Results 101 to 110 of about 15,631 (257)

Inhaled corticosteroids versus long-acting beta -agonists for chronic obstructive pulmonary disease (Review). [PDF]

open access: yes, 2011
Long-acting beta(2)-agonists and inhaled corticosteroids can be used as maintenance therapy by patients with moderate to severe chronic obstructive pulmonary disease. These interventions are often taken together in a combination inhaler.
Agarwal   +105 more
core   +2 more sources

Mechanistic Physiologically Based Pharmacokinetic Modeling of Dry Powder and Nebulized Formulations of Orally Inhaled TMEM16A Potentiator GDC‐6988

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 6, Page 1087-1097, June 2025.
ABSTRACT The orally inhaled route of administration for respiratory indications can maximize drug exposure to the site of action (lung) to increase efficacy while minimizing systemic exposure to achieve an improved safety profile. However, due to the difficulty of taking samples from different regions of the human lung, often only systemic ...
Rui Zhu   +12 more
wiley   +1 more source

Effects of Nebulized Albuterol in Transient Tachypnea of the Newborn A Clinical Trial

open access: yes, 2017
Background: To date there is no effective drug treatment for transient tachypnea of the newborn (TTN) and respiratory support is the only means to handle this disease.
Mirhadi Mussavi   +3 more
semanticscholar   +1 more source

Using an Audience Response System Smartphone App to Improve Resident Education in the Pediatric Intensive Care Unit. [PDF]

open access: yes, 2018
In the Pediatric Intensive Care Unit (PICU), most teaching occurs during bedside rounds, but technology now provides new opportunities to enhance education. Specifically, smartphone apps allow rapid communication between instructor and student.
Anas, Nick   +7 more
core   +2 more sources

Exhaled Breath Condensate Detects Baseline Reductions in Chloride and Increases in Response to Albuterol in Cystic Fibrosis Patients

open access: yesClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2013
Impaired ion regulation and dehydration is the primary pathophysiology in cystic fibrosis (CF) lung disease. A potential application of exhaled breath condensate (EBC) collection is to assess airway surface liquid ionic composition at baseline and in ...
Courtney M. Wheatley   +7 more
doaj   +1 more source

Adverse Outcomes Associated With Short‐Acting Beta‐Agonist Overuse in Asthma: A Systematic Review and Meta‐Analysis

open access: yesAllergy, Volume 80, Issue 6, Page 1629-1646, June 2025.
ABSTRACT Introduction The 2019 Global Initiative for Asthma (GINA) report no longer recommended short‐acting beta‐agonists (SABA) monotherapy due to associated complications and a lack of anti‐inflammatory properties. This systematic review and meta‐analysis aimed to evaluate adverse outcomes associated with SABA overuse in patients with asthma ...
Chia‐Ling Tsao   +6 more
wiley   +1 more source

Excessive gas exchange impairment during exercise in a subject with a history of bronchopulmonary dysplasia and high altitude pulmonary edema [PDF]

open access: yes, 2007
A 27-year-old male subject (V(O2 max)), 92% predicted) with a history of bronchopulmonary dysplasia (BPD) and a clinically documented case of high altitude pulmonary edema (HAPE) was examined at rest and during exercise.
Andrew T. Lovering   +6 more
core   +1 more source

Obesity: Next game changer of allergic airway diseases?

open access: yesClinical and Translational Medicine, Volume 15, Issue 5, May 2025.
Obesity affects various aspects of allergic airway diseases, including prevalence, endotypes, clinical features and therapeutic efficacy. Therefore, obesity‐related allergic airway diseases represent a unique class of endotypes and phenotypes, which need much more in‐depth research for tailored treatment.
Wenlong Li   +4 more
wiley   +1 more source

Management of hyperkalemia in the acutely ill patient. [PDF]

open access: yes, 2019
PURPOSE:To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients. METHODS:We searched MEDLINE and EMBASE for relevant papers published in English between Jan 1, 1938, and July 1,
Dépret, François   +5 more
core   +3 more sources

Congenital myasthenic syndrome in Golden Retrievers is associated with a novel COLQ mutation. [PDF]

open access: yes, 2020
BackgroundCongenital myasthenic syndromes (CMSs) are a group of inherited disorders of neuromuscular transmission that may be presynaptic, synaptic, or postsynaptic.
Anderson, Kendall J   +11 more
core  

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