Results 201 to 210 of about 17,165 (261)
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International Journal of Pharmaceutics, 1996
Abstract Aerosols formed by three salts and the free base of albuterol were compared following their formation from similarly micronized crystalline powders held in a model dry powder inhaler (DPI) under varying environmental conditions. Aqueous solubility at 22°C was the greatest for albuterol adipate diethanolate (353 mg/ml), followed by albuterol ...
Peter R. Byron, Rajkumari N. Jashnani
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Abstract Aerosols formed by three salts and the free base of albuterol were compared following their formation from similarly micronized crystalline powders held in a model dry powder inhaler (DPI) under varying environmental conditions. Aqueous solubility at 22°C was the greatest for albuterol adipate diethanolate (353 mg/ml), followed by albuterol ...
Peter R. Byron, Rajkumari N. Jashnani
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(R)-Albuterol for Asthma: Pro [a.k.a. (S)-Albuterol for Asthma: Con]
American Journal of Respiratory and Critical Care Medicine, 2006Is there scientific evidence to support the replacement of the beta-agonist racemic albuterol with levalbuterol--that is, (R)-albuterol? The argument presented further refines the question as "Do we wish to continue to treat asthma with a mixture of albuterol, of which half is an agent with no known benefit--that is, (S)-albuterol--and which may ...
William J. Calhoun, Bill T. Ameredes
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Journal of pharmacy and practice, 2019
Objective: Nebulized heparin has been proposed to improve pulmonary function in patients with inhalation injuries. The purpose of this study was to evaluate the impact of nebulized heparin with N-acetylcysteine (NAC) and albuterol on the duration of ...
K. McGinn+4 more
semanticscholar +1 more source
Objective: Nebulized heparin has been proposed to improve pulmonary function in patients with inhalation injuries. The purpose of this study was to evaluate the impact of nebulized heparin with N-acetylcysteine (NAC) and albuterol on the duration of ...
K. McGinn+4 more
semanticscholar +1 more source
Prednisolone Plus Albuterol Versus Albuterol Alone in Mild to Moderate Bronchiolitis
Clinical Pediatrics, 2000To evaluate combination therapy of mild to moderate bronchiolitis with bronchiodilators and corticosteroids, we treated 51 young children with first-time wheezing and symptoms of respiratory tract infection with albuterol plus either prednisolone or placebo for 5 days. Disease severity was scored on days 0, 2, 3, and 6. On day 2, prednisolone resulted
Noorkarim Nagji+5 more
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Albuterol HFA is as effective as albuterol CFC in preventing exercise-induced bronchoconstriction
Annals of Allergy, Asthma & Immunology, 2002Secondary to the phase-out of chlorofluorocarbons (CFCs), the albuterol (Ventolin, GlaxoSmithKline, Uxbridge, Middlesex, United Kingdom) pressurized metered-dose inhaler (MDI) has been formulated in a non-ozone-depleting propellant, hydrofluoroalkane (HFA) 134a.To compare the efficacy of albuterol HFA to albuterol CFC and placebo HFA in protecting ...
Hawksworth, R J+4 more
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American Review of Respiratory Disease, 2015
The effect of pharmacologic agents on mast cell mediator release was investigated in vivo. Eight atopic asthmatic subjects with airways relatively unreactive to nonspecific stimuli (geometric mean PC20 methacholine, 4.0 mg/ml) underwent single ...
P. Howarth+5 more
semanticscholar +1 more source
The effect of pharmacologic agents on mast cell mediator release was investigated in vivo. Eight atopic asthmatic subjects with airways relatively unreactive to nonspecific stimuli (geometric mean PC20 methacholine, 4.0 mg/ml) underwent single ...
P. Howarth+5 more
semanticscholar +1 more source
The therapeutic ratio of R-albuterol is comparable with that of RS-albuterol in asthmatic patients
Journal of Allergy and Clinical Immunology, 2001It has been suggested that R-albuterol produces bronchodilation that is comparable with that of racemic albuterol (RS-albuterol) on a 4:1 dose-for-dose basis but systemic side effects on a 2:1 basis, implying better therapeutic ratio for R-albuterol.We sought to carefully compare the bronchodilating and systemic effects of R- and RS-albuterol by using ...
Mona Palmqvist+5 more
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Effects of a PICU Status Asthmaticus De-Escalation Pathway on Length of Stay and Albuterol Use*
Pediatric Critical Care Medicine, 2018Objectives: Evaluate the effects of an asthma de-escalation clinical pathway on selected outcomes for patients admitted to a PICU with status asthmaticus. Design: Time series quality improvement trial. Setting: PICU in a tertiary care children’s hospital.
S. Brennan+2 more
semanticscholar +1 more source
Albuterol Aerosol Versus Albuterol Rotacaps® in Exercise-Induced Bronchospasm in Children
Journal of Asthma, 1995The purpose of this study was to determine the safety and effectiveness of albuterol aerosol 180 micrograms and albuterol powder 200 micrograms in the prevention of exercise-induced bronchospasm in children. Forty-six patients aged 4-11 years with asthma and exercise-induced bronchospasm were enrolled in this randomized, double-blind, single-dose ...
Allen L. Bishop+4 more
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A Comparison of Ipratropium and Albuterol vs Albuterol Alone for the Treatment of Acute Asthma
Chest, 1996To evaluate the role of inhaled ipratropium bromide in acute asthma, a double-blind study of 384 emergency department patients compared the effect of the combination of ipratropium and albuterol with that of albuterol alone. Patients were randomized to receive nebulizer treatments with either 2.5 mg of albuterol or 2.5 mg of albuterol mixed with 0.5 mg
D Levey+7 more
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