Results 21 to 30 of about 68,751 (311)

Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts

Frontiers in Pharmacology, 2019
Background: Interleukin (IL)-26 is a neutrophil-mobilizing and bactericidal cytokine that is enhanced in human airways in vivo in response to endotoxin from Gram-negative bacteria.
Karlhans Fru Che, Jitong Sun, Jitong Sun, Anders Linden, Anders Linden   +4 more
doaj   +1 more source

Comparison of bronchodilator administration with vibrating mesh nebulizer and standard jet nebulizer in the emergency department

American Journal of Emergency Medicine, 2017
Introduction: Projects comparing bronchodilator response by aerosol devices in the ED are limited. Evidence suggests that the vibrating mesh nebulizer (VMN) provides 5‐fold greater aerosol delivery to the lung as compared to a jet nebulizer (JN). The aim
R. Dunne, S. Shortt
semanticscholar   +1 more source

Something Is Changing in Viral Infant Bronchiolitis Approach

Frontiers in Pediatrics, 2022
Acute Viral Bronchiolitis is one of the leading causes of hospitalization in the first 12–24 months of life. International guidelines on the management of bronchiolitis broadly agree in recommending a minimal therapeutic approach, not recommending the ...
Paolo Bottau, Lucia Liotti, Eleonora Laderchi, Alessandra Palpacelli, Elisabetta Calamelli, Carlotta Colombo, Laura Serra, Salvatore Cazzato   +7 more
doaj   +1 more source

COPD: maximization of bronchodilation [PDF]

Multidisciplinary Respiratory Medicine, 2014
The most recent guidelines define COPD in a multidimensional way, nevertheless the diagnosis is still linked to the limitation of airflow, usually measured by the reduction in the FEV1/FVC ratio below 70%. However, the severity of obstruction is not directly correlated to symptoms or to invalidity determined by COPD.
Stefano Nardini, CAMICIOTTOLI, GIANNA, Salvatore Locicero, Rosario Maselli, Franco Pasqua, Giovanni Passalacqua, Riccardo Pela, Alberto Pesci, Alfredo Sebastiani, Alessandro Vatrella   +9 more
openaire   +6 more sources

Bronchodilator response is linked with uncontrolled moderate-to-severe childhood asthma and elevated IL-4 and IL-13. [PDF]

Pediatr Allergy Immunol
High BDR (≥10% FEV1) predicts 3‐fold higher odds of poor asthma control in children with moderate‐to‐severe asthma. High BDR links to elevated T2 cytokines (IL‐4, IL‐13) and non‐T2 mediators (IL‐1β, IL‐6, IL‐7, IL‐8, TNF‐α), as well as MMP‐1. BDR offers non‐invasive phenotyping potential to advance personalized asthma management.
Metwally NKA, Hashimoto S, Vijverberg SJH, Neerincx AH, Dierdorp BS, Dekker T, Haarman EG, Duitman JW, Gorenjak M, Toncheva AA, Harner S, Brandstetter S, Wolff C, Corcuera-Elosegui P, López-Fernández L, Sardón-Prado O, Pino-Yanes M, Potočnik U, Kabesch M, Kraneveld AD, Lutter R, Terheggen-Lagro SWJ, Abdel-Aziz MI, Maitland-van der Zee AH, SysPharmPediA Consortium.   +24 more
europepmc   +2 more sources

The Role of Fixed-Dose Dual Bronchodilator Therapy in Treating COPD.

American Journal of Medicine, 2018
The incidence of chronic obstructive pulmonary disease (COPD) is rising in the United States, and the disease represents a significant source of morbidity and mortality.
A. Anzueto, M. Miravitlles
semanticscholar   +1 more source

Tidal breathing parameters measured using structured light plethysmography in healthy children and those with asthma before and after bronchodilator

Physiological Reports, 2017
Structured light plethysmography (SLP) is a light‐based, noncontact technique that measures tidal breathing by monitoring displacements of the thoracoabdominal (TA) wall.
Hamzah Hmeidi, Shayan Motamedi-Fakhr, E. Chadwick, F. Gilchrist, W. Lenney, R. Iles, Rachel C. Wilson, J. Alexander   +7 more
semanticscholar   +1 more source

Economic Evaluation of an Asthma Therapy: Effect of Salmeterol on Loss of Labor Productivity in Japan

Allergology International, 2005
Background: Asthma can have a negative impact on the productivity of paid and unpaid individuals. In this study, we aimed to investigate the impact of salmeterol, which, in recent years, has become available for the treatment of asthma in Japan, on the ...
Takehiko Miyagawa, Shuzo Nishimura
doaj   +1 more source

Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial [PDF]

, 2000
Objectives To determine the effect of long term inhaled corticosteroids on lung function, exacerbations, and health status in patients with moderate to severe chronic obstructive pulmonary disease.
Spencer, S, Spencer, Sally, Calverley, Peter MA, Jones, Paul W, Jones, PW, Maslen, TK, Burge, P Sherwood, Burge, PS, Calverley, PMA, Maslen, T K, Anderson, JA, Spencer, Sally; id_orcid, Anderson, Julie A   +12 more
core   +1 more source

Assessment of bronchodilator responsiveness to salbutamol or ipratropium using different criteria in treatment-naïve patients with asthma and COPD

European Clinical Respiratory Journal
Background The criteria for significant bronchodilator responsiveness (BDR) were published in 2005 by the European Respiratory Society/American Thoracic Society, which were revised in 2021, however, data on the agreement between these two recommendations
Zsófia Lázár, Alpár Horváth, Szilvia Kiss-Dala, Zsolt Abonyi-Tóth, Balázs Csoma, Katalin Kontz, Lilla Tamási, Veronika Müller   +7 more
doaj   +1 more source