Results 321 to 330 of about 125,121 (369)

Carbonic Anhydrase 12 as a Novel Prognostic Biomarker and Therapeutic Target for High‐Risk Follicular Thyroid Carcinoma

Cancer Science, EarlyView.
In this study, we identified a novel biomarker, carbonic anhydrase 12 (CA12), to better distinguish high‐risk follicular thyroid carcinoma (FTC). High CA12 expression is associated with poor prognosis and CA12 promotes tumor cell growth and invasion. This study suggests that CA12 is not only an independent predictor of disease‐free survival but also a ...
Masashi Tanida, Tsuyoshi Takashima, Shinichiro Tahara, Masaharu Kohara, Haruka Kanai, Masami Suzuki, Motoyuki Suzuki, Mitsuyoshi Hirokawa, Ayana Suzuki, Shinya Sato, Daisuke Okuzaki, Satoshi Nojima, Takahiro Matsui, Hidenori Inohara, Eiichi Morii   +14 more
wiley   +1 more source

<i>PAX2</i>-Associated Kidney Dysplasia and Podocyte Injury: 2 Faces of a Monogenic Disorder. [PDF]

Kidney Int Rep
Kohl S, Liebau MC.
europepmc   +1 more source

Surgical Outcomes Following Neoadjuvant‐Targeted Therapy for Advanced Differentiated Thyroid Cancer—Real‐World Data

Clinical Endocrinology, EarlyView.
ABSTRACT Background Differentiated thyroid carcinoma (DTC) is typically managed surgically with favourable outcomes. However, surgery may have dire consequences when the tumour invades critical structures. Neoadjuvant therapy with tyrosine kinase inhibitors (TKIs) has emerged as a potential strategy to improve resectability and reduce morbidity in ...
Alexandra Dorman, Genady Shendler, Anton Warshavsky, Nidal Muhanna, Gilad Horowitz, Liyona Kampel Furman, Shahaf Shilo, Ben‐Zion Joshua, Eran Alon, Eric Remer, Galit Avior, Avi Khafif, Orit Gutfeld, Elena Izkhakov, Jobran Mansour, Inbar Finkel   +15 more
wiley   +1 more source

Diabetes management in maternally inherited diabetes and deafness (MIDD): A review and a proposed treatment algorithm

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry, David M. Thompson, Jean‐Pierre Chanoine   +2 more
wiley   +1 more source

Albuminuria is independently associated with preclinical left ventricular systolic dysfunction: The TESEO study. [PDF]

World J Diabetes
Barutta F, Andreis A, Bellettini M, Beccuti G, Ferro A, Bollati M, Bellini S, Gioiello G, Mengozzi G, De Ferrari GM, Alunni G, Broglio F, Gruden G.   +12 more
europepmc   +1 more source

Estimating the risk of cardiovascular outcomes and all‐cause mortality in individuals with type 2 diabetes: Validation of the UKPDS outcomes model using TECOS and EXSCEL data

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To evaluate United Kingdom Prospective Diabetes Study Outcomes Model version 2 (UKPDS‐OM2) cardiovascular risk estimates for people with type 2 diabetes using TECOS and EXSCEL data. Materials and methods We compared model‐simulated and TECOS and EXSCEL observed event rates for the composite outcome of cardiovascular death, myocardial ...
Ruth L. Coleman, Amanda I. Adler, Philip M. Clarke, Darren K. McGuire, Rury R. Holman   +4 more
wiley   +1 more source

Donor-derived PLA2R-positive membranous nephropathy after post-mortal kidney transplantation. [PDF]

Clin Kidney J
Baarz BR, Jochims J, Unterwalder N, Amann K, Eckardt KU, Choi M.   +5 more
europepmc   +1 more source

Continuous glucose monitoring and microvascular complications in diabetes: Bridging glycemic metrics with clinical outcomes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Continuous glucose monitoring (CGM) has emerged as a complementary and more dynamic method for evaluating glycemic control in people with diabetes. Relevant studies examining the association between CGM parameters, including time in range (TIR), glycemic variability (GV), and time in tight range (TITR), and diabetic nephropathy, retinopathy ...
Lilian Anagnostopoulou, Alexandros L. Liarakos, Ioannis Ntanasis‐Stathopoulos, Alexandros Briasoulis, Anastasios Tentolouris   +4 more
wiley   +1 more source

Effects of SGLT2 inhibitors across the spectrum of albuminuria in cardiovascular–kidney–metabolic conditions: A pooled analysis of randomised trials

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Background Albuminuria is associated with an increased risk of cardiovascular and kidney events. Sodium glucose co‐transporter 2 inhibitors (SGLT2i) reduce albuminuria and improve kidney outcomes in patients with albuminuric chronic kidney disease (CKD).
João Pedro Ferreira, Pedro Marques, Stefan D. Anker, Javed Butler, Gerasimos Filippatos, Abhinav Sharma, Francisco Vasques‐Nóvoa, Luís Mendonça, João Sérgio Neves, Milton Packer, Faiez Zannad   +10 more
wiley   +1 more source

Clinical Profile and Determinants of Chronic Kidney Disease Progression in Patients With Cardiorenal Anaemia Syndrome in Tanzania: A Descriptive Post Hoc Prospective Observational Study. [PDF]

Health Sci Rep
Edwin G, Alphonce B, Meremo A, Meda J.
europepmc   +1 more source