Results 51 to 60 of about 417 (140)

[Tiotropium, a long-acting bronchodilating agent for the treatment of COPD]. [PDF]

Nederlands tijdschrift voor geneeskunde, 2006
The goals of COPD management according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline are: prevention of disease progression, relief of symptoms, improvement of exercise tolerance and the quality of life, prevention and treatment of exacerbations and complications, and reduction of mortality and adverse effects.
Schuurbiers, O.C.J., Schermer, T.R.J., Dekhuijzen, P.N.R., Weel, C. van   +3 more
openaire   +2 more sources

New β-diketone and 3,5-dimethyl isoxazole derivatives of theophylline as potential bronchodilator agents

, 1998
Ten new compounds having 7-[(2,4-pentanedione-3-yl)alkyl]- and 7-[(3,5- dimethylisoxazole-4-yl)alkyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione structures were synthesized and their bronchodilator activities investigated using the method based on ...
Batu, Özlem Sarniç, Akgün, Hülya, EROL, KEVSER, Balkan, Ayla   +3 more
core  

Occupational exposure to dusts, gases and fumes and incidence of chronic obstructive pulmonary disease in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults

, 2012
RATIONALE: There is limited evidence from population-based studies demonstrating incidence of spirometric-defined chronic obstructive pulmonary disease (COPD) in association with occupational exposures.
Probst-Hensch, N., Dep IRAS, Turk, A., Curjuric, I., Mehta, A.J., Curjuric, Ivan, Turk, Alexander, Bettschart, R., Russi, Erich W, Bridevaux, P.O., Rochat, Thierry, Keidel, Dirk, Thierry Rochat, Probst-Hensch, Nicole, Schwartz, Joel, Schikowski, Tamara, Russi, E. W., Bircher, Andreas, Russi, E.W., Ivan Curjuric, Miedinger, D., Amar J. Mehta, Curjuric, I, Robert Bettschart, Joel Schwartz, Kromhout, H., Kromhout, Hans, Pierre-Olivier Bridevaux, Erich W. Russi, Nino Künzli, David Miedinger, Rothe, Thomas, Rothe, T., Andreas Bircher, Roel Vermeulen, Dirk Keidel, Thomas Rothe, Mehta, Amar J, Schwartz, J., Mehta, A. J., Bridevaux, P. O., Vermeulen, Roel, Risk Assessment of Toxic and Immunomodulatory Agents, Rochat, T., Tamara Schikowski, Christian Schindler, Vermeulen, R., Miedinger, David, Hans Kromhout, Bircher, A., Schikowski, T., Bettschart, Robert, Künzli, Nino, Künzli, N., Alexander Turk, Keidel, D., Bridevaux, Pierre-Olivier, Nicole Probst-Hensch, Schindler, Christian, Schindler, C.   +59 more
core   +1 more source

Pharmacology and therapeutics of bronchodilators [PDF]

, 2012
Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of the current management of chronic obstructive pulmonary disease (COPD) and are critical in the symptomatic management of asthma, although controversies around ...
Matera MG, Cazzola M, Calzetta, L, Clive P. Page, Calzetta L, Calzetta, Luigino, Cazzola, M, Luigino Calzetta, Page CP, Page, Clive P., Page, CP, CAZZOLA, MARIO, Mario Cazzola, Matera, M. Gabriella, Matera, MG, MATERA, Maria Gabriella, M. Gabriella Matera   +16 more
core   +1 more source

Bronchodilator response is linked with uncontrolled moderate‐to‐severe childhood asthma and elevated IL‐4 and IL‐13

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
High BDR (≥10% FEV1) predicts 3‐fold higher odds of poor asthma control in children with moderate‐to‐severe asthma. High BDR links to elevated T2 cytokines (IL‐4, IL‐13) and non‐T2 mediators (IL‐1β, IL‐6, IL‐7, IL‐8, TNF‐α), as well as MMP‐1. BDR offers non‐invasive phenotyping potential to advance personalized asthma management.
Nariman K. A. Metwally, Simone Hashimoto, Susanne J. H. Vijverberg, Anne H. Neerincx, Barbara S. Dierdorp, Tamara Dekker, Eric G. Haarman, Jan Willem Duitman, Mario Gorenjak, Antoaneta A. Toncheva, Susanne Harner, Susanne Brandstetter, Christine Wolff, Paula Corcuera‐Elosegui, Leyre López‐Fernández, Olaia Sardón‐Prado, Maria Pino‐Yanes, Uroš Potočnik, Michael Kabesch, Aletta D. Kraneveld, René Lutter, Suzanne W. J. Terheggen‐Lagro, Mahmoud I. Abdel‐Aziz, Anke H. Maitland‐van der Zee, on behalf of the SysPharmPediA Consortium   +24 more
wiley   +1 more source

New ß-diketone and 3,5-dimethyl isoxazole derivatives of theophylline as potential bronchodilator agents

, 1998
PubMed: 9689423Ten new compounds having 7-[(2,4-pentanedione-3-yl)alkyl]- and 7-[(3,5- dimethylisoxazole-4-yl)alkyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione structures were synthesized and their bronchodilator activities investigated using the ...
Balkan, A., Akgün, H., Erol, Kevser, Batu, Ö. S.   +3 more
core  

Cost comparison of two aerosol bronchodilator delivery methods in patients with acute asthma in the emergency department : intermittent nebulization versus metered-dose inhaler with valved spacer [PDF]

, 2002
Objetivo: A administração de broncodilatadores através de dispositivo com aerossol dosimetrado (spray) ou através de nebulizador é equivalente em eficácia no tratamento da asma aguda. Alguns estudos sugerem que o spray tem um custo menor.
Hoffmann, Cristine Feliciati, Fernandes, Andreia Kist, Mallmann, Felipe, Krost, Daniel Papich, Franciscatto, Eduardo, Innocenti, Cassiano, Dalcin, Paulo de Tarso Roth, Kang, Suzie Hyeona, Piovesan, Deise Marcela   +8 more
core  

Novel Bronchodilators:  Synthesis, Transamination Reactions, and Pharmacology of a Series of Pyrazino[2,3-c][1,2,6]thiadiazine 2,2-Dioxides

, 2016
The synthesis, pharmacological evaluation, and structure−activity relationships of a new class of bronchodilator agents, derivatives of pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxides are described.
Concepción García (363008), Juan A. Páez (3011922), Ibon Alkorta (537241), Pilar Goya (397723), Nuria Campillo (3011925)   +4 more
core   +1 more source

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda, Renu Khasa, Srinivasan Chinnapaiyan, Saurabh Aggarwal, Irfan Rahman, Hoshang Unwalla   +5 more
wiley   +1 more source

Novel bronchodilators: Synthesis, transamination reactions, and pharmacology of a series of pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxides

, 2000
The synthesis, pharmacological evaluation, and structure-activity relationships of a new class of bronchodilator agents, derivatives of pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxides are described.
Alkorta, Ibon, Goya, Pilar, Campillo, Nuria E., García-Gómez, Concepción, Páez, Juan A.   +4 more
core   +1 more source