Bioconversion of Corticosterone into Corticosterone-Glucoside by Glucosyltransferase [PDF]
Molecules, 2018 Glucosylation of the 21-hydroxyl group of glucocorticoid changes its solubility into hydrophilicity from hydrophobicity and, as with glucocorticoid glucuronides as a moving object in vivo, it is conceivable that it exhibits the same behavior.
Tokutaro Yamaguchi +5 more
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Direct measurement of free glucocorticoids in small volumes of mouse and rat serum using ultrafiltration and liquid chromatography-tandem mass spectrometry. [PDF]
PLoS ONEGlucocorticoids are critical steroid hormones secreted from the adrenal glands. In mice and rats, over 90% of circulating corticosterone is bound to proteins such as corticosteroid-binding globulin and albumin, and the rest is unbound (free).
Anna Mazurenko +2 more
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Effects of corticosterone pellets on baseline and stress-induced corticosterone and corticosteroid-binding-globulin [PDF]
General and Comparative Endocrinology, 2009 Exogenous administration of glucocorticoids is a widely used and efficient tool to investigate the effects of elevated concentrations of these hormones in field studies. Because the effects of corticosterone are dose and duration-dependent, the exact course of plasma corticosterone levels after exogenous administration needs to be known.
Bettina Almasi +2 more
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Frontiers in Ecology and Evolution, 2022 In the current context of global change, there is evidence of a large inter-individual variability in the way animals physiologically respond to anthropogenic changes.
Frédéric Angelier +5 more
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Role of corticosterone on sleep homeostasis induced by REM sleep deprivation in rats. [PDF]
PLoS ONE, 2013 Sleep is regulated by humoral and homeostatic processes. If on one hand chronic elevation of stress hormones impair sleep, on the other hand, rapid eye movement (REM) sleep deprivation induces elevation of glucocorticoids and time of REM sleep during the
Ricardo Borges Machado +2 more
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A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function
Molecular Metabolism, 2021 Objective: Brown adipose tissue (BAT) displays a strong circadian rhythm in metabolic activity, but it is unclear how this rhythm is regulated. As circulating levels of corticosterone coincide with the rhythm of triglyceride-derived fatty acid (FA ...
Jan Kroon +19 more
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The human fetus preferentially secretes corticosterone, rather than cortisol, in response to intra-partum stressors. [PDF]
PLoS ONE, 2013 CONTEXT: Fetal stress is relevant to newborn outcomes. Corticosterone is rarely quantified in human clinical endocrinology and is found at much lower concentrations than cortisol.
Katherine E Wynne-Edwards +2 more
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Delayed effects of corticosterone on slow after-hyperpolarization potentials in mouse hippocampal versus prefrontal cortical pyramidal neurons. [PDF]
PLoS ONE, 2014 The rodent stress hormone corticosterone changes neuronal activity in a slow and persistent manner through transcriptional regulation. In the rat dorsal hippocampus, corticosterone enhances the amplitude of calcium-dependent potassium currents that cause
Anup G Pillai +3 more
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Inhibition of proliferation, migration and proteolysis contribute to corticosterone-mediated inhibition of angiogenesis. [PDF]
PLoS ONE, 2012 The angiostatic nature of pharmacological doses of glucocorticoid steroids is well known. However, the consequences of pathophysiological elevation of endogenous glucocorticoids are not well established.
Eric A Shikatani +9 more
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Corticosterone Can Be an Essential Stress Index in Channel Catfish (Ictalurus punctatus)
Frontiers in Marine Science, 2021 Although cortisol is considered the main glucocorticoid involved in regulating stress in fish by elevating the serum glucose, the presence of serum corticosterone and whether its level can be used as an indicator for fish stress activation and reflect ...
Kang Xiao +17 more
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