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Influence of ADRB2 variants on bronchodilator response and asthma control in a mixed population [PDF]

Jornal Brasileiro de Pneumologia
Objective: Given that b2 agonists constitute the primary treatment for asthma and that treatment response varies as a result of polymorphisms in the ADRB2 gene, we sought to investigate the associations between ADRB2 gene variants and bronchodilator ...
Pedro Augusto Silva dos Santos Rodrigues, Álvaro Augusto Souza da Cruz Filho, Helena Mariana Pitangueira Teixeira, Luciano Gama da Silva Gomes, Hatilla dos Santos Silva, Juliana Lopes Rodrigues, Almirane Lima de Oliveira, Cinthia Vila Nova Santana, Gabriela Pimentel Pinheiro das Chagas, Camila Alexandrina Viana de Figueiredo, Ryan dos Santos Costa   +10 more
doaj   +1 more source

A Delphi Consensus Document on the Use of Single-Inhaler Fixed-Dose Triple Therapies in COPD Patients

International Journal of COPD, 2020
José Luis López-Campos,1,2 Bernardino Alcázar Navarrete,3 Juan Antonio Riesco Miranda,2,4 Borja G Cosío,2,5 Juan P de-Torres,6 Bartolomé Celli,7 Carlos A Jiménez-Ruiz,8 Ciro Casanova Macario9 1Unidad Mé ...
López-Campos JL, Alcázar Navarrete B, Riesco Miranda JA, Cosío BG, de-Torres JP, Celli B, Jiménez-Ruiz CA, Casanova Macario C   +7 more
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Inhaler Devices for Delivery of LABA/LAMA Fixed-Dose Combinations in Patients with COPD

Pulmonary Therapy, 2019
Inhaled fixed-dose combinations (FDCs) of a long-acting β-agonist (LABA) and a long-acting muscarinic antagonist (LAMA) have become the cornerstone for the maintenance treatment of symptomatic COPD patients.
Anthony D’Urzo, Kenneth R. Chapman, James F. Donohue, Peter Kardos, M. Reza Maleki-Yazdi, David Price   +5 more
doaj   +1 more source

Current and potential improvements in the treatment of asthma from increased understanding of airway pathophysiology

Allergology International, 2002
The mainstay of chronic asthma management consists of using pharmacological agents that induce bronchodilatation, such as short-acting β-adrenergic receptor agonists (bronchodilators or relievers), and that control the chronic inflammatory process, such ...
Kian Fan Chung
doaj   +1 more source

Evaluating bronchodilator response in pediatric patients with post-infectious bronchiolitis obliterans: use of different criteria for identifying airway reversibility

Jornal Brasileiro de Pneumologia
Objective: Post-infectious bronchiolitis obliterans (PIBO) is a clinical entity that has been classified as constrictive, fixed obstruction of the lumen by fibrotic tissue.
Rita Mattiello, Paula Cristina Vidal, Edgar Enrique Sarria, Paulo Márcio Pitrez, Renato Tetelbom Stein, Helena Teresinha Mocelin, Gilberto Bueno Fischer, Marcus Herbert Jones, Leonardo Araújo Pinto   +8 more
doaj   +1 more source

Exploring the possibility of a predictable precision therapy of COPD with inclusion of glycopyrronium responsiveness: A real-world experience

Lung India
Background: The advent of glycopyrronium responsiveness has opened the prospect of selective responsiveness-based prescription of bronchodilators-β2-agonists or anti-muscarinic agents (AMA) for COPD.
Parthasarathi Bhattacharyya, Shuvam Ghosh, Srijita Sen, Debkanya Dey, Sayoni Sengupta, Saayon Bej, Avishek Kar, Dipanjan Saha   +7 more
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Indacaterol/glycopyrronium versus salmeterol/fluticasone in Asian patients with COPD at a high risk of exacerbations: results from the FLAME study

International Journal of COPD, 2017
Jadwiga A Wedzicha,1 Nanshan Zhong,2 Masakazu Ichinose,3 Michael Humphries,4 Robert Fogel,5 Chau Thach,5 Francesco Patalano,6 Donald Banerji5 1National Heart and Lung Institute, Imperial College London, London, UK; 2State Key Laboratory of Respiratory ...
Wedzicha JA, Zhong N, Ichinose M, Humphries M, Fogel R, Thach C, Patalano F, Banerji D   +7 more
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Randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD

International Journal of COPD, 2018
Yasushi Fukushima,1 Yuji Nakatani,2 Yumiko Ide,3 Hisakuni Sekino,4 Earl St Rose,5 Shahid Siddiqui,6 Andrea Maes,5 Colin Reisner5,6 1Department of Internal Medicine, Fukuwa Clinic, Tokyo, Japan; 2Department of Internal Medicine, Nakatani Hospital, Hyogo,
Fukushima Y, Nakatani Y, Ide Y, Sekino H, St Rose E, Siddiqui S, Maes A, Reisner C   +7 more
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Efficacy of tiotropium and olodaterol combination therapy on dynamic lung hyperinflation evaluated by hyperventilation in COPD: an open-label, comparative before and after treatment study

International Journal of COPD, 2019
Shohei Kawachi,1 Keisaku Fujimoto21Department of Biomedical Laboratory Science, Graduate School of Medicine, Shinshu University, Nagano 390-8621, Japan; 2Department of Clinical Laboratory Sciences, Shinshu University School of Health Sciences, Matsumoto ...
Kawachi S, Fujimoto K
doaj  

Early efficacy of budesonide/formoterol in patients with moderate-to-very-severe COPD

International Journal of COPD, 2016
Peter M Calverley,1 Göran Eriksson,2 Christine R Jenkins,3 Antonio R Anzueto,4 Barry J Make,5 Anders Persson,6 Malin Fagerås,6 Dirkje S Postma7 1Pulmonary and Rehabilitation Research Group, University Hospital Aintree, Liverpool, UK ...
Calverley PM, Eriksson G, Jenkins CR, Anzueto AR, Make BJ, Persson A, Fagerås M, Postma DS   +7 more
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