Results 71 to 80 of about 26,208 (306)

Adjunctive Pharmacotherapies in Children With Asthma Exacerbations Requiring Continuous Albuterol Therapy: Findings From The Ohio Pediatric Asthma Repository.

Hospital Pediatrics, 2018
OBJECTIVES To identify associations between use of ipratropium and/or intravenous magnesium and outcomes of children hospitalized with acute asthma exacerbations and treated with continuous albuterol.
S. Shein, Obada Farhan, N. Morris, Nabihah Mahmood, S. Alter, J. B. Biagini Myers, Samantha M Gunkelman, C. Kercsmar, G. K. Khurana Hershey, Lisa J. Martin, K. McCoy, J. Ruddy, K. Ross   +12 more
semanticscholar   +1 more source

Dupilumab Efficacy and Safety in Patients With Persistent Asthma: Asia–Pacific Region

Clinical &Experimental Allergy, EarlyView.
Asthma prevalence is increasing in the Asia–Pacific region, and this population is frequently underrepresented in phase 3 clinical studies. We demonstrate Dupilumab's efficacy and safety among patients with uncontrolled moderate‐to‐severe type 2 asthma.
Qingling Zhang, Nanshan Zhong, Sahajal Dhooria, Xiuhua Fu, Haohui Fang, Jie Lin, Shuyang Zhu, Elizabeth Laws, Yi Wang, Vivian Li, Chih‐Chi Hu, Jennifer Maloney, Raolat M. Abdulai, Lacey B. Robinson   +13 more
wiley   +1 more source

Long-acting beta(2)-agonist in addition to tiotropium versus either tiotropium or long-acting beta(2)-agonist alone for chronic obstructive pulmonary disease [PDF]

, 2012
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropium are commonly used for managing persistent symptoms of chronic obstructive pulmonary disease.
Aaron, Aaron, Appleton, Arievich, Barr, Bateman, Berger, Brusasco, Calverley, Cazzola, Cheyne, Effing, Fujimoto, Gross, Hacken, Higgins, Hutchinson, Johnson, Kaplan, Karner, Lacasse, Mahler, Mahler, Marco, Meer, Meyer, Najafzadeh, Najafzadeh, New, Noord, Noord, Noord, Proskocil, Rodrigo, Roisman, Singh, Tanaka, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Vogelmeier, Vogelmeier, Wallukat, Welsh   +47 more
core   +1 more source

Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity‐matched cohort study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This large‐scale, propensity‐matched retrospective cohort study provides evidence that dupilumab treatment during pregnancy is not associated with an elevated risk of maternal adverse pregnancy outcomes (APOs). By utilizing real‐world data, it contributes critical insights into dupilumab's safety profile in pregnant women, addressing a crucial gap in ...
Sophie L. Preuß, Katja Bieber, Artem Vorobyev, Andreas Recke, Eva Lotta Moderegger, Henner Zirpel, Evelyn Gaffal, Diamant Thaçi, Khalaf Kridin, Ralf J. Ludwig   +9 more
wiley   +1 more source

Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and β\u3csub\u3e2\u3c/sub\u3e-agonist use [PDF]

, 2006
Background Vasodilator-stimulated phosphoprotein (VASP) mediates focal adhesion, actin filament binding and polymerization in a variety of cells, thereby inhibiting cell movement.
Batra, Vikas, Cirelli, Rosemary, Foster, Gayle C., Hastie, Annette T., Hawkins, Gregory A., Peters, Stephen P., Rybinski, Katherine A., Wu, Min, Zangrilli, James G.   +8 more
core   +1 more source

Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. [PDF]

, 2015
Medication adherence among patients with chronic diseases, such as COPD, may be suboptimal, and many factors contribute to this poor adherence. One major factor is the frequency of medication dosing.
Albertson, Timothy E, Harper, Richart, Murin, Susan, Sandrock, Christian   +3 more
core   +1 more source

Medication Utilization Among Children With Sickle Cell Disease in the United States

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background and Objective The medication management of children with sickle cell disease (SCD), especially since the release of the 2014 National Heart, Lung, and Blood Institute (NHLBI) SCD treatment guidelines, is not well described in the published literature.
Abiodun John Ologunowa, Kelly L. Matson, Jung Eun Lee, Meghan McCormick, Mary L. Greaney, Aisling R. Caffrey   +5 more
wiley   +1 more source

Effect of Nebulized Albuterol on Serum Lactate and Potassium in Healthy Subjects.

Academic Emergency Medicine, 2016
OBJECTIVES The objectives were to determine if nebulized albuterol causes an increase in the serum lactate level compared to placebo and, secondarily, to confirm that albuterol decreases serum potassium levels compared to placebo in patients with ...
T. Zitek, N. Cleveland, A. Rahbar, Joshua Parker, Chee Lim, Steven Elsbecker, W. Forred, D. Slattery   +7 more
semanticscholar   +1 more source

Uncovering New Therapeutic Targets for Amyotrophic Lateral Sclerosis and Neurological Diseases Using Real‐World Data

Clinical Pharmacology &Therapeutics, Volume 118, Issue 1, Page 242-251, July 2025.
Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost, Jeremy Y. Huang, Georgia Dermentzaki, Anna S. Blazier, Giorgio Gaglia, Timothy R. Hammond, Francesca Frau, Mary Clare McCorry, Dimitry Ofengeim, Jennifer L. Wilson   +9 more
wiley   +1 more source

The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis

Interdisciplinary Perspectives on Infectious Diseases, 2012
Objective. To evaluate the effects of albuterol use in young infants admitted with respiratory syncytial virus (RSV) bronchiolitis with regards to length of time on supplemental oxygen and length of stay (LOS).
Michael T. Del Vecchio, Laura E. Doerr, John P. Gaughan   +2 more
doaj   +1 more source