Results 41 to 50 of about 91,956 (289)

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study

Hepatology, EarlyView., 2022
Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef, Milan J. Sonneveld, Maryam Kavousi, M. Arfan Ikram, Robert A. de Man, Robert J. de Knegt   +5 more
wiley   +1 more source

Average alcohol consumption among patients diagnosed with liver cirrhosis: A cross-sectional analysis [PDF]

Pharmacia
Background: Alcohol-related liver cirrhosis is a leading cause of chronic liver disease worldwide. Risk and progression are dose-dependent and influenced by exposure duration and sex-specific susceptibility.
Kamen Valentinov Danov, Dariya Lyubomirova Todorova, Diyan Kirilov Genov, Maria Sevdelinova Chaneva, Angelina Georgieva Kirkova-Bogdanova, Maria Stamova Vakrilova Becheva, Maria Georgieva Moneva-Sakelarieva, Yozlem Ali Kobakova, Ventseslava Petrova Atanasova, Radoslav Fedeev Todorov, Nikolay Zarkov Bashev, Ismail Elhanov Bashov, Yonko Tsvetanov Yonchev, Vasil Sotirov Kyosev, Kiril Todorov Atliev, Niya Emilova Semerdzhieva, Petar Yordanov Atanasov, Danka Petrova Obreshkova, Stefka Achkova Ivanova   +18 more
doaj   +3 more sources

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Targeted decrease of portal hepatic pressure gradient improves ascites control after TIPS

Hepatology, EarlyView., 2022
The river diagram demonstrates that after transjugular intrahepatic portosystemic shunt insertion (TIPS) the majority of patients without ascites and 50% of the patients with ascites detectable at ultrasound, show the best response in the long term follow‐up.
Alexander Queck, Louise Schwierz, Wenyi Gu, Philip G. Ferstl, Christian Jansen, Frank E. Uschner, Michael Praktiknjo, Johannes Chang, Maximilian J. Brol, Filippo Schepis, Manuela Merli, Christian P. Strassburg, Jennifer Lehmann, Carsten Meyer, Jonel Trebicka   +14 more
wiley   +1 more source

Risk of hepatocellular carcinoma in Danish outpatients with alcohol-related cirrhosis [PDF]

Journal of Hepatology, 2020
Accurate estimates of hepatocellular carcinoma (HCC) risk in patients with cirrhosis are important to guide surveillance strategies. We described HCC risk among outpatients with alcohol-related cirrhosis and contrasted the risk of death from HCC with the risk of death from variceal bleeding or trauma.This was a nationwide, registry-based historical ...
Peter Jepsen, Frederik Kraglund, Joe West, Gerda E. Villadsen, Henrik Toft Sørensen, Hendrik Vilstrup   +5 more
openaire   +2 more sources

Are there gender differences in the geography of alcohol-related mortality in Scotland? An ecological study [PDF]

, 2009
<b>Background</b> There is growing concern about alcohol-related harm, particularly within Scotland which has some of the highest rates of alcohol-related death in western Europe.
Mitchell Richard, Mitchell, Ri., Emslie, Carol; id_orcid, Emslie Carol, Mitchell, Richard, Richard Mitchell, Emslie, C., Carol Emslie   +7 more
core   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Post-treatment stage of change predicts 12-month outcome of treatment for alcohol problems. [PDF]

, 2013
AIMS: To evaluate relationships between clients' self-reported 'stage of change' and outcomes after treatment for alcohol problems. METHODS: Using data from the 'United Kingdom Alcohol Treatment Trial', clients who had received at least one session of ...
UKATT Research Team, McCambridge, Jim, Heather, Nick   +2 more
core   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Aflatoxin exposure and viral hepatitis in the etiology of liver cirrhosis in the Gambia, West Africa. [PDF]

, 2008
BACKGROUND: Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been conducted in this region.
James J. Goedert, Akano, Aliu O, Kirk, Gregory D, Mendy, Maimuna, Sam, Omar, Mark H. Kuniholm, Gregory D. Kirk, Ebrima Bah, Maimuna Mendy, Hainaut, Pierre, Pierre Hainaut, Omar Sam, Bah, Ebrima, Hall, Andrew J, Lesi, Olufunmilayo A, Hilton Whittle, Kuniholm, Mark H, Olufunmilayo A. Lesi, Whittle, Hilton, Andrew J. Hall, Goedert, James J, Aliu O. Akano   +21 more
core   +1 more source