Results 11 to 20 of about 44,370 (261)
Archives of Internal Medicine, 1979 From the clinician's standpoint, an ideal bronchodilator should have (1) selectivity for bronchial smooth muscle, (2) minimal stimulatory effects on the cardiovascular and central nervous system, (3) prolonged action, (4) rapid onset of action, and (5) oral effectiveness for patient convenience. In addition, bronchodilation should occur in both central
Wanner, Adam, Adam Wanner
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BMC Pulmonary MedicineBackground A positive bronchodilator response has been defined as a 12% increase in the forced expiratory volume in one second (FEV1) or forced vital capacity (FVC) from their respective pre-bronchodilator values, combined with at least a 0.2 L absolute ...
Afe Alexis +3 more
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Frontiers in Pharmacology, 2021 Background: Infants with severe bronchopulmonary dysplasia (BPD) are commonly treated with off-label drugs due to lack of approved therapies. To prioritize drugs for rigorous efficacy and safety testing, it is important to describe exposure patterns in ...
T. Lewis +5 more
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Pharmaceuticals, 2021 Cucumis sativus L. is globally cultivated as an edible vegetable. Besides its nutritional benefits, it is used in traditional medicines against various ailments. The current study was designed to elucidate the multi-target mechanisms of a C.
Muqeet Wahid +7 more
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Bronchodilator efficacy of extrafine glycopyrronium bromide: the Glyco 2 study
International Journal of COPD, 2017 Dave Singh,1 Mario Scuri,2 Sara Collarini,2 Stefano Vezzoli,2 Fabrizia Mariotti,2 Annamaria Muraro,2 Daniela Acerbi2 1Medicines Evaluation, University Of Manchester, University Hospital of South Manchester, Manchester, UK; 2Global Clinical Development ...
Singh D +6 more
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Managing bronchiolitis in pediatric patients: Current evidence
Indian Journal of Respiratory Care, 2022 Background: Acute bronchiolitis is an inflammatory process affecting small airways. Although most cases are self-limiting, it is still one of the most common causes of hospitalization below 24 months of age. Treatment is mainly supportive. The purpose of
Subhranshu Sekhar Dhal, Hiremath Sagar
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Bronchodilators for bronchiolitis [PDF]
Cochrane Database of Systematic Reviews, 2006 Bronchiolitis is an acute, viral lower respiratory tract infection affecting infants and often treated with bronchodilators.To assess the effects of bronchodilators on clinical outcomes in infants with acute bronchiolitis.We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, Issue 1) which contains the ...
Anne M, Gadomski, Melissa B, Scribani
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Pharmaceuticals, 2022 Apart from the nutritional value, Cucumis sativus L. has also been used in the traditional medicine of Iran, Pakistan, and India. Its seeds are used by herbalists to treat gastrointestinal, respiratory, and urinary problems.
Muqeet Wahid +5 more
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The future of bronchodilation: looking for new classes of bronchodilators [PDF]
European Respiratory Review, 2019 Available bronchodilators can satisfy many of the needs of patients suffering from airway disorders, but they often do not relieve symptoms and their long-term use raises safety concerns. Therefore, there is interest in developing new classes that could help to overcome the limits that characterise the existing classes.At least nine potential new ...
Cazzola, Mario +2 more
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Frontiers in Pharmacology, 2020 Local anesthetics (LAs), such as lidocaine and mexiletine, inhibit bronchoconstriction in asthmatics, but adverse effects limit their use for this specific clinical application.
Katharinne Ingrid Moraes Carvalho +10 more
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