Results 1 to 10 of about 258,084 (317)
Case Report: Afatinib-Induced Interstitial Pneumonia: Experiences and Lessons From Two Patients
Frontiers in Pharmacology, 2021 Background: Afatinib has shown good efficacy in patients harboring uncommon EGFR mutations, but the incidence of afatinib-induced interstitial pneumonia should be alert as its rapid progression.
Xiao Liu +3 more
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Glucocorticoids in rheumatoid arthritis: current status and future studies
RMD Open, 2020 Since their first use for treating rheumatoid arthritis (RA) in the late 1940s, glucocorticoids (GCs) have been representing a substantial part of the therapeutic arsenal for RA.
Frank Buttgereit +2 more
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SEVERE METABOLIC DISORDER – CAUSE OF DEATH AT A NEWBORN SUFFERING FROM CHRONIC CONDITION [PDF]
Romanian Journal of Pediatrics, 2017 Congenital adrenal hyperplasia is an autosomal recessive disorder of adrenal steroid biosynthesis, children born from consanguinity relationships have the highest burden of disease.
Roxana Tanase +5 more
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Medicina, 2021 Background and Objectives: The present study investigated the beneficial effects of tart cherry (fruit of Prunus cerasus) concentrated powder (TCcp) on glucocorticoid (GLU)-induced catabolic muscular atrophy in the skeletal muscle of mice.
Sae-Kwang Ku +5 more
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Pharmacology Research & Perspectives, 2023 Glucocorticoid excess adversely affects male reproduction. This study evaluates effects of pharmacological doses of niacin on testicular structure and function in dexamethasone‐treated rats.
E. Azimi Zangabad +2 more
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Brain Sciences, 2021 We examined whether chewing behavior affects the tumor progression-enhancing impact of psychological stress. Human breast cancer cell line (MDA-MB-231) cells were inoculated into the mammary fat pads of athymic nude mice.
Qian Zhou +7 more
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Glucocorticoids and lymphocytes. III. Effects of glucocorticoid administration on lymphocyte glucocorticoid receptors [PDF]
Blood, 1983 Abstract To determine the effects of glucocorticoid administration on the number of measured lymphocyte glucocorticoid receptor sites and the duration of such effects, seven normal volunteers were studied. Glucocorticoid receptor levels of the lymphocytes circulating in the blood of each volunteer were determined. Glucocorticoid was then
G F, Shipman +4 more
openaire +3 more sources
GILZ as a Regulator of Cell Fate and Inflammation
Cells, 2021 One of the human body’s initial responses to stress is the adrenal response, involving the release of mediators that include adrenaline and glucocorticoids (GC). GC are involved in controlling the inflammatory and immune response mechanisms.
Stefano Bruscoli +2 more
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Glucocorticoids in Sepsis: To Be or Not to Be
Frontiers in Immunology, 2020 Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic responses to infection, thereby compromising host homeostasis. Activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequently adrenocortical glucocorticoid (GC) production during sepsis are important regulatory processes to maintain homeostasis.
Jolien Vandewalle +3 more
openaire +4 more sources
Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies
OncoImmunology, 2020 Glucocorticoids mediate potent anti-inflammatory and immunosuppressive effects. A chronic elevation of the endogenous glucocorticoid tonus subsequent to mental stress, as well as continuous treatment with exogenous glucocorticoids, activate an ...
Yuting Ma, Heng Yang, Guido Kroemer
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