Pharmacodynamic and pharmacokinetic effects of flumazenil and theophylline application in rats acutely intoxicated by diazepam [PDF]
Vojnosanitetski Pregled, 2009 Background/Aim. The majority of symptoms and signs of acute diazepam poisoning are the consequence of its sedative effect on the CNS affecting selectively polisynaptic routes by stimulating inhibitory action of GABA.
Šegrt Zoran +7 more
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Pharmaceuticals, 2010 Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2 ...
Peter J. Barnes
doaj +6 more sources
Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial. [PDF]
, 2015 BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with high morbidity, mortality, and health-care costs. An incomplete response to the anti-inflammatory effects of inhaled corticosteroids is present in COPD.
Alyn Morice +68 more
core +4 more sources
Rate-controlled rectal drug delivery in man with a hydrogel preparation [PDF]
, 1986 Cylindrical hydrogels of hydroxyethyl methacrylate (HEMA) and ethylene glycol dimethacrylate (EGDMA) as crosslinking agent were prepared by radical polymerization at 70°C.
Boer, A.G. de +4 more
core +3 more sources
Loss of PopZ At activity in Agrobacterium tumefaciens by Deletion or Depletion Leads to Multiple Growth Poles, Minicells, and Growth Defects. [PDF]
, 2017 Agrobacterium tumefaciens grows by addition of peptidoglycan (PG) at one pole of the bacterium. During the cell cycle, the cell needs to maintain two different developmental programs, one at the growth pole and another at the inert old pole.
Bonnie Bassler +4 more
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Real-time assessment of critical quality attributes of a continuous granulation process [PDF]
, 2013 There exists the intention to shift pharmaceutical manufacturing of solid dosage forms from traditional batch production towards continuous production. The currently applied conventional quality control systems, based on sampling and time-consuming off ...
Córdoba Díaz, Damián +6 more
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Severe theophylline poisoning treated with continuous venovenous hemodialysis in a child
The Turkish Journal of Pediatrics, 2016 Theophylline poisoning generally occurs due to acute high dose intake as well as chronic intake of the medication. Toxicity symptoms can be seen with a plasma concentration of theophylline over 20 μg/ml.
Ayhan Yaman +7 more
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Theophylline Enhances In Vitro Fertilization and Embryo Production in Buffaloes
Tropical Animal Science Journal, 2023 This study aimed to investigate the effect of theophylline on in vitro fertilization of buffalo oocytes and embryo development in subsequent in vitro embryo culture.
I. Akter +5 more
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Pulmonary outcomes following specialized respiratory management for acute cervical spinal cord injury: a retrospective analysis. [PDF]
, 2017 Study designRetrospective analysis.ObjectivesTo identify multivariate interactions of respiratory function that are sensitive to spinal cord injury level and pharmacological treatment to promote strategies that increase successful liberation from ...
Crew, JD +5 more
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Systematic Comparison and Rational Design of Theophylline Riboswitches for Effective Gene Repression
Microbiology Spectrum, 2023 Riboswitches are promising regulatory tools in synthetic biology. To date, 25 theophylline riboswitches have been developed for regulation of gene expression in bacteria. However, no one has systematically evaluated their regulatory effects.
Xun Wang +7 more
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