Trisomy 5p: Long Recognized, Rarely Published‐ Three New Cases and Review of the Literature
ABSTRACT Complete trisomy 5p is a rare chromosomal disorder caused by a duplication of the short arm of chromosome 5. Current data suggest that complete trisomy 5p presents as a distinct clinical syndrome including but not limited to seizures, developmental delays, facial dysmorphisms, failure to thrive, and recurrent respiratory infections.
Gabriela J. Kim +2 more
wiley +1 more source
Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma [PDF]
In acute asthma inhaled beta 2-agonists are often administered to relieve bronchospasm by wet nebulisation, but some have argued that metered-dose inhalers with a holding chamber (spacer) can be equally effective.
Ba +63 more
core +1 more source
BRASH Syndrome: A Vicious Yet Reversible Cause of AV Nodal Blockade
ABSTRACT Early recognition of BRASH syndrome is crucial, as the synergistic interplay of AV nodal blockade, renal failure, and hyperkalemia can rapidly lead to circulatory collapse. Prompt identification and withdrawal of offending agents enable complete recovery from this reversible condition.
Anuj Subedi +5 more
wiley +1 more source
Safety and Efficacy of Very Low‐Dose Multi‐Nut Oral Immunotherapy in Children
ABSTRACT Background Oral immunotherapy (OIT) is a management strategy for food allergies, typically one at a time, with maintenance doses ≥ 300 mg protein. However, 30% of allergic children have multiple trigger foods, and large maintenance doses are associated with side effects. If efficacious, Very Low‐Dose OIT (VLOIT) may enhance safety in multi‐OIT.
Julia E. M. Upton +17 more
wiley +1 more source
Comparison of albuterol sulphate and base dry powder particulate deposition using the Calu-3 lung epithelial model [PDF]
To effectively predict the fate of formulated inhalation compounds delivered to the lung, a model of the airway epithelium should reflect drug permeability and transport characteristics in vivo.
Bebawy, M, Haghi, M, Traini, D, Young, P
core
Trends in Medication Use Among Young Adults and the Covid‐19 Pandemic Effect
ABSTRACT Introduction The COVID‐19 pandemic caused unprecedented disruptions in healthcare delivery, and changes in medication utilization patterns. While previous studies examined specific therapeutic classes or populations, there is limited longitudinal evidence on medication trends among young adults throughout and beyond the pandemic.
Meital Zur +3 more
wiley +1 more source
Cardiovascular changes after administration of aerosolized salbutamol in horses: five cases [PDF]
Prevention and treatment of intraoperative hypoxemia in horses is difficult and both efficacy and safety of therapeutic maneuvers have to be taken into account.
AE Wagner +24 more
core +5 more sources
SAFETY OF AS-NEEDED ALBUTEROL-BUDESONIDE BY BACKGROUND INHALED CORTICOSTEROID MAINTENANCE DOSE IN ADULTS WITH MODERATE-TO-SEVERE ASTHMA [PDF]
Bradley E. Chipps +7 more
openalex +1 more source
Efficacy and Safety of Pediatric Critical Care Physician Telemedicine Involvement in Rapid Response Team and Code Response in a Satellite Facility [PDF]
OBJECTIVES: Satellite inpatient facilities of larger children's hospitals often do not have on-site intensivist support. In-house rapid response teams and code teams may be difficult to operationalize in such facilities.
Berrens, Zachary J. +3 more
core +2 more sources
Children in Aotearoa New Zealand experience variable asthma care. This review reveals critical gaps in education, treatment adherence, and culturally safe services, disproportionately affecting Māori and Pacific children. Strengthening family/whānau‐centred and culturally responsive care is vital for improving outcomes.
J. Blamires +2 more
wiley +1 more source

