Results 41 to 50 of about 123,506 (328)

Burden of Chronic Kidney Disease by KDIGO Categories of Glomerular Filtration Rate and Albuminuria: A Systematic Review

Advances in Therapy, 2020
Introduction The Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guidelines recommend classifying patients by glomerular filtration rate (GFR) and albuminuria to predict chronic kidney disease (CKD) prognosis. The aim of this systematic review was
M. Murton, D. Goff-Leggett, A. Bobrowska, Juan José Garcia Sanchez, G. James, E. Wittbrodt, S. Nolan, E. Sörstadius, R. Pecoits-Filho, K. Tuttle   +9 more
semanticscholar   +1 more source

Albuminuria within the Normal Range Can Predict All-Cause Mortality and Cardiovascular Mortality

Kidney360, 2021
Key Points Despite interest in low-grade albuminuria and poor clinical outcomes, evidence from a large-scale population is lacking. In this large cohort study, low-grade albuminuria was associated with all-cause and cardiovascular mortality.
Minjung Kang, S. Kwon, Jeonghwan Lee, Jung-Im Shin, Hyun Kwon, J. Park, E. Bae, Eun Young Kim, D. K. Kim, C. Lim, J. P. Lee   +10 more
semanticscholar   +1 more source

Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]

, 2014
Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G., Freel, E. Marie, Jardine, Alan G., Mark, Patrick, McQuarrie, Emily P., Taylor, Alison H., Traynor, Jamie P.   +6 more
core   +1 more source

Change in Albuminuria and GFR as End Points for Clinical Trials in Early Stages of CKD: A Scientific Workshop Sponsored by the National Kidney Foundation in Collaboration With the US Food and Drug Administration and European Medicines Agency.

American Journal of Kidney Diseases, 2019
The US Food and Drug Administration (FDA) and European Medicines Agency (EMA) are currently willing to consider a 30% to 40% glomerular filtration rate (GFR) decline as a surrogate end point for kidney failure for clinical trials of kidney disease ...
A. Levey, R. Gansevoort, J. Coresh, L. Inker, H. Heerspink, Morgan E. Grams, T. Greene, H. Tighiouart, K. Matsushita, S. Ballew, Y. Sang, E. Vonesh, Jian Ying, Tom Manley, D. de Zeeuw, K. Eckardt, A. Levin, V. Perkovic, Luxia Zhang, K. Willis   +19 more
semanticscholar   +1 more source

Early Change in Albuminuria with Canagliflozin Predicts Kidney and Cardiovascular Outcomes: A Post Hoc Analysis from the CREDENCE Trial.

Journal of the American Society of Nephrology, 2020
BACKGROUND The association between early changes in albuminuria and kidney and cardiovascular events is primarily based on trials of renin-angiotensin system blockade.
M. Oshima, B. Neuen, Jingwei Li, V. Perkovic, D. Charytan, D. de Zeeuw, Robert Edwards, T. Greene, A. Levin, K. Mahaffey, L. De Nicola, C. Pollock, N. Rosenthal, D. Wheeler, M. Jardine, H. Heerspink   +15 more
semanticscholar   +1 more source

Anatomical and functional remodeling of left ventricle in patients with primary aldosteronism and concomitant albuminuria

Therapeutic Advances in Chronic Disease, 2023
Background: Primary aldosteronism (PA) is the leading cause of secondary hypertension globally and is associated with adverse cardiovascular outcomes. However, the cardiac impact of concomitant albuminuria remains unknown.
Ting-Wei Kao, Xue-Ming Wu, Che-Wei Liao, Cheng-Hsuan Tsai, Zheng-Wei Chen, Yi-Yao Chang, Bo-Ching Lee, Yu-Wei Chiu, Tai-Shuan Lai, Vin-Cent Wu, Yen-Hung Lin, Chi-Sheng Hung,   +12 more
doaj   +1 more source

Urinary proteomics using capillary electrophoresis coupled to mass spectrometry for diagnosis and prognosis in kidney diseases [PDF]

, 2016
Purpose of review: Urine is the most useful of body fluids for biomarker research. Therefore, we have focused on urinary proteomics, using capillary electrophoresis coupled to mass spectrometry, to investigate kidney diseases in recent years.
Magalhães, Pedro, Mischak, Harald, Zürbig, Petra   +2 more
core   +1 more source

Inpatient screening for albuminuria and retinopathy to predict long-term mortality in type 2 diabetic patients: a retrospective cohort study

Diabetology & Metabolic Syndrome, 2017
Background There is a high hospitalization rate for diabetic patients. Since retinopathy and albuminuria are both important manifestations of microvascular disease in diabetes, our aim was to investigate the effect of retinopathy and albuminuria on long ...
Ya-Mei Hsieh, Wen-Jane Lee, Wayne H.-H. Sheu, Yu-Hsuan Li, Shih-Yi Lin, I.-Te Lee   +5 more
doaj   +1 more source

Baseline characteristics and enrichment results from the SONAR trial [PDF]

, 2018
Aim: The SONAR trial uses an enrichment design based on the individual response to the selective endothelin receptor antagonist atrasentan on efficacy (the degree of the individual response in the urinary albumin‐to‐creatinine ratio [UACR]) and safety/
Andress, Dennis L., Bakris, George, Brennan, John J., Correa-Rotter, Ricardo, de Zeeuw, Dick, Heerspink, Hiddo J.L., Hou, Fan Fan, Kitzman, Dalane W., Kohan, Donald, Makino, Hirofumi, McMurray, John, Parving, Hans-Henrik, Perkovic, Vlado, Tobe, Sheldon, Wigderson, Melissa, Yi, Tingting   +15 more
core   +3 more sources

The bidirectional association between depressive symptoms, assessed by the HADS, and albuminuria–A longitudinal population-based cohort study with repeated measures from the HUNT2 and HUNT3 Study

PLoS ONE, 2022
Background Both albuminuria and depression are associated with cardiovascular disease, reflecting low-grade systemic inflammation and endothelial dysfunction.
Lise Tuset Gustad, Anna Marie Holand, Torfinn Hynnekleiv, Ottar Bjerkeset, Michael Berk, Solfrid Romundstad   +5 more
doaj   +2 more sources