Results 41 to 50 of about 85,863 (235)
Urinary peptide-based classifier CKD273: towards clinical application in chronic kidney disease [PDF]
, 2017 Capillary electrophoresis coupled with mass spectrometry (CE-MS) has been used as a platform for discovery and validation of urinary peptides associated with chronic kidney disease (CKD).
Mischak, Harald, Pontillo, Claudia
core +1 more source
Arthritis &Rheumatology, Accepted Article.Objective The presence of anti‐nuclear antibodies (ANAs) is characteristic for systemic lupus erythematosus (SLE). Antibody dynamics over time are thought to reflect the cellular source of ANAs and their therapeutic targetability. Anti‐dsDNA is the most prevalent and well‐studied of all ANAs, and fluctuations in anti‐dsDNA serum levels are associated ...
Hugo J. van Dooren +16 more
wiley +1 more source
Mucosal‐associated invariant T cells in rheumatic diseases.
Arthritis &Rheumatology, Accepted Article.Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor (TCR) and restriction by the MHC class I‐related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines. Upon activation, MAIT cells rapidly produce pro‐inflammatory cytokines,
Manon Lesturgie‐Talarek +7 more
wiley +1 more source
Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]
, 2015 OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst +18 more
core +1 more source
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Arthritis &Rheumatology, Accepted Article.Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen +2 more
wiley +1 more source
Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]
, 2015 Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E +14 more
core +1 more source
EXPERIMENTAL ALBUMINURIA IN THE RABBIT [PDF]
Archives of Pediatrics & Adolescent Medicine, 1921 It is a well recognized fact that the excretion of albumin in the urine occurs in circulatory disturbances of the kidneys. As the kidney is very sensitive to circulatory disorders, albuminuria may occur (except in nephritis) either because of local congestion of the veins and capillaries, or because of anemic infarct of the kidney. It may also occur in
Kumataro Gondo, Hideo Saito
openaire +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen +9 more
wiley +1 more source