Results 41 to 50 of about 310,312 (350)

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System

Frontiers in Immunology, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
C. Strehl, L. Ehlers, T. Gaber, F. Buttgereit   +3 more
semanticscholar   +1 more source

Fibrotic pathways and fibroblast-like synoviocyte phenotypes in osteoarthritis

Frontiers in Immunology
Osteoarthritis (OA) is the most common form of arthritis, characterized by osteophyte formation, cartilage degradation, and structural and cellular alterations of the synovial membrane.
Alexandra Damerau, Alexandra Damerau, Emely Rosenow, Dana Alkhoury, Frank Buttgereit, Frank Buttgereit, Timo Gaber, Timo Gaber   +7 more
doaj   +1 more source

Trends and Patterns of Systemic Glucocorticoid Prescription in Primary Care Institutions in Southwest China, from 2018 to 2021

Risk Management and Healthcare Policy, 2023
Xiaoyi Li,1,* Zhen Zeng,2,* Xingying Fan,1,3 Wenju Wang,4 Xiaobo Luo,4 Junli Yang,1 Yue Chang1,3,* 1School of Medicine and Health Management, Guizhou Medical University, Guiyang, Guizhou Province, People’s Republic of China; 2Second ...
Li X, Zeng Z, Fan X, Wang W, Luo X, Yang J, Chang Y   +6 more
doaj  

Glucocorticoids Inhibit Sodium Depletion-induced Salt Appetite in Rat

, 2010
Glucocorticoids, produced in adrenal cortex, exert potent natriuretic and diuretic actions in the kidney. Recently, it has been found that glucocorticoids could upregulate the expression of natriuretic peptide receptor A (NPR-A), the primary receptor of ...
Chao Liu, Kunshen Liu, Jing Guan, Ying Chen   +3 more
core   +1 more source

Glucocorticoids Suppress Antimicrobial Autophagy and Nitric Oxide Production and Facilitate Mycobacterial Survival in Macrophages

Scientific Reports, 2017
Chronic administration of glucocorticoids has been shown to render individuals highly susceptible to mycobacterial infection and lead to reactivation of latent bacilli.
Jinli Wang, Ruining Wang, Hui Wang, Xiaofan Yang, Jiahui Yang, Wenjing Xiong, Qian Wen, Li Ma   +7 more
doaj   +1 more source

High‐dose glucocorticoids for the treatment of ipilimumab‐induced hypophysitis is associated with reduced survival in patients with melanoma

Cancer, 2018
It remains unclear whether high doses of glucocorticoids have a negative impact on the efficacy of checkpoint inhibitors. To control for the potential association between immune‐related adverse events (irAEs) and improved survival, this study examined a ...
A. Faje, D. Lawrence, K. Flaherty, C. Freedman, Riley M. Fadden, Krista M. Rubin, J. Cohen, R. Sullivan   +7 more
semanticscholar   +1 more source

Life Course Impact of Glucocorticoids During Pregnancy on Muscle Development and Function

Frontiers in Animal Science, 2021
Maternal stress, such as maternal obesity, can induce severe gestational disease and hormonal disorder which may disrupt fetal organ maturation and further cause endangered early or future health in offspring.
Yang Liu, Qiyue Ding, Wei Guo
doaj   +1 more source

Glucocorticoids and resilience [PDF]

Hormones and Behavior, 2019
All organisms endure frequent challenges to homeostasis, or stressors, that require adaptation. Depending on the individual, the context, and the magnitude of stress, this active adaptation can lead to behavioral susceptibility or resilience. The latter is an under-appreciated consequence of stress, as the damaging effects of chronic stress and ...
Joanna L, Spencer-Segal, Huda, Akil
openaire   +2 more sources

Impacts of different methylprednisolone administration routes in patients with sudden hearing loss or Meniere’s disease

Journal of Otology, 2020
Background: Evidence suggests that glucocorticoids are important in the treatment of sudden hearing loss (SHL) and Meniere’s disease (MD). However, different glucocorticoid administration methods may have a significant impact on treatment outcomes ...
Dan Chen, Zhipeng Li, Qilin Zhou, Yubin Chen, Luoying Yang, Jingqian Tan, Xiangli Zeng, Peng Li   +7 more
doaj   +1 more source

Glucocorticoids act on glutamatergic pathways to affect memory processes [PDF]

Glucocorticoids can acutely affect memory processes, with both facilitating and impairing effects having been described. Recent work has revealed that glucocorticoids may affect learning and memory processes by interacting with glutamatergic mechanisms ...
Sandi, Carmen
core   +1 more source