Results 11 to 20 of about 241,090 (306)

Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthma [PDF]

Mediators of Inflammation, 1998
Glucocorticoids are potent inhibitors of inflammatory processes and are widely used in the treatment of asthma. The anti-inflammatory effects are mediated either by direct binding of the glucocorticoid/glucocorticoid receptor complex to glucocorticoid ...
V. H. J. van der Velden
doaj   +2 more sources

Inhaled glucocorticoids and COPD exacerbations [PDF]

, 2015
Inhaled glucocorticoids and COPD ...
I. D. Pavord (7605032), M. Bafadhel (7634756), Christopher E. Brightling (7165121)   +2 more
core   +4 more sources

Glucocorticoids Inhibit Sodium Depletion-induced Salt Appetite in Rat [PDF]

, 2010
Glucocorticoids, produced in adrenal cortex, exert potent natriuretic and diuretic actions in the kidney. Recently, it has been found that glucocorticoids could upregulate the expression of natriuretic peptide receptor A (NPR-A), the primary receptor of ...
Chao Liu, Kunshen Liu, Jing Guan, Ying Chen   +3 more
core   +1 more source

Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]

, 2005
Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Korting, Hans Christian, Schäfer-Korting, Monika, Kleuser, B., Ahmed, M., Holtje, H. D.   +4 more
core   +1 more source

Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review [PDF]

, 2009
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
Pryce, C R, Meinlschmidt, G., Meinlschmidt, M, Tegethoff, M., Pryce, C., Tegethoff, M, Christopher Pryce, Gunther Meinlschmidt, Marion Tegethoff, Tegethoff M, Meinlschmidt G, Pryce C   +11 more
core   +1 more source

Determinants of the protective effect of glucocorticoids on mortality in hospitalized patients with COVID-19

International Journal of Infectious Diseases, 2021
Background: Glucocorticoid therapy has emerged as an effective therapeutic option in hospitalized patients with coronavirus disease 2019 (COVID-19). This study aimed to focus on the impact of relevant clinical and laboratory factors on the protective ...
Matteo Pagnesi, Riccardo M. Inciardi, Carlo M. Lombardi, Piergiuseppe Agostoni, Pietro Ameri, Lucia Barbieri, Antonio Bellasi, Rita Camporotondo, Claudia Canale, Valentina Carubelli, Stefano Carugo, Francesco Catagnano, Laura A. Dalla Vecchia, Gian Battista Danzi, Mattia Di Pasquale, Margherita Gaudenzi, Stefano Giovinazzo, Massimiliano Gnecchi, Marco Guazzi, Annamaria Iorio, Maria Teresa La Rovere, Sergio Leonardi, Gloria Maccagni, Massimo Mapelli, Davide Margonato, Marco Merlo, Luca Monzo, Andrea Mortara, Vincenzo Nuzzi, Massimo Piepoli, Italo Porto, Andrea Pozzi, Filippo Sarullo, Gianfranco Sinagra, Chiara Tedino, Daniela Tomasoni, Maurizio Volterrani, Gregorio Zaccone, Michele Senni, Marco Metra   +39 more
doaj   +1 more source

MAPK phosphatase-1 represents a novel antiinflammatory target of glucocorticoids in the human endothelium [PDF]

, 2007
Glucocorticoids are well-established anti- inflammatory drugs thought to mainly act by inhibition of proinflammatory transcription factors like NF-κB.
Timm Schroeder, Stefan Zahler, Eilken, H.M., Bubik, M.F., Vollmar, Angelika M., Alexandra K. Kiemer, Kiemer, Alexandra K., Zahler, S., Fürst, Robert, Robert Fürst, Schroeder, Timm, Martin F. Bubik, Angelika M. Vollmar, Hanna M. Eilken, Vollmar, A.M., Eilken, Hanna M., Fürst, R., Bubik, Martin F., Zahler, Stefan, Schroeder, T., Kiemer, A.K.   +20 more
core   +1 more source

Endogenous glucocorticoids in inflammation: contributions of systemic and local responses

Swiss Medical Weekly, 2012
The anti-inflammatory actions of therapeutic glucocorticoids are well established and these drugs are widely used to treat a variety of inflammatory conditions.
Rowan S. Hardy, Karim Raza, Mark S. Cooper   +2 more
doaj   +1 more source

Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells [PDF]

, 2012
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a key transcription factor regulating a plethora of detoxifying enzymes and antioxidant genes involved in drug metabolism and defence against oxidative stress.
Denise V. Kratschmar (165140), Diego Calabrese, Diego Calabrese (165146), Moulin, Pierre, Birk, Julia, Pierre Moulin, Appenzeller-Herzog, Christian, Calabrese, Diego, Christian Appenzeller-Herzog (165171), Lister Adam, Lister, Adam, Alex Odermatt (27423), Pierre Moulin (106353), Adam Lister (165158), Walsh Jo, Appenzeller-Herzog Christian, Moulin Pierre, Goldring Chris E., Chris E. Goldring (165179), Birk Julia, Jo Walsh, Jo Walsh (165152), Chris E Goldring, Kratschmar, Denise V., Denise V Kratschmar, Calabrese Diego, Goldring, Chris E., Kratschmar Denise V., Walsh, Jo, Julia Birk, Julia Birk (165165), Alex Odermatt, Odermatt Alex, Adam Lister, Odermatt, Alex, Christian Appenzeller-Herzog, Appenzeller-Herzog C, Birk J, Goldring CE, Odermatt A, Lister A, Kratschmar DV, Walsh J, Moulin P, Calabrese D   +44 more
core   +2 more sources

Glucocorticoids and cortical decoding in the phobic brain. [PDF]

, 2020
Glucocorticoids reduce phobic fear in anxiety disorders and enhance psychotherapy, possibly by reducing the retrieval of fear memories and enhancing the consolidation of new corrective memories.
Nakataki, Masahito, Heinrichs, Markus, Soravia, Leila M., Quervain, Dominique J.-F. de, Wiest, Roland, de Quervain, Dominique, Soravia, Leila Maria, Schwab, Simon, Federspiel, Andrea, Morishima, Yosuke, Strik, Werner, Nakataki M, Federspiel A, Strik W, Schwab S, Soravia LM, Heinrichs M, Wiest R, de Quervain D, Morishima Y   +19 more
core   +1 more source