How Glucocorticoids Affect the Neutrophil Life [PDF]
International Journal of Molecular Sciences, 2018 Glucocorticoids are hormones that regulate several functions in living organisms and synthetic glucocorticoids are the most powerful anti-inflammatory pharmacological tool that is currently available.
Simona Ronchetti +2 more
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New dimension of glucocorticoids in cancer treatment
Steroids, 2016 [[abstract]]Glucocorticoids have been used in clinical oncology for over half of the century. The clinical applications of glucocorticoids in oncology are mainly dependent on their pro-apoptotic action to treat lymphoproliferative disorders, and also on ...
Kai-Ti Lin, Lu‐Hai Wang
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Effects of Intrauterine Exposure to Synthetic Glucocorticoids on Fetal, Newborn, and Infant Hypothalamic-Pituitary-Adrenal Axis Function in Humans: A Systematic Review [PDF]
Endocrine Reviews, 2009 BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
Marion Tegethoff +2 more
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Metabolites, 2023 The main glucocorticoids involved in the stress response are cortisol and cortisone in most mammals and corticosterone in birds and rodents. Therefore, these analytes are currently the biomarkers more frequently used to evaluate the physiological ...
Maria Botia +2 more
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Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword
Cells, 2013 First described for their metabolic and immunosuppressive effects, glucocorticoids are widely prescribed in clinical settings of inflammation. However, glucocorticoids are also potent inducers of apoptosis in many cell types and tissues. This review will
John A Cidlowski, Cidlowski John A
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Molecules, 2023 Glucocorticoids are classified in section S9 of the Prohibited List of the World Anti-Doping Agency, due to a potential risk to improving physical performance and causing harm to the health of athletes.
Yuqi Ge +3 more
doaj +1 more source
Frontiers in Medicine, 2022 Glucocorticoids are commonly used to treat anti-GBM crescentic glomerulonephritis, however, the mechanism underlying its therapeutic effectiveness is not completely understood.
Xiaomei Wu +8 more
doaj +1 more source
Association between perioperative glucocorticoids and cancer metastasis and survival in patients undergoing radical cystectomy for urothelial carcinoma of the bladder: A single-center retrospective study [PDF]
Investigative and Clinical Urology, 2020 Purpose: Perioperative glucocorticoids have the potential to increase the risk of tumor metastasis. However, the relationship between perioperative glucocorticoids and oncologic outcomes remains controversial. The present study was undertaken to evaluate
Shiyu Mao +8 more
doaj +1 more source
The different roles of glucocorticoids in the hippocampus and hypothalamus in chronic stress-induced HPA axis hyperactivity. [PDF]
PLoS ONE, 2014 Hypothalamus-pituitary-adrenal (HPA) hyperactivity is observed in many patients suffering from depression and the mechanism underling the dysfunction of HPA axis is not well understood.
Li-Juan Zhu +11 more
doaj +1 more source
Confounding by indication probably distorts the relationship between steroid use and cardiovascular disease in rheumatoid arthritis: results from a prospective cohort study. [PDF]
PLoS ONE, 2014 OBJECTIVE: To evaluate the risk of cardiovascular disease in patients with rheumatoid arthritis exposed to glucocorticoids. METHODS: Retrospective analysis of exposure to glucocorticoids in a prospective cohort of 353 patients with rheumatoid arthritis ...
Alper M van Sijl +3 more
doaj +1 more source