Results 21 to 30 of about 311,985 (405)

Clinical Outcomes of Patients With Primary Membranous Nephropathy and Subnephrotic Proteinuria

Frontiers in Medicine, 2021
Objectives: To update the information about the prognosis of patients with primary membranous nephropathy (MN) and subnephrotic proteinuria and identify the relevant predictors.Methods: In total, 474 cases of biopsy-proven primary MN with at least 18 ...
Peng He, Yang Zha, Jing Liu, Hanmin Wang, Lijie He   +4 more
doaj   +1 more source

New insight into podocyte slit diaphragm, a therapeutic target of proteinuria

Clinical and Experimental Nephrology, 2020
Dysfunction of slit diaphragm, a cell–cell junction of glomerular podocytes, is involved in the development of proteinuria in several glomerular diseases. Slit diaphragm should be a target of a novel therapy for proteinuria.
H. Kawachi, Y. Fukusumi
semanticscholar   +1 more source

Clinical Approach to Children with Proteinuria [PDF]

Childhood Kidney Diseases, 2017
Proteinuria is common in pediatric and adolescent patients. Proteinuria is defined as urinary protein excretion at levels higher than 100-150 mg/m2/day in children.
Kyung Mi Jang, Min Hyun Cho
doaj   +1 more source

Sex differences in the evaluation of proteinuria using the urine dipstick test

Frontiers in Medicine, 2023
BackgroundThe urine protein dipstick test is widely used, but false-positive and false-negative results may occur. This study aimed to compare the urine protein dipstick test with a urine protein quantification method.MethodsThe data were extracted using
Chiari Kojima, Chiari Kojima, Hiroshi Umemura, Tatsuo Shimosawa, Tomohiro Nakayama   +4 more
doaj   +1 more source

Low-grade proteinuria and atherosclerotic cardiovascular disease: A transition study of patients with diabetic kidney disease.

PLoS ONE, 2022
Diabetic kidney disease (DKD) is heterogeneous in terms of proteinuria. Patients with DKD who present with low-grade proteinuria are more likely to have nephrosclerosis rather than traditional diabetic nephropathy. The amount of proteinuria might reflect
Satoshi Yamaguchi, Takayuki Hamano, Tatsufumi Oka, Yohei Doi, Sachio Kajimoto, Yusuke Sakaguchi, Akira Suzuki, Yoshitaka Isaka   +7 more
doaj   +1 more source

Noninvasive Urinary Monitoring of Progression in IgA Nephropathy. [PDF]

, 2019
Standard methods for detecting and monitoring of IgA nephropathy (IgAN) have conventionally required kidney biopsies or suffer from poor sensitivity and specificity.
Fervenza, Fernando C, Lafayette, Richard A, Sarwal, Minnie M, Sarwal, Reuben D, Yang, Joshua YC   +4 more
core   +1 more source

Pilot trial of fk 506 in the management of steroid-resistant nephrotic syndrome [PDF]

, 1993
Seven patients with steroid-resistant nephrotic syndrome were treated with FK 506 monotherapy. Four patients were children with focal sclerosing glomerulonephritis (FSGS).
Ellis, D, Igdal, H, McCalley, J, Shapiro, R, Shapiro, R, Starzl, TE, Starzl, TE, Starzl, TE, Tzakis, A, Tzakis, A   +9 more
core   +1 more source

Renal AA-amyloidosis in intravenous drug users - a role for HIV-infection? [PDF]

, 2012
Background: Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.
Amann, Kerstin Ute, Betz, Christoph, Bickel, Markus, Büttner, Maike, Grützmacher, Peter, Haack, Hans Stefan, Jung, Oliver, Stephan, Christoph   +7 more
core   +2 more sources

Proteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy.

American Society of Nephrology. Clinical Journal, 2019
IgA nephropathy (IgAN) is an important cause of ESKD for which there are no approved therapies. A challenge for evaluating treatments for IgAN is the usual long time course for progression to ESKD.
A. Thompson, K. Carroll, Lesley A Inker, J. Floege, V. Perkovic, Sonia Boyer-Suavet, Rupert W Major, Judith I Schimpf, J. Barratt, D. Cattran, Barbara S Gillespie, A. Kausz, Alex W Mercer, H. Reich, Brad H. Rovin, Melissa West, P. Nachman   +16 more
semanticscholar   +1 more source

Quantifying Duration of Proteinuria Remission and Association with Clinical Outcome in IgA Nephropathy.

Journal of the American Society of Nephrology, 2020
BACKGROUND On the basis of findings of observational studies and a meta-analysis, proteinuria reduction has been proposed as a surrogate outcome in IgA nephropathy. How long a reduction in proteinuria needs to be maintained to mitigate the long-term risk
M. Canney, S. Barbour, Yuyan Zheng, R. Coppo, Hong Zhang, Zhi-Hong Liu, K. Matsuzaki, Yusuke Suzuki, R. Katafuchi, H. Reich, D. Cattran   +10 more
semanticscholar   +1 more source