Results 21 to 30 of about 44,370 (261)

Changing patterns in long-acting bronchodilator trials in chronic obstructive pulmonary disease. [PDF]

, 2011
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Developments in the understanding of COPD have led to standard guidelines for diagnosis, treatment, and spirometry assessments, which have in turn ...
James Donohue, Paul Jones, James F Donohue, Paul W Jones, Donohue, JF, Jones, PW   +5 more
core   +1 more source

Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation

Molecules, 2022
Oxidative stress is the key factor that strengthens free radical generation which stimulates lung inflammation. The aim was to explore antioxidant, bronchodilatory along with anti-asthmatic potential of folkloric plants and the aqueous methanolic crude ...
Taha Alqahtani, Sajida Parveen, Yahia Alghazwani, Hanan M. Alharbi, Reem M. Gahtani, Nadia Hussain, Kashif ur Rehman, Musaddique Hussain   +7 more
doaj   +1 more source

Bronchodilator reversibility testing in chronic obstructive pulmonary disease.

, 2003
A limited or absent bronchodilator response is used to classify chronic obstructive pulmonary disease (COPD) and can determine the treatment offered. The reliability of the recommended response criteria and their relationship to disease progression has ...
Spencer, Sally, Calverley, Peter MA, Jones, Paul W, Burge, P Sherwood, Anderson, Julie A   +4 more
core   +5 more sources

Bronchodilator reversibility in patients with COPD revisited: short-term reproducibility [PDF]

, 2016
Steven Pascoe,1 Wei Wu,2 Chang-Qing Zhu,3 Dave Singh4 1GSK, Respiratory Medicines Development Center, 2PAREXEL International, Research Triangle Park, NC, USA; 3GSK, Clinical Statistics (Respiratory), Middlesex, UK; 4Medicines Evaluation Unit, University
Pascoe S, Zhu CQ, Wu W, Singh D
core   +2 more sources

Bronchodilatory and B-adrenergic effects of methanolic and aqueous extracts of Althaea root on isolated tracheobronchial smooth rat muscle

Advanced Biomedical Research, 2015
Background: The smooth muscle contractions of the tracheobronchial airways are mediated through the balance of adrenergic, cholinergic and peptidergic nervous mechanisms.
Behrang Alani, Mohammad Zare, Mahdi Noureddini   +2 more
doaj   +1 more source

Triple Therapy of Fluticasone Furoate, Umeclidinium, Vilanterol- A Compelling Choice in Severe Chronic Obstructive Pulmonary Disease [PDF]

Journal of Clinical and Diagnostic Research, 2021
Trelegy Ellipta (GlaxoSmithKlineTM) is the first single inhaler triple combination therapy comprising of umeclidinium, vilanterol and fluticasone approved by the United States Food and Drug Administration (US FDA) for patients with severe COPD in 2019.
B Jagan Nathan, Melina I Sahay, AK Gautham, DK Sriram, Melvin George   +4 more
doaj   +1 more source

Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts

Frontiers in Pharmacology, 2019
Background: Interleukin (IL)-26 is a neutrophil-mobilizing and bactericidal cytokine that is enhanced in human airways in vivo in response to endotoxin from Gram-negative bacteria.
Karlhans Fru Che, Jitong Sun, Jitong Sun, Anders Linden, Anders Linden   +4 more
doaj   +1 more source

Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial [PDF]

, 2000
Objectives To determine the effect of long term inhaled corticosteroids on lung function, exacerbations, and health status in patients with moderate to severe chronic obstructive pulmonary disease.
Spencer, S, Spencer, Sally, Calverley, Peter MA, Jones, Paul W, Jones, PW, Maslen, TK, Burge, P Sherwood, Burge, PS, Calverley, PMA, Maslen, T K, Anderson, JA, Spencer, Sally; id_orcid, Anderson, Julie A   +12 more
core   +1 more source

Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study [PDF]

, 2009
Background: The efficacy of inhaled salmeterol plus fluticasone propionate (SFC) in patients with severe or very severe COPD is well documented. However, there are only limited data about the influence of GOLD severity staging on the effectiveness of ...
Jones, Paul W, Yates, Julie C, Jones, PW, Yates Julie C, Vestbo Jörgen, Jenkins, Christine R, Willits, LR, Celli Bartolome, Willits Lisa R, Anderson, Julie A., Calverley, PMA, Calverley, PM, Willits, Lisa R., Julie A Anderson, Jörgen Vestbo, Anderson Julie A, Yates, JC, Calverley Peter MA, Anderson, JA, Vestbo, Jörgen, Jones Paul W, Ferguson Gary T, Christine R Jenkins, Jenkins, CR, Ferguson, GT, Gary T Ferguson, Anderson, Julie A, Vestbo, Jorgen; id_orcid, Celli, Bartolome, Bartolome Celli, Peter MA Calverley, Lisa R Willits, Ferguson, Gary T., Calverley, Peter M A, Ferguson, Gary T, Vestbo, J, Jenkins Christine R, Jenkins, CR ; https://orcid.org/, Celli, B, Paul W Jones, Jones, Paul W., Jenkins, Christine R., Julie C Yates, Willits, Lisa R, Yates, Julie C.   +44 more
core   +2 more sources

Something Is Changing in Viral Infant Bronchiolitis Approach

Frontiers in Pediatrics, 2022
Acute Viral Bronchiolitis is one of the leading causes of hospitalization in the first 12–24 months of life. International guidelines on the management of bronchiolitis broadly agree in recommending a minimal therapeutic approach, not recommending the ...
Paolo Bottau, Lucia Liotti, Eleonora Laderchi, Alessandra Palpacelli, Elisabetta Calamelli, Carlotta Colombo, Laura Serra, Salvatore Cazzato   +7 more
doaj   +1 more source