Results 41 to 50 of about 87,895 (325)
Inference and Prediction Using Functional Principal Components Analysis: Application to Diabetic Kidney Disease Progression in the Chronic Renal Insufficiency Cohort (CRIC) Study [PDF]
arXiv, 2022 Repeated longitudinal measurements are commonly used to model long-term disease progression, and timing and number of assessments per patient may vary, leading to irregularly spaced and sparse data. Longitudinal trajectories may exhibit curvilinear patterns, in which mixed linear regression methods may fail to capture true trends in the data.
arxiv
Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study. [PDF]
, 2018 BACKGROUND:Patients with chronic kidney disease (CKD) are at increased risk for heart failure (HF). We aimed to investigate differences in proteins associated with HF hospitalizations among patients with and without CKD in the Heart and Soul Study ...
Dubin, Ruth F +5 more
core +2 more sources
Human Mutation, Volume 43, Issue 12, Page 1866-1871, December 2022., 2022 Abstract Galloway–Mowat syndrome (GAMOS) is a very rare condition characterized by early‐onset nephrotic syndrome and microcephaly with variable neurologic features. While considerable genetic heterogeneity of GAMOS has been identified, the majority of cases are caused by pathogenic variants in genes encoding the four components of the Kinase ...
Ernestine Treimer +8 more
wiley +1 more source
Second-order group knockoffs with applications to GWAS [PDF]
arXiv, 2023 Conditional testing via the knockoff framework allows one to identify -- among large number of possible explanatory variables -- those that carry unique information about an outcome of interest, and also provides a false discovery rate guarantee on the selection.
arxiv
Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
, 2018 Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A
Human Mutation, Volume 43, Issue 12, Page 2265-2278, December 2022., 2022 Abstract A rare and fatal disease resembling mucopolysaccharidosis in infants, is caused by impaired intracellular endocytic trafficking due to deficiency of core components of the intracellular membrane‐tethering protein complexes, HOPS, and CORVET. Whole exome sequencing identified a novel VPS33A mutation in a patient suffering from a variant form of
Elena V. Pavlova +11 more
wiley +1 more source
Clinical and Experimental Hypertension, 2020 Aims Circulating miR-29b and inflammatory process play a vital role in hypertension and hypertensive nephropathy. The aim of the present study was to investigate the association of circulating miR-29b and inflammatory markers with albuminuria and assess ...
Cheng Huang, Yu-Qing Huang
doaj +1 more source
Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis [PDF]
, 2016 Background: Hypertension and proteinuria are critically involved in the progression of chronic kidney disease. Despite treatment with renin angiotensin system inhibition, kidney function declines in many patients.
Boesby, Lene +16 more
core +2 more sources
Pediatrics and Neonatology, 2016 We do not yet fully grasp the significance of childhood albuminuria. Based on mass urinary screening (MUS) using albumin-specific dipsticks in school children, we studied the independent association of estimated glomerular filtration rate (eGFR) and ...
Ching-Yuang Lin, Shiuh-Ming Huang
doaj +1 more source