Results 1 to 10 of about 44,370 (261)

Improvements With Tiotropium Maintenance Therapy in COPD Patients Without Dyspnea. [PDF]

MedComm (2020)
In a post hoc analysis of the Tie‐COPD trial, including 305 patients with mild‐to‐moderate COPD and no dyspnea (mMRC 0), 2 years of tiotropium improved lung function, lowered the annual exacerbation rate, and delayed the first clinically important deterioration, indicating benefit beyond symptom relief in a group not currently offered maintenance ...
Wang Z, Lin J, Cai G, Wu F, Deng Z, Wan Q, Tang G, Dai C, Lu L, Zhou K, Wu X, Huang S, Wu F, Zhong N, Zhou Y, Ran P.   +15 more
europepmc   +2 more sources

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies. [PDF]

Eur J Clin Invest
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Raman S, Rahman S, Polverino F, Adrish M.   +3 more
europepmc   +2 more sources

Defining the optimal spirometry cut-off points for optimal bronchodilator response in prematurity-associated lung disease. [PDF]

ERJ Open Res
Lowe J, Cousins M, Hart K, Kotecha SJ, Watkins WJ, Kotecha S.   +5 more
europepmc   +1 more source

Associations of current and life-course smoking and indoor environmental exposures with lung function level in early adulthood. [PDF]

Environ Epidemiol
Hendrickx DM, Koppelman GH, Vonk JM, Boer JMA, Koefoed HJL, Oldenwening M, Vermeulen RCH, Gehring U.   +7 more
europepmc   +1 more source

Effectiveness of Continuous Levalbuterol Versus Albuterol During a National Shortage: A Retrospective Observational Cohort Study. [PDF]

Pediatr Pulmonol
Tank A, Silver L, Spaeder MC, Rogerson C, Shanklin A.   +4 more
europepmc   +1 more source

Body mass index, lung function, and FeNO in children with positive bronchodilator response: a cross-sectional study. [PDF]

Front Pediatr
Zhou T, Liu J, Lin Y, Zhang G, Chen Y, Liu X, Guo J, Wu X.   +7 more
europepmc   +1 more source

Long term outcome following pulmonary TB or lower respiratory tract illness in children: a prospective South African study. [PDF]

EClinicalMedicine
Chaya S, Githinji L, Marozva N, Workman L, Franckling-Smith Z, McFarlane D, James N, Prins M, Nicol MP, Gray DM, Zar HJ.   +10 more
europepmc   +1 more source

Pre-COPD, PRISm, and COPD in young adults born preterm. [PDF]

Ann Am Thorac Soc
Smith EF, Lavery C, Simpson SJ.
europepmc   +1 more source

Diagnostic and Therapeutic Challenges in Asthma and Chronic Obstructive Pulmonary Disease Overlap: A Four-Patient Case Series. [PDF]

Cureus
Amalraj B, Marrero Castillo M, Gulati N.
europepmc   +1 more source

Impaired lung function and bronchodilator responsiveness in former very preterm infants at preschool age: associated factors and clinical implications. [PDF]

Front Pediatr
Höck M, Zschocke A, Pupp Peglow U, Staudt A, Marcher C, Schütz M, Kofler M, Gaaß K, Brunner B, Kiechl-Kohlendorfer U, Griesmaier E.   +10 more
europepmc   +1 more source