COPD and glycopyrronium responsiveness assessment: An appraisal
Clinical Trial Registration: ECR/159/Inst/WB/2013/RR-20 Background: Glycopyrronium bromide (a long-acting antimuscarinic agent: LAMA) appears pharmacokinetically suitable for testing bronchodilator responsiveness as salbutamol (short-acting β2-agonist ...
Parthasarathi Bhattacharyya +5 more
doaj +1 more source
asthma and anti-asthmatic agents [PDF]
asthma is chronic inflammation of airway which causes shortness of breath, repeated coughing and wheezing. The treatment is bronchodilator, mast cell stabilizer, corticosteroid, anti IgE.gyógyszerészangolegységes ...
sherkat, fatemeh
core
Pharmacologic Therapies for Preventing Chronic Obstructive Pulmonary Disease Exacerbations: A Comprehensive Review [PDF]
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by acute exacerbations that accelerate disease progression, increase hospitalizations, and elevate mortality.
Hyun Woo Lee
doaj +1 more source
Improved ventricular function during inhalation of PGI(2) aerosol partly relies on enhanced myocardial contractility [PDF]
Inhaled prostacyclin (PGI(2)) aerosol induces selective pulmonary vasodilation. Further, it improves right ventricular ( RV) function, which may largely rely on pulmonary vasodilation, but also on enhanced myocardial contractility.
Thein, E. +12 more
core +1 more source
Therapeutic‐dose verapamil‐induced cardiogenic shock in an older patient: a case report
Abstract Background Calcium channel blocker (CCB) toxicity most commonly follows deliberate overdose. However, severe toxicity at therapeutic doses may occur in susceptible individuals. Severe CCB toxicity often presents with clinical features of bradycardia, hypotension, hyperglycaemia, and lactic acidosis.
Christopher Thuring +3 more
wiley +1 more source
Improved Metered Dose Inhaler Technique When a Coordination Cap Is Used [PDF]
Background: Patients often experience problems using metered dose inhalers (MDIs), particularly poor coordination between inhalation start and dose actuation (TsIn: time difference between the start of an inhalation and the actuation of a dose), and fast
Stephenson, John +9 more
core +1 more source
Short-acting β2-agonist prescriptions in patients with asthma: findings from the South Korean cohort of SABINA III [PDF]
Background/Aims Despite short-acting β2-agonist (SABA) overuse being associated with poor asthma outcomes, data on SABA use in South Korea is scarce.
Kwang-Ha Yoo +6 more
doaj +1 more source
Clinical Outcomes and Acute Exacerbation Incidence in Combined Pulmonary Fibrosis and Emphysema
This multicentre prospective study of 1016 patients demonstrated that CPFE, defined as ≥ 5% emphysema on visual CT assessment, identified a high‐risk phenotype with significantly worse 5‐year survival compared to non‐CPFE IIP patients (51.4% vs. 63.1%) and COPD patients (51.4% vs. 84.0%) and higher acute exacerbation incidence, validating international
Kazuya Tsubouchi +23 more
wiley +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
The role of the adrenal glands and of α- and β-adrenergic receptors in bronchodilatation of guinea-pig lungs in vivo [PDF]
Adrenaline, aminophylline, isoprenaline, noradrenaline, papaverine and phenylephrine exerted non-specific bronchodilator effects in guinea-pig lungs in vivo.
G W LYNN JAMES
core +1 more source

