Results 31 to 40 of about 287,841 (259)

Type 1 interferon suppresses expression and glucocorticoid induction of glucocorticoid-induced leucine zipper (GILZ)

Frontiers in Immunology, 2022
SLE is a systemic multi-organ autoimmune condition associated with reduced life expectancy and quality of life. Glucocorticoids (GC) are heavily relied on for SLE treatment but are associated with detrimental metabolic effects.
Wendy Dankers, Melissa Northcott, Taylah Bennett, Akshay D’Cruz, Rochelle Sherlock, Linden J. Gearing, Paul Hertzog, Brendan Russ, Iolanda Miceli, Sebastian Scheer, Maki Fujishiro, Kunihiro Hayakawa, Keigo Ikeda, Keigo Ikeda, Eric F. Morand, Sarah A. Jones   +15 more
doaj   +1 more source

Phenotypic characteristics of familial glucocorticoid deficiency (FGD) type 1 and 2 [PDF]

, 2010
Context: Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disorder as a result of mutation in genes encoding either the ACTH receptor [melanocortin 2 receptor (MC2R)] or its accessory protein [melanocortin 2 receptor accessory ...
Metherell, LA, Chung, TTLL, Clark, AJ, Chung, TT, Chan, LF, Clark, AJL   +5 more
core   +1 more source

Methodological considerations in the analysis of fecal glucocorticoid metabolites in tufted capuchins (Cebus apella) [PDF]

, 2013
Analysis of fecal glucocorticoid (GC) metabolites has recently become the standard method to monitor adrenocortical activity in primates noninvasively. However, given variation in the production, metabolism, and excretion of GCs across species and even ...
Wheeler, Brandon C., Michael Heistermann, Tiddi, Barbara, Brandon C. Wheeler, Heistermann, M., Tiddi, B., Kalbitzer, U., Visalberghi, E., Wheeler, Brandon C, Visalberghi, Elisabetta, Heistermann, Michael, Wheeler, B., Elisabetta Visalberghi, Urs Kalbitzer, Kalbitzer, Urs, Barbara Tiddi, Kalbitzer Urs, Wheeler Brandon C, Tiddi Barbara, Visalberghi Elisabetta, Heistermann Michael   +20 more
core   +1 more source

Piper sarmentosum Effects on 11β-Hydroxysteroid Dehydrogenase Type 1 Enzyme in Serum and Bone in Rat Model of Glucocorticoid-Induced Osteoporosis

Molecules, 2016
Glucocorticoid-induced osteoporosis is one of the common causes of secondary osteoporosis. Piper sarmentosum (Ps) extract possesses antioxidant and anti-inflammatory activities.
Siti Fadziyah Mohamad Asri, Elvy Suhana Mohd Ramli, Ima Nirwana Soelaiman, Muhamad Alfakry Mat Noh, Abdul Hamid Abdul Rashid, Farihah Suhaimi   +5 more
doaj   +1 more source

Clinical Features of Hypersensitivity Pneumonitis in Children: A Single Center Study

Frontiers in Pediatrics, 2022
BackgroundHypersensitivity pneumonia (HP) is an interstitial lung disease (ILD) mainly involving small airways and lung parenchyma that is caused by the inhalation of antigens in susceptible people to stimulate the body's immune response.MethodsA total ...
Feizhou Zhang, Tongyu Yang, Zhixuan Liu, Xuan Jia, Li Yang, Lei Wu, Lanfang Tang   +6 more
doaj   +1 more source

Investigating crosstalk in lipid rafts between the glucocorticoid receptor and gonadotropin-releasing hormone receptor signaling pathways in a gonadotrope cell line [PDF]

, 2010
Includes abstract.Includes bibliographical references (leaves 121-158).A recent study from the Hapgood laboratory demonstrated the presence of a novel crosstalk mechanism between the glucocorticoid receptor (GR) and gonadotropin-releasing hormone ...
Wehmeyer, Lance
core   +1 more source

Mode of Glucocorticoid Actions in Airway Disease [PDF]

, 2006
Synthetic glucocorticoids are the most potent anti-inflammatory agents used to treat chronic inflammatory disease, such as asthma. However, a small number (
Charron, C.E., Ito, K., Kazuhiro Ito, Steve Getting, Catherine Charron, Getting, S.J.   +5 more
core   +2 more sources

Therapeutic Penetrating Keratoplasty in a Case of Corneal Perforation Caused by Colletotrichum gloeosporioides Infection

Pathogens, 2022
Background: Corneal infection of Colletotrichum gloeosporioides is uncommon and usually limited to the anterior stroma. However, we observed a case of corneal stromal perforation caused by this fungus under a compromised condition.
Kazuki Imai, Takayoshi Sumioka, Hiroki Iwanishi, Yukihisa Takada, Shin’ichi Murata, Ryuta Iwamoto, Yuka Okada, Shizuya Saika   +7 more
doaj   +1 more source

Selective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitro [PDF]

, 2012
Introduction: Despite the excellent anti-inflammatory and immunosuppressive action of glucocorticoids (GCs), their use for the treatment of inflammatory bowel disease (IBD) still carries significant risks in terms of frequently occurring severe side ...
Kerstin C Reuter, Jürgen Stein, Axel U Dignass, Stefan M Loitsch, Dieter Steinhilber (182458), Reuter, Kerstin C., Dignaß, Axel Uwe, Kerstin C. Reuter (186426), Dieter Steinhilber, Stefan M. Loitsch (186433), Loitsch, Stefan Marcel, Stein, Jürgen, Axel U. Dignass (186440), Steinhilber, Dieter, Jürgen Stein (186447)   +14 more
core   +2 more sources

Diagnosis and treatment of transnasal endoscopic optic canal decompression for traumatic optic neuropathy

Frontiers in Neuroscience, 2023
ObjectiveTo investigate the clinical efficacy and prognostic factors of transnasal endoscopic optic decompression in the treatment of traumatic optic neuropathy (TON).MethodsA retrospective analysis was performed on 13 TON patients in The Seventh ...
Xiang Tu, Cheng Xiong, Hui Qi, Yangming Ou, Jing Rao, Yueqi Sun, Yunping Fan, Guiqin Liu   +7 more
doaj   +1 more source