Results 171 to 180 of about 120,733 (325)

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou, Yu Wu, Guoran Li, Yongwen Qin, Man Qi, Zhitao Jin   +5 more
wiley   +1 more source

Association between cardiometabolic index and albuminuria: Evidence from NHANES 2017-2020.

PLoS ONE
IntroductionAlbuminuria is a crucial marker of kidney damage and serves as an early indicator of the risk for chronic kidney disease (CKD). Recent studies have suggested that the cardiometabolic index (CMI), could be valuable for screening renal ...
Qiming Xu, Junyan Lin, Lin Liao, Jing Hu, Jianrao Lu   +4 more
doaj   +1 more source

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source

Albuminuria with Convulsions [PDF]

BMJ, 1870
W, Dobie, J, Ramsay
openaire   +2 more sources

The Indonesia pre‐eclampsia study (INAPRES): Pregnancy outcomes in pregnancy with pre‐eclampsia in Indonesia

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aimed to investigate maternal and neonatal outcomes of pregnancies complicated by pre‐eclampsia (PE) in Indonesia and analyze regional variations in risk factors and clinical outcomes across the country. Methods A multicenter retrospective cohort study was conducted in 30 hospitals located across five major islands in ...
Muhammad Ilham Aldika Akbar, Khanisyah Erza Gumilar, Adhi Pribadi, Muhammad Alamsyah Aziz, Ernawati Ernawati, Manggala Pasca Wardhana, Agus Sulistyono, Muhammad Adrianes Bachnas, Rima Irwinda, Bambang Rahardjo, Aditiawarman, Agus Rusdhy Hariawan Hamid, Julian Dewantiningrum, Fransiscus Octavianus Hari Prasetyadi, Febriansyah Darus, Ariawan Ditya, Jonathan Kevin Djuanda, Ruth Widhiati Raharjo Putri, Tedy Teguh Satriadi, Alini Hafiz, Roza Sriyanti, Dovy Djanas, A. I. Suratman, Aryani Aziz, Novi Resistantie, Ario Danianto, Yuyun Lisnawati, Purnawan Senoaji, Sri Pudyastuti, Besari Adi Pramono, Dharma Putra P. Banjarnahor, Dhanny Primatara Johari Santoso, Defrin Defrin, Junneke J. Kaeng, Nutria Widya Purna Anggraini, Anak Agung Gede Putra Wiradyana, Anak Agung Ngurah Jaya Kusuma, Nuswil Bernolian, Joserizal Serudji, Cut Meurah Yeni, Maisuri T. Chalid, Yusrawati, John J. E. Wantania, Sarma Lumbanraja, Sri Sulistyowati, Noroyono Wibowo, Johanes C. Mose, Erry Gumilar Dachlan, Gustaaf Dekker, Rozi Aditya Aryananda   +49 more
wiley   +1 more source

Diagnostic performance of urinary adipsin as a screening biomarker for pre‐eclampsia

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluated the diagnostic performance of urinary adipsin as a potential biomarker for pre‐eclampsia screening in a low‐resource setting. Methods A case–control study was conducted involving 150 pregnant women classified into three groups: 50 healthy pregnancies, 50 high‐risk pregnancies without pre‐eclampsia, and 50 ...
Bismark Opoku Mensah, Ernestina Anim, Linda Ahenkorah Fondjo, Bernard Gyan, Peter Paul Mwinsanga Dapare   +4 more
wiley   +1 more source

The impact of low‐dose aspirin on hemoglobin levels in pregnancy: A secondary analysis of a randomized controlled trial for prevention of hypertensive disorders of pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives This study evaluates the association of low‐dose aspirin (LDA) with hemoglobin (Hb) levels during pregnancy and explores how changes in Hb levels relate to hypertensive disorders of pregnancy (HDP). Methods This secondary analysis of a randomized controlled trial comprised 249 pregnant women recruited from a regional hospital in ...
N. M. Ngcobo, V. Dorsamy, C. Bagwandeen, P. Z. Mkhize, J. Moodley   +4 more
wiley   +1 more source

Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials.

The Lancet Diabetes and Endocrinology, 2019
H. Heerspink, T. Greene, H. Tighiouart, R. Gansevoort, J. Coresh, Andrew L. Simon, T. Chan, F. Hou, J. Lewis, F. Locatelli, M. Praga, F. Schena, A. Levey, L. Inker   +13 more
semanticscholar   +1 more source