Results 41 to 50 of about 13,974 (221)
International Journal of COPD, 2023 Manuel Enrique Machado-Duque,1,2 Andrés Gaviria-Mendoza,1,2 Luis Fernando Valladales-Restrepo,1,2 Andrés González-Rangel,3 Maria Eugenia Laucho-Contreras,3,4 Jorge Enrique Machado-Alba1 1Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia,
Machado-Duque ME +5 more
doaj
Allergy, EarlyView.This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake +8 more
wiley +1 more source
Allergy, EarlyView.The SENDO cohort study (2015–2024) prospectively analyzed the impact of ultra‐processed food (UPF) consumption on asthma and atopy in 1,546 Spanish children. Higher UPF intake (NOVA 4 classification) was significantly associated with an increased risk of asthma but not atopy, atopic dermatitis, neumoallergen sensitation, food allergy over five years ...
O. Galindo +6 more
wiley +1 more source
New bronchodilators and combinations in COPD treatment [PDF]
, 2016 Bronchodilator drugs are widely used therapeutic agents for treatment of asthma and chronic obstructive pulmonary disease (COPD). In order to mantain bronchodilation, both sympathetic system (particularly beta-2 receptors) activation and parasympathetic ...
Gunay, Sibel +5 more
core +1 more source
Allergy, EarlyView.Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton +19 more
wiley +1 more source
Pathophysiology, clinical manifestation, and treatment of tuberculosis-associated chronic obstructive pulmonary disease: a narrative review [PDF]
The Ewha Medical JournalChronic obstructive pulmonary disease (COPD) is a leading cause of respiratory morbidity and mortality, most often linked to smoking. However, growing evidence indicates that previous tuberculosis (TB) infection is also a critical risk factor for COPD ...
Joon Young Choi
doaj +1 more source
BRONCHIAL RESPONSE TIME TO A BRONCHODILATING AGENT-ORCIPRENALINE
The Keio Journal of Medicine, 1973 The specific airway conductance (Gaw/Vtg) of 4 normal subjects and 5 subjects with respiratory diseases was measured before and after inhalation of orciprenaline. There was an almost maximum increase in Gaw/Vtg within 3 to 4 minutes in both groups of subjects after inhalation of orciprenaline.
KAGAWA, JUN +2 more
openaire +3 more sources
Allergy, EarlyView.ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin +4 more
wiley +1 more source
Screening of certain Ayurvedic plants extracts against E. turcicum [PDF]
, 2011 The use of chemicals against pathogens is environmentally dangerous, so use of natural inhibitors for disease management is needed. In this work we screen botanical extracts from ayurvedic plants for their antifungal properties against economically ...
R. Prasad +2 more
core +1 more source
Novel small airway bronchodilator responses to rosiglitazone in mouse lung slices [PDF]
, 2014 Fulltext embargoed for: 12 months post date of publicationThere is a need to identify novel agents that elicit small airway relaxation when β2-adrenoceptor agonists become ineffective in difficult-to-treat asthma.
Donovan, C +5 more
core +1 more source