Results 31 to 40 of about 87,895 (325)
On the origin of albuminuria [PDF]
To the Editor: Russo et al.1 recently reported that the normal glomerulus filters nephrotic levels of albumin, followed by rapid endocytosis into proximal tubular cells (PTCs). Using 2-photon microscopy, they found more fluorescent albumin in the tubular lumen of puromycin aminonucleoside nephrotic rats than in healthy rats, but reduced albumin ...
openaire +3 more sources
Background There is a high hospitalization rate for diabetic patients. Since retinopathy and albuminuria are both important manifestations of microvascular disease in diabetes, our aim was to investigate the effect of retinopathy and albuminuria on long ...
Ya-Mei Hsieh+5 more
doaj +1 more source
Baseline characteristics and enrichment results from the SONAR trial [PDF]
Aim: The SONAR trial uses an enrichment design based on the individual response to the selective endothelin receptor antagonist atrasentan on efficacy (the degree of the individual response in the urinary albumin‐to‐creatinine ratio [UACR]) and safety/
Andress, Dennis L.+15 more
core +3 more sources
B lineage cells have been identified as therapeutic targets in autoimmune diseases. In the current review article, we provide an overview of novel strategies to target B lineage cells in autoimmune diseases, with a focus on inflammatory rheumatic diseases.
Ana Merino‐Vico+3 more
wiley +1 more source
Prevalence and Determinants of Diabetic Nephropathy in Korea: Korea National Health and Nutrition Examination Survey [PDF]
BackgroundDiabetic nephropathy is a leading cause of end stage renal disease and is associated with an increased risk of cardiovascular mortality. It manifests as albuminuria or impaired glomerular filtration rate (GFR), and the prevalence of diabetic ...
Jae Hee Ahn+14 more
doaj +1 more source
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou+13 more
wiley +1 more source
Albuminuria Screening in People With Type 2 Diabetes in a Managed Care Organization
Introduction: Albuminuria—an increased amount of urine albumin, in milligrams, adjusted for grams of urine creatinine—is an early marker of diabetic kidney disease.
Farrah Keong, MPH+5 more
doaj
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino+14 more
wiley +1 more source