Results 81 to 90 of about 22,425 (261)

The crucial role of leucine concentration on spray dried mannitol-leucine as a single carrier to enhance the aerosolization performance of Albuterol sulfate [PDF]

open access: yes, 2018
Generally, DPI formulations show low fine particle fraction (FPF) due to poor detachment of drug particles from carrier during inhalation. L-Leucine, with varying concentrations (ranging from 0 to 10% w/w), were introduced into a 60%w/v mannitol solution
Adia   +42 more
core   +2 more sources

Normal Immune Function in a Newborn With Early Identification of a SAMD9 Mutation Presenting With Growth Restriction, Thrombocytopenia, and Primary Adrenal Insufficiency

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
A de novo SAMD9 variant G1048R is associated with MIRAGE syndrome symptoms in a neonate. SAMD9 G1048R's predicted tertiary structure has similarity to known MIRAGE variants. SAMD9 expression is increased in pediatric viral infection. Neonatal MIRAGE may lack immune deficiency and myelodysplastic syndrome.
Kevin MingJie Gao   +7 more
wiley   +1 more source

Intentional salbutamol poisoning: report of two siblings and review of the literature

open access: yesSaudi Journal of Emergency Medicine
Background: About 65% of poisoning cases are related to children and of these, more than half of the patients are 5-year-old or less. While non-accidental poisoning is rare.
Dana Altamimi   +2 more
doaj   +1 more source

A Simple and Scalable Synthesis of N‐Nitroso Salbutamol Impurities A, D, and F

open access: yesJournal of Heterocyclic Chemistry, Volume 62, Issue 11, Page 1752-1756, November 2025.
ABSTRACT To ensure strict quality control standards, improve yields, and meet regulatory requirements, the synthesis of N‐nitroso impurities of salbutamol is essential. These studies help in understanding, monitoring, and mitigating the risks associated with the presence of potentially harmful nitrosamine impurities in pharmaceuticals.
Kottolla Sai Prasad   +2 more
wiley   +1 more source

Section 2. Exercise-Induced Bronchospasm: Albuterol versus Montelukast

open access: yesWorld Allergy Organization Journal, 2010
Exercise-induced bronchospasm (EIB) involves airway obstruction with an onset shortly after exercising. It can occur in individuals without a diagnosis of asthma, but is most common in asthmatic patients (and in this scenario may be referred to as ...
Gene Colice, MD, FCCP   +1 more
doaj   +1 more source

Pediatric asthma severity score is associated with critical care interventions [PDF]

open access: yes, 2017
AIM: To determine if a standardized asthma severity scoring system (PASS) was associated with the time spent on continuous albuterol and length of stay in the pediatric intensive care unit (PICU).
Krupp, Nadia   +2 more
core   +2 more sources

Assessment of Central Airways Mechanics Using Dynamic Magnetic Resonance Imaging (Cine‐MRI): A Comparison to Flexible Bronchoscopy

open access: yesPediatric Pulmonology, Volume 60, Issue 11, November 2025.
ABSTRACT Background Flexible bronchoscopy (FOB) is the current gold standard for diagnosing tracheobronchomalacia (TBM). While dynamic magnetic resonance imaging (cine‐MRI) has emerged as a radiation‐free alternative for TBM diagnosis, a direct comparison of its diagnostic performance with FOB has not yet been performed.
Giulia Roberto   +6 more
wiley   +1 more source

Evaluation of aerosolized medications during parabolic flight maneuvers [PDF]

open access: yes
The goal was to visually evaluate the effect gravity has on delivery of medications by the use of various aerosol devices. During parabolic flight the same four aerosols were retested as performed in studio ground tests.
Gosbee, John   +2 more
core   +1 more source

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