Electroanalytical overview: The electroanalytical detection of theophylline
Talanta Open, 2021 In this overview, we explore the electroanalytical determination of theophylline. Theophylline finds use as a bronchodilator for treating diseases such as asthma and chronic obstructive pulmonary disease (COPD).
Robert D Crapnell, Craig E Banks
exaly +3 more sources
The Effect of CYP1A2 Gene Polymorphisms on Caffeine Pharmacokinetics and Exercise Performance in Male Recreational Athletes. [PDF]
Eur J Sport SciABSTRACT This study examined the effects of caffeine consumption on endurance exercise performance, and the influence of CYP1A2 gene polymorphisms in caffeine pharmacokinetics and exercise performance. The data sets of two randomised, double blind, placebo‐controlled crossover study design experiments have been merged.
Masters C +4 more
europepmc +2 more sources
Molecular simulations and Markov state modeling reveal the structural diversity and dynamics of a theophylline-binding RNA aptamer in its unbound state. [PDF]
PLoS ONE, 2017 RNA aptamers are oligonucleotides that bind with high specificity and affinity to target ligands. In the absence of bound ligand, secondary structures of RNA aptamers are generally stable, but single-stranded and loop regions, including ligand binding ...
Becka M Warfield, Peter C Anderson
doaj +1 more source
PLoS ONE, 2021 BackgroundA synergism has been reported between theophylline and corticosteroids, wherein theophylline increases and restores the anti-inflammatory effect of inhaled corticosteroids (ICS) by enhancing histone deacetylase-2 (HDAC) activity.
Tiankui Shuai +6 more
doaj +1 more source
Electroconvulsive therapy in an older patient with recurrent major depressive disorder and a permanent pacemaker: A case report. [PDF]
PCN RepAbstract Background Electroconvulsive therapy (ECT) is highly effective for severe or treatment‐resistant major depressive disorder, including in older adults. In patients with permanent pacemakers, however, ECT may be avoided because of concern about device malfunction or arrhythmia.
Omori W +4 more
europepmc +2 more sources
The Impact of CYP1A2 and CYP2E1 Genes Polymorphism on Theophylline Response [PDF]
Journal of Clinical and Diagnostic Research, 2016 Theophylline is a medicine with narrow therapeutic index. This implies that a small change in dosage would cause side effects. Theophylline is metabolized by CYP1A2 and CYP2E1.
Em Sutrisna
doaj +1 more source
Isolation, characterization and application of theophylline-degrading Aspergillus fungi
Microbial Cell Factories, 2020 Background Caffeine, theobromine and theophylline are main purine alkaloid in tea. Theophylline is the downstream metabolite and it remains at a very low level in Camellia sinensis.
Binxing Zhou +6 more
doaj +1 more source
A Prospective Survey on Safety of Sustained-Release Theophylline in Treatment of Asthma and COPD
Allergology International, 2006 Background: Theophylline is a useful drug for the treatment of asthma. The Asthma Prevention and Management Guidelines (JGL) recommend use of sustained-release theophylline products as controllers and of injectable aminophylline products as relievers ...
Sohei Makino +7 more
doaj +1 more source
Prospective Survey on Safety Evaluation of Injectable Methylxanthines in Japan
Allergology International, 2006 Background: Injectable methylxanthines are useful drugs in the treatment of asthma. The Asthma Prevention and Management Guidelines (JGL) that are followed in Japan recommend the use of sustained-release theophylline to control the disease and use of ...
Ken Ohta +7 more
doaj +1 more source
Pharmaceuticals, 1998 Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2-agonists became more widely used.
openaire +5 more sources