Results 41 to 50 of about 96,519 (180)

Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial [PDF]

, 2016
Introduction: Diabetes mellitus affects 9% of the European population and accounts for 15% of healthcare expenditure, in particular, due to excess costs related to complications.
Beige, Joachim, Currie, Gemma, Delles, Christian, Lindhardt, Morten, Mischak, Harald, Navis, Gerjan, Noutsou, Marina, Ortiz, Alberto, Persson, Frederik, Pontillo, Claudia, Rossing, Peter, Ruggenenti, Piero Luigi, Rychlik, Ivan, Spasovski, Goce, von der Leyen, Heiko   +14 more
core   +4 more sources

Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: United Kingdom Heart and Renal Protection (HARP)- III—rationale, trial design and baseline data [PDF]

, 2016
BACKGROUND: Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and animal experiments suggest that neprilysin inhibition (which augments the ...
Baigent, C., Baxter, A., Bethel, A., Bowman, L., Brunskill, N., Cockwell, P., Dayanandan, R., Emberson, J., Haynes, R., Herrington, W.G., Hill, M., Judge, P.K., Kalra, P.A., Knott, C., Landray, M.J., McMurray, John J., Murphy, K., Roderick, P., Staplin, N., Storey, B.C., Taal, M., Tomson, C., Wheatley, K., Wheeler, D.C.   +23 more
core   +1 more source

Albuminuria during treatment with angiotensin type II receptor blocker is a predictor for GFR decline among non-diabetic hypertensive CKD patients. [PDF]

PLoS ONE, 2018
BACKGROUND:Albuminuria is a predictor of disease progression in patients with chronic kidney disease (CKD). However, the ability of proteinuria parameters measured at various time periods to predict renal outcomes is unclear.
Mi-Yeon Yu, Dong Ki Kim, Jung Hwan Park, Sung Joon Shin, Sang Ho Lee, Bum Soon Choi, Chun Soo Lim, Ho Jun Chin   +7 more
doaj   +1 more source

Urinary peptide-based classifier CKD273: towards clinical application in chronic kidney disease [PDF]

, 2017
Capillary electrophoresis coupled with mass spectrometry (CE-MS) has been used as a platform for discovery and validation of urinary peptides associated with chronic kidney disease (CKD).
Mischak, Harald, Pontillo, Claudia
core   +1 more source

TLR-mediated albuminuria needs TNFα-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice

Disease Models & Mechanisms, 2016
Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS).
Nidhi Jain, Bhavya Khullar, Neelam Oswal, Balaji Banoth, Prashant Joshi, Balachandran Ravindran, Subrat Panda, Soumen Basak, Anna George, Satyajit Rath, Vineeta Bal, Shailaja Sopory   +11 more
doaj   +1 more source

FREQUENCY OF MICROALBUMINURIA IN THE MIDDLE AGE AND OLDER POPULATION OF PESHAWAR CITY

Pakistan Armed Forces Medical Journal, 2018
Objectives: To determine the frequency of micro albuminuria in the middle age and older population of both genders in Peshawar city of Pakistan. Study Design: Random control study. Place and Duration of Study: This study was carried out from Jan
Mohammad Yousaf, Muzammil Arshad, Kehkasha Sabir, Ibrahim ., Razaullah .   +4 more
doaj  

The association between weekend warrior physical activity pattern and albuminuria in hypertensive patients

BMC Public Health
Background Albuminuria, a critical and sensitive indicator of vascular injury, has been linked to early kidney damage in patients with hypertension. High-quality physical activity (PA) may reduce urinary albumin excretion.
Bingquan Xiong, Wenlong Yu, Xinyi Guan, Zhuo Tian, Min Zhu, Huiping Yang, Jiaxin Wang, Yingrui Li, Bin Liu, Yufan Wang, Qiang She   +10 more
doaj   +1 more source

Albuminuria status and patterns of dyslipidemia among type 2 diabetes black patients managed at a tertiary health-care hospital: A Post hoc analysis

Saudi Journal of Kidney Diseases and Transplantation, 2018
Cardiovascular disease (CVD) risk in type 2 diabetes mellitus (T2DM) increases with the development of albuminuria and is related in part to dyslipidemia. The present analysis assessed lipid profile and patterns of dyslipidemia in T2DM patients according
Francois M Kajingulu, Francois B Lepira, Fiston I Mbutiwi, Jean-Robert Makulo, Ernest K Sumaili, Justine B Bukabau, Vieux M Mokoli, Augustin L Longo, Nazaire M Nseka   +8 more
doaj   +1 more source

Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease. [PDF]

, 2014
The renin-angiotensin system (RAS), bone morphogenetic protein (BMP), and WNT pathways are involved in pathogenesis of diabetic kidney disease (DKD).
Afkarian, Maryam, de Boer, Ian H, Greenbaum, Carla, Himmelfarb, Jonathan, Hirsch, Irl B, Tuttle, Katherine R   +5 more
core   +1 more source

Prevalencia de Micro albuminuria en pacientes hipertensos no diabéticos

Revista de la Facultad de Medicina, 2017
Introducción: Se ha demostrado que la presencia de micro albuminuria puede reflejar el desarrollo de enfermedad cardiovascular en pacientes con diabetes mellitus, este fenómeno también se ha observado en pacientes no diabéticos.
Sofia Roldán, Clara Chang
doaj   +1 more source