Results 201 to 210 of about 22,425 (261)
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JAAPA, 2022
ABSTRACT Albuterol has been a cornerstone of asthma treatment for several decades, but evidence suggests that it may be overused at the expense of more efficacious treatment. Albuterol may not even be appropriate for sole first-line rescue medication in some patients.
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ABSTRACT Albuterol has been a cornerstone of asthma treatment for several decades, but evidence suggests that it may be overused at the expense of more efficacious treatment. Albuterol may not even be appropriate for sole first-line rescue medication in some patients.
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Current Allergy and Asthma Reports, 2009
Albuterol has been used for more than 40 years to treat acute asthma exacerbations as a racemic mixture of isomers: the active form, (R)-albuterol, or levalbuterol, and (S)-albuterol, classically considered inert. The single-isomer formulation, levalbuterol, has been synthesized recently and used therapeutically when the racemate is deemed less ...
Bill T, Ameredes, William J, Calhoun
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Albuterol has been used for more than 40 years to treat acute asthma exacerbations as a racemic mixture of isomers: the active form, (R)-albuterol, or levalbuterol, and (S)-albuterol, classically considered inert. The single-isomer formulation, levalbuterol, has been synthesized recently and used therapeutically when the racemate is deemed less ...
Bill T, Ameredes, William J, Calhoun
openaire +2 more sources
International Journal of Pharmaceutics, 1996
Abstract Aerosols formed by three salts and the free base of albuterol were compared following their formation from similarly micronized crystalline powders held in a model dry powder inhaler (DPI) under varying environmental conditions. Aqueous solubility at 22°C was the greatest for albuterol adipate diethanolate (353 mg/ml), followed by albuterol ...
Rajkumari N. Jashnani, Peter R. Byron
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Abstract Aerosols formed by three salts and the free base of albuterol were compared following their formation from similarly micronized crystalline powders held in a model dry powder inhaler (DPI) under varying environmental conditions. Aqueous solubility at 22°C was the greatest for albuterol adipate diethanolate (353 mg/ml), followed by albuterol ...
Rajkumari N. Jashnani, Peter R. Byron
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Multiple‐Dose Albuterol Kinetics
The Journal of Clinical Pharmacology, 1986Albuterol a beta‐adrenergic agonist bronchodilator, was studied in 12 healthy male volunteers to evaluate the steady‐state pharmacokinetics following oral administration of 4‐mg tablets, given every six hours for five days. The kinetics of albuterol were best described by a two‐compartment open model with first‐order absorption kinetics.
M L, Powell +6 more
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Prednisolone Plus Albuterol Versus Albuterol Alone in Mild to Moderate Bronchiolitis
Clinical Pediatrics, 2000To evaluate combination therapy of mild to moderate bronchiolitis with bronchiodilators and corticosteroids, we treated 51 young children with first-time wheezing and symptoms of respiratory tract infection with albuterol plus either prednisolone or placebo for 5 days. Disease severity was scored on days 0, 2, 3, and 6. On day 2, prednisolone resulted
J, Goebel +5 more
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(R)-Albuterol for Asthma: Pro [a.k.a. (S)-Albuterol for Asthma: Con]
American Journal of Respiratory and Critical Care Medicine, 2006Is there scientific evidence to support the replacement of the beta-agonist racemic albuterol with levalbuterol--that is, (R)-albuterol? The argument presented further refines the question as "Do we wish to continue to treat asthma with a mixture of albuterol, of which half is an agent with no known benefit--that is, (S)-albuterol--and which may ...
Bill T, Ameredes, William J, Calhoun
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Albuterol Aerosol Versus Albuterol Rotacaps® in Exercise-Induced Bronchospasm in Children
Journal of Asthma, 1995The purpose of this study was to determine the safety and effectiveness of albuterol aerosol 180 micrograms and albuterol powder 200 micrograms in the prevention of exercise-induced bronchospasm in children. Forty-six patients aged 4-11 years with asthma and exercise-induced bronchospasm were enrolled in this randomized, double-blind, single-dose ...
E A, Bronsky +4 more
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