Results 31 to 40 of about 96,519 (180)

Differential renal effects of candesartan at high-and ultra-high doses in diabetic mice: potential role of  ACE2/AT2R/Mas [PDF]

, 2016
High doses of Ang II receptor (AT1R) blockers (ARBs) are renoprotective in diabetes. Underlying mechanisms remain unclear. We evaluated whether high/ultra-high doses of candesartan (ARB) up-regulate angiotensin-converting enzyme 2 (ACE2)/Ang II type 2 ...
Antunes, Tayze, Briones, Ana M., Burns, Kevin, Callera, Glaucia, Correa, Jose, Gutsol, Alexey, He, Ying, Montezano, Augusto C., Moorman, Danielle, Nguyen Dinh Cat, Aurelie, Touyz, Rhian M.   +10 more
core   +1 more source

Determination of Albuminuria as a Component of Screening for Type 2 Diabetes Mellitus

Mìžnarodnij Endokrinologìčnij Žurnal, 2015
Objective of the Study. Determining the prevalence of albuminuria in patients with diagnosed diabetes mellitus type 2 (DM2). Materials and Methods of the Study.
L.O. Prystupiuk
doaj   +1 more source

Tissue lipidomic profiling supports a mechanistic role of the prostaglandin E2 pathway for albuminuria development in glomerular hyperfiltration

Frontiers in Network Physiology, 2023
Background: Glomerular hyperfiltration (GH) is an important mechanism in the development of albuminuria in hypertension. The Munich Wistar Frömter (MWF) rat is a non-diabetic model of chronic kidney disease (CKD) with GH due to inherited low nephron ...
Debora Kaiser-Graf, Angela Schulz, Eva Mangelsen, Michael Rothe, Juliane Bolbrinker, Reinhold Kreutz   +5 more
doaj   +1 more source

Prevalence of Albuminuria and Associated Factors among Gout Arthritis Patients in Cipto Mangunkusumo Hospital

Indonesian Journal of Rheumatology, 2018
Background Gout arthritis associates with many comorbodities such as hyperuricemia, hypertension, hyperglycemia, obesity, and dyslipidemia, which are also factors for the development of/or predisposition factors of chronic kidney diseases (CKD ...
Jeffrey Christian Mahardhika, R.M. Suryo Anggoro   +1 more
doaj   +1 more source

Increased prevalence of albuminuria in HIV-infected adults with diabetes.

PLoS ONE, 2011
ObjectiveHIV and type 2 diabetes are known risk factors for albuminuria, but no previous reports have characterized albuminuria in HIV-infected patients with diabetes.Research design and methodsWe performed a cross-sectional study including 73 HIV ...
Peter S Kim, Christian Woods, Lauren Dutcher, Patrick Georgoff, Alice Rosenberg, Jo Ann M Mican, Jeffrey B Kopp, Margo A Smith, Colleen Hadigan   +8 more
doaj   +1 more source

Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]

, 2015
OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst, Cavalot, Chun Shing Kwok, Evangelos Kontopantelis, Foo, Grant Heatlie, Hermann, Iain Buchan, Kontopantelis, Lin, Maciejewski, Mamas A. Mamas, Martin K. Rutter, Phyo K. Myint, Raman, Saadia Aslam, Skriver, Sperrin, Yoon Loke   +18 more
core   +1 more source

Urinary albumin creatinine ratio is associated with lipid profile

Scientific Reports
Moderately elevated albuminuria (30–300 mg/g) is a marker of renal dysfunction and a risk factor of cardiovascular disease. Additionally, several recent studies have reported a relationship between moderately elevated albuminuria and triglyceride (TG ...
Sang Won Hwang, Taesic Lee, Young Uh, Jun Young Lee   +3 more
doaj   +1 more source

Prevalence and Determinants of Diabetic Nephropathy in Korea: Korea National Health and Nutrition Examination Survey [PDF]

Diabetes & Metabolism Journal, 2014
BackgroundDiabetic nephropathy is a leading cause of end stage renal disease and is associated with an increased risk of cardiovascular mortality. It manifests as albuminuria or impaired glomerular filtration rate (GFR), and the prevalence of diabetic ...
Jae Hee Ahn, Ji Hee Yu, Seung-Hyun Ko, Hyuk-Sang Kwon, Dae Jung Kim, Jae Hyeon Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Soo Lim, Sung Hee Choi, Kyungdo Han, Bong-Yun Cha, Nan Hee Kim,   +14 more
doaj   +1 more source

Association of domain-specific physical activity with albuminuria among prediabetes and diabetes: a large cross-sectional study

Journal of Translational Medicine
Background Albuminuria, the presence of excess of protein in urine, is a well-known risk factor for early kidney damage among diabetic/prediabetic patients. There is a complex interaction between physical activity (PA) and albuminuria.
Bingquan Xiong, Yufan Wang, Juan He, Lisha Wang, Rui He, Min Zhu, Jiaxing Wang, Yingrui Li, Bin Liu, Kaihu Xiao, Qiang She   +10 more
doaj   +1 more source

Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]

, 2015
Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E, Divers, Jasmin, Freedman, Barry I, Hawfield, Amret T, Kaysen, George A, Kimmel, Paul L, Langefeld, Carl D, Pajewski, Nicholas M, Raj, Dominic S, Reboussin, David M, Ricardo, Ana C, Rocco, Michael V, Sedor, John R, Systolic Blood Pressure Intervention Trial (SPRINT), Wright, Jackson T   +14 more
core   +1 more source