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Gut Microbiota and Ageing: A Critical Crosstalk in Alcohol-Related Liver Disease [PDF]

Microorganisms
Alcohol-related liver disease (ALD) poses a significant global health burden, driven by complex mechanisms including oxidative stress, inflammation, and gut–liver axis disruption.
Yupin Tan, Yirui Hu, Zhuang Cao, Xinyang Wang, Yonggang Yuan, Huikuan Chu   +5 more
doaj   +2 more sources

Metabolic Reprogramming Driven by Modifiable Lifestyle Factors in Metabolic Syndrome and Alcohol-Related Liver Disease: A Narrative Review [PDF]

Metabolites
Background: Metabolic syndrome (MetS) and alcohol-related liver disease (ALD) are increasingly recognized as interconnected disorders linked by shared mechanisms of lifestyle-driven metabolic reprogramming.
Daniela Mihăilă, Horațiu-Paul Domnariu, Doru-Florian-Cornel Moga, Carmen-Daniela Domnariu   +3 more
doaj   +2 more sources

Cigarette smoking and alcohol-related liver disease [PDF]

Liver Research
China is a major consumer of alcohol and tobacco. Tobacco and alcohol use are closely linked, with up to 90% of alcoholics having a history of tobacco use, and heavy smokers also tending to be alcoholics.
Hui-Min Lin, Jing-Rong Zhang, Meng-Xue Li, Hui Hou, Hua Wang, Yan Huang   +5 more
doaj   +2 more sources

Propensity Score Matching Analysis for Alcohol‐Related Liver Disease [PDF]

Health Science Reports
Objectives This study aims to investigate the impact of comorbidity with chronic hepatitis B (CHB) on the survival rates and incidence of liver cancer in patients with alcohol‐related liver disease (ARLD).
Fangfang Duan, Shanshan Song, Hang Zhai, Yazhi Wang, Jun Cheng, Song Yang   +5 more
doaj   +2 more sources

Alcohol-related liver disease and liver transplantation [PDF]

Kosin Medical Journal, 2022
Alcohol-related liver disease (ALD) has become the major cause of liver transplantation (LT) in Korea, and is currently the most common cause of LT in Europe and the United States.
Musheer Shafqat, Ji Hoon Jo, Hyung Hwan Moon, Young Il Choi, Dong Hoon Shin   +4 more
doaj   +1 more source

Liver-lung axes in alcohol-related liver disease [PDF]

Clinical and Molecular Hepatology, 2020
Alcohol-related liver disease (ALD) and alcohol-related susceptibility to acute lung injury are the leading causes of morbidity and mortality due to chronic alcohol abuse.
Gavin E. Arteel
doaj   +1 more source

Lipidomics for the Prediction of Progressive Liver Disease in Patients with Alcohol Use Disorder

Metabolites, 2022
Alcohol-related liver disease is a public health care burden globally. Only 10–20% of patients with alcohol use disorder have progressive liver disease.
Bei Gao, Suling Zeng, Luca Maccioni, Xiaochun Shi, Aaron Armando, Oswald Quehenberger, Xinlian Zhang, Peter Stärkel, Bernd Schnabl   +8 more
doaj   +1 more source

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JHEP Reports, 2021
Summary: Alcohol-related liver disease characterises a broad spectrum of hepatic diseases that result from heavy alcohol use, and include alcohol-related steatosis, steatohepatitis, fibrosis, cirrhosis, and alcoholic hepatitis.
Bradley Fairfield, Bernd Schnabl
doaj   +1 more source

Targeting ferroptosis, a novel programmed cell death, for the potential of alcohol-related liver disease therapy

Frontiers in Pharmacology, 2023
Ferroptosis is a new iron-dependent cell death mode, which is different from the other types of programmed cell death, such as apoptosis, necrosis, and autophagy.
Jing-Fen Shi, Jing-Fen Shi, Yu’e Liu, Yan Wang, Ru Gao, Yi Wang, Jun Liu, Jun Liu   +7 more
doaj   +1 more source

Immune cells in alcohol-related liver disease

Liver Research, 2022
Alcohol-related liver disease (ALD), which is caused by excessive alcohol consumption, is one of the most common types of liver disease and a primary cause of hepatic injury, with a disease spectrum that includes steatosis, steatohepatitis, fibrosis ...
Honghai Xu, Hua Wang
doaj   +1 more source