
semanticscholar   +1 more source

Low-Grade Proteinuria Does Not Exclude Significant Kidney Injury in Lupus Nephritis

Kidney International Reports, 2020
K idney involvement is common in systemic lupus erythematosus (SLE) and is a major cause of morbidity and mortality. About 50% to 70% of adults and 37% to 82% of children with SLE develop lupus nephritis (LN).
M. De Rosa, A. S. Rocha, G. De Rosa, Diana Dubinsky, S. Almaani, B. Rovin   +5 more
semanticscholar   +1 more source

Changes in Proteinuria on the Risk of All-Cause Mortality in People with Diabetes or Prediabetes: A Prospective Cohort Study

Journal of Diabetes Research, 2017
Background. Proteinuria has been related to all-cause mortality, showing regression or progression. However, few studies have focused on the relationship between proteinuria changes and all-cause mortality.
Yang Sun, Anxin Wang, Xiaoxue Liu, Zhaoping Su, Junjuan Li, Yanxia Luo, Shuohua Chen, Jianli Wang, Xia Li, Zhan Zhao, Huiping Zhu, Shouling Wu, Xiuhua Guo   +12 more
doaj   +1 more source

Preoperative proteinuria is associated with long-term progression to chronic dialysis and mortality after coronary artery bypass grafting surgery. [PDF]

PLoS ONE, 2012
AIMS: Preoperative proteinuria is associated with post-operative acute kidney injury (AKI), but whether it is also associated with increased long-term mortality and end-stage renal disease (ESRD) is unknown.
Vin-Cent Wu, Tao-Min Huang, Pei-Chen Wu, Wei-Jie Wang, Chia-Ter Chao, Shao-Yu Yang, Chih-Chung Shiao, Fu-Chang Hu, Chun-Fu Lai, Yu-Feng Lin, Yin-Yi Han, Yih-Sharng Chen, Ron-Bin Hsu, Guang-Huar Young, Shoei-Shen Wang, Pi-Ru Tsai, Yung-Ming Chen, Ting-Ting Chao, Wen-Je Ko, Kwan-Dun Wu, NSARF Group   +20 more
doaj   +1 more source

Clinical and pathologic characteristics of pauci-immune anti-myeloperoxidase antibody associated glomerulonephritis with nephrotic range proteinuria

Renal Failure, 2018
Background: Heavy proteinuria in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis (GN) is usually considered to be associated with immune deposits in renal biopsy.
Peng-Cheng Xu, Tong Chen, Shan Gao, Shui-Yi Hu, Li Wei, Tie-Kun Yan   +5 more
doaj   +1 more source

Nonalbumin Proteinuria in Islet Transplant Recipients

Cell Transplantation, 2010
The aim of this study was to evaluate the importance of nonalbumin-predominant proteinuria on kidney function (KF) after islet transplantation (ITx). Twenty-four-hour proteinuria and albuminuria were available in 27 recipients.
Cristiane B. Leitão, Tatiana Froud, Pablo Cure, Thipaporn Tharavanij, Antonello Pileggi, Camillo Ricordi, Rodolfo Alejandro   +6 more
doaj   +1 more source

Antiproteinuric action of amiloride in paediatric patient with corticoresistant nephrotic syndrome

Nefrología (English Edition), 2021
Introduccion: In nephrotic syndrome, increased podocyturia accompanies pathologic proteinuria. The therapeutic regimen with enalapril, losartan and amiloride could reduce both variables.
Miguel Liern, Anabella Colazo, Graciela Vallejo, Elsa Zotta   +3 more
doaj   +1 more source

Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus [PDF]

, 2015
Introduction ES-62, a phosphorylcholine (PC)-containing immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, protects against nephritis in the MRL/Lpr mouse model of systemic lupus erythematosus (SLE).
Harnett, M. M., Harnett, W., Pineda, M. A., Rodgers, D. T., Suckling, C. J.   +4 more
core   +1 more source

Pathophysiology of proteinuria [PDF]

Kidney International, 2003
Proteinuria is consequence of two mechanisms: the abnormal transglomerular passage of proteins due to increased permeability of glomerular capillary wall and their subsequent impaired reabsorption by the epithelial cells of the proximal tubuli. In the various glomerular diseases, the severity of disruption of the structural integrity of the glomerular ...
D'Amico, Giuseppe, Bazzi, Claudio
openaire   +3 more sources

Acute kidney injury in the elderly: predisposition to chronic kidney disease and vice versa. [PDF]

, 2011
There have been considerable advances in the past few years in our understanding of how chronic kidney disease (CKD) predisposes to acute kidney injury (AKI) and vice versa.
Cho, Kerry C, Coca, Steven G, Hsu, Chi-yuan   +2 more
core   +2 more sources