The blue one takes a battering why do young adults with asthma overuse bronchodilator inhalers? A qualitative study [PDF]
, 2013 Objective: Overuse of short-acting bronchodilators is internationally recognised as a marker of poor asthma control, high healthcare use and increased risk of asthma death. Young adults with asthma commonly overuse short-acting bronchodilators. We sought
Cole, S, Griffiths, C, Seale, C
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Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts
Frontiers in Pharmacology, 2019 Background: Interleukin (IL)-26 is a neutrophil-mobilizing and bactericidal cytokine that is enhanced in human airways in vivo in response to endotoxin from Gram-negative bacteria.
Karlhans Fru Che +4 more
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The 24 hour lung function time profile of olodaterol once daily versus placebo and tiotropium in patients with moderate to very severe chronic obstructive pulmonary disease [PDF]
, 2014 Background: Olodaterol is a once-daily long-acting β2-agonist being investigated for the treatment of chronic obstructive pulmonary disease, with ≥ 24 hour bronchodilator activity.
Aumann, Joseph-Leon +5 more
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"Safety health impacts of particulate matter from excavation work sites" [PDF]
, 2012 Gli studi epidemiologici hanno evidenziato una relazione lineare tra il particolato aerodisperso e gli effetti sulla salute dell'uomo. E' dunque interessante comprendere quale sia realmente il rischio a cui va incontro la popolazione esposta ad ...
G. Pizzo, M. Clerico
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Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events (Review) [PDF]
, 2009 Background Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are ...
Cates, CJ, Jaeschke, R, Lasserson, TJ
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Something Is Changing in Viral Infant Bronchiolitis Approach
Frontiers in Pediatrics, 2022 Acute Viral Bronchiolitis is one of the leading causes of hospitalization in the first 12–24 months of life. International guidelines on the management of bronchiolitis broadly agree in recommending a minimal therapeutic approach, not recommending the ...
Paolo Bottau +7 more
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Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [PDF]
, 2015 Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with COPD, which measured baseline (pretreatment) blood eosinophil levels, to ...
Barnes, NC +6 more
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Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene. [PDF]
, 2014 BackgroundPreserved Ratio Impaired Spirometry (PRISm), defined as a reduced FEV1 in the setting of a preserved FEV1/FVC ratio, is highly prevalent and is associated with increased respiratory symptoms, systemic inflammation, and mortality.
Beaty, Terri H +14 more
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Allergology International, 2005 Background: Asthma can have a negative impact on the productivity of paid and unpaid individuals. In this study, we aimed to investigate the impact of salmeterol, which, in recent years, has become available for the treatment of asthma in Japan, on the ...
Takehiko Miyagawa, Shuzo Nishimura
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The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD : current evidence and future prospects [PDF]
, 2019 Long-acting bronchodilators are the cornerstone of pharmacologic treatment of chronic obstructive pulmonary disease (COPD). Spiolto (R) or Stiolto (R) is a fixed-dose combination (FDC) containing two long-acting bronchodilators, the long-acting ...
Brusselle, Guy, Derom, Eric, Joos, Guy
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