Results 31 to 40 of about 121,309 (370)
Prevalence of Hypertension and Albuminuria in Pediatric Type 2 Diabetes
JAMA Network Open, 2021 Key Points Question What is the prevalence of hypertension and albuminuria in children and adolescents with type 2 diabetes? Findings This systematic review and meta-analysis of 60 studies found that 25% of children and adolescents with type 2 diabetes ...
Milena Cioana +14 more
semanticscholar +1 more source
Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]
, 2019 Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica +7 more
core +1 more source
Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]
, 2014 Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G. +6 more
core +1 more source
Advances in Therapy, 2020 Introduction The Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guidelines recommend classifying patients by glomerular filtration rate (GFR) and albuminuria to predict chronic kidney disease (CKD) prognosis. The aim of this systematic review was
M. Murton +9 more
semanticscholar +1 more source
Albuminuria within the Normal Range Can Predict All-Cause Mortality and Cardiovascular Mortality
Kidney360, 2021 Key Points Despite interest in low-grade albuminuria and poor clinical outcomes, evidence from a large-scale population is lacking. In this large cohort study, low-grade albuminuria was associated with all-cause and cardiovascular mortality.
Minjung Kang +10 more
semanticscholar +1 more source
Baseline characteristics and enrichment results from the SONAR trial [PDF]
, 2018 Aim: The SONAR trial uses an enrichment design based on the individual response to the selective endothelin receptor antagonist atrasentan on efficacy (the degree of the individual response in the urinary albumin‐to‐creatinine ratio [UACR]) and safety/
Andress, Dennis L. +15 more
core +3 more sources
On the origin of albuminuria [PDF]
Kidney International, 2007 To the Editor: Russo et al.1 recently reported that the normal glomerulus filters nephrotic levels of albumin, followed by rapid endocytosis into proximal tubular cells (PTCs). Using 2-photon microscopy, they found more fluorescent albumin in the tubular lumen of puromycin aminonucleoside nephrotic rats than in healthy rats, but reduced albumin ...
openaire +3 more sources
American Journal of Kidney Diseases, 2019 The US Food and Drug Administration (FDA) and European Medicines Agency (EMA) are currently willing to consider a 30% to 40% glomerular filtration rate (GFR) decline as a surrogate end point for kidney failure for clinical trials of kidney disease ...
A. Levey +19 more
semanticscholar +1 more source
Journal of the American Society of Nephrology, 2020 BACKGROUND The association between early changes in albuminuria and kidney and cardiovascular events is primarily based on trials of renin-angiotensin system blockade.
M. Oshima +15 more
semanticscholar +1 more source