Background Oral albuterol has worse efficacy and side effects compared with inhaled albuterol, and thus its use has been discouraged for decades. Drug inclusion or exclusion on formularies have been associated with reductions in low-value care.
Anna Volerman +4 more
doaj +2 more sources
Efficacy and safety of as-needed albuterol–budesonide versus albuterol in patients with asthma aged 12 to [PDF]
Introduction Asthma among adolescents (aged 12–<18 years) is a common condition with high disease burden. Many are undertreated, at risk of adverse outcomes and exhibit poor adherence to maintenance medication.
Raulin Surujbally +7 more
doaj +2 more sources
Limiting Albuterol Use by EMS at the Start of the COVID-19 Pandemic: A Retrospective Analysis of Rapid Deimplementation [PDF]
Introduction: Deimplementation is the process through which an existing practice, procedure, or protocol is discontinued. Past deimplementation efforts in emergency medical services (EMS), such as reduction of liberal oxygen administration, backboard use,
Renoj Varughese +7 more
doaj +2 more sources
Nebulized-Swallowed Albuterol for the Treatment of Food Impaction in Pediatric Patients with Eosinophilic Esophagitis: A Novel Nonendoscopic Approach [PDF]
Food impaction (FI) is a manifestation of eosinophilic esophagitis (EoE) and requires endoscopic removal. We report the response to nebulized albuterol in 5 children with EoE and FI.
Thirumazhisai S. Gunasekaran, MD +3 more
doaj +2 more sources
Assessing the cardiovascular and potassium lowering effects of levalbuterol compared to albuterol: a randomized control trial [PDF]
BackgroundBeta-agonists like Levalbuterol and Albuterol are used in the treatment of Hyperkalemia. However, few studies in the medical literature have directly compared the cardiac effects and potassium-lowering efficacy of levalbuterol and albuterol ...
Baraa Shebli +5 more
doaj +2 more sources
A 10-year interval of cardiovascular effects of albuterol in asthma management: Graphical review [PDF]
Asthma is a widespread chronic respiratory disease that requires effective management to reduce exacerbations and improve patient outcomes. Albuterol (salbutamol), a short-acting beta-2-agonist (SABA), remains a mainstay treatment for acute symptom ...
Ghulam H. Abbas +6 more
doaj +2 more sources
Long-acting β2 agonist (LABA) with a long-acting muscarinic receptor antagonist (LAMA) promotes human airway smooth muscle (HASM) relaxation and circumvents β2 adrenergic receptor tachyphylaxis [PDF]
To fill the gap in the knowledge between clinical studies and pre-clinical mechanistic studies using combined LABA/LAMA therapy, we hypothesized that the combination is more effective in attenuating excitation-contraction (E-C) coupling compared to ...
Joseph Jude +5 more
doaj +2 more sources
Dexmedetomidine as an adjunctive treatment for acute asthma [PDF]
Objective This study aimed to compare the efficacy of using dexmedetomidine with salbutamol and salbutamol nebulization alone in patients with acute exacerbation of asthma presenting to the emergency department.
Hassan Motamed +3 more
doaj +1 more source
Albuterol, Acidosis, and Aneurysms [PDF]
A patient with a complicated medical history on admission for dyspnea was administered nebulizer therapy but after 72 hours developed asymptomatic acute kidney injury and anion-gap metabolic acidosis.
Lucy, Ma +2 more
openaire +2 more sources
β2-Agonists inhibit TNF-α-induced ICAM-1 expression in human airway parasympathetic neurons. [PDF]
Major basic protein released from eosinophils to airway parasympathetic nerves blocks inhibitory M(2) muscarinic receptors on the parasympathetic nerves, increasing acetylcholine release and potentiating reflex bronchoconstriction.
Zhenying Nie +2 more
doaj +1 more source

