Results 1 to 10 of about 2,535,651 (215)

Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B

Canadian Journal of Gastroenterology and Hepatology, 2022
Objectives. We assessed the potential of glial cell line-derived neurotrophic factor (GDNF) as a useful biomarker to predict cirrhosis in chronic hepatitis B (CHB) patients. Methods.
Guangyue Yang, Liping Zhuang, Tiantian Sun, Yee Hui Yeo, Le Tao, Wei Zhang, Wenting Ma, Liu Wu, Zongguo Yang, Yanqin Yang, Dongying Xue, Jie Zhang, Rilu Feng, Ebert Matthias P., Steven Dooley, Ekihiro Seki, Ping Liu, Cheng Liu   +17 more
doaj   +1 more source

Extracellular Vesicle-Encapsulated MicroRNA-375 from Bone Marrow-Derived Mesenchymal Stem Cells Inhibits Hepatocellular Carcinoma Progression through Regulating HOXB3-Mediated Wnt/β-Catenin Pathway

Analytical Cellular Pathology, 2022
Nowadays, microRNA-375 (miR-375) has been implicated in many types of cancers, including hepatocellular carcinoma (HCC), and the functions of miRNAs encapsulated by extracellular vesicles (EV) in HCC progression have also been extensively investigated ...
Zhaoxia Yu, Ju Liu, Qiqi Fan, Jun Yu, Xiaoting Ren, Xiaobin Wang   +5 more
doaj   +1 more source

Identification of immune-related target and prognostic biomarkers in PBMC of hepatocellular carcinoma

BMC Gastroenterology, 2023
Background  Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, and is characterized by insidious onset, rapid progression, and poor prognosis. Immunotherapy is a first-line treatment for advanced HCC.
Rui Hu, Wei Zhang, Zhiyi Han, Mengqing Ma, Qi Huang, Minling Lv, Wenfeng Ma, Xinfeng Sun, Wenxing Feng, Jing Li, Xin Zhong, Jialing Sun, Wei Yao, Xiaozhou Zhou   +13 more
doaj   +1 more source

Effect of Transcatheter Arterial Chemoembolization Combined with Radiofrequency Ablation on Liver Function and Immune Function in Patients with Hepatocellular Carcinoma

Emergency Medicine International, 2022
Objectives. To investigate the effects of transcatheter arterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) on liver function and immune function in patients with hepatocellular carcinoma (HCC). Methods.
Yan Zhou, Ying Qian, Weiming Xiong, Naijun Yan, Bing Hu, Zhiyuan Xiong, Weixin He   +6 more
doaj   +1 more source

FAT4 expression in peripheral blood mononuclear cells is associated with prognosis and immune cell infiltration in hepatocellular carcinoma

Scientific Reports, 2023
Peripheral blood mononuclear cell (PBMC) genes reflect the host immune status and could be suitable for evaluating the prognosis of patients with hepatocellular carcinoma (HCC), for which a reliable biomarker is unavailable and the host immune responses ...
Jing Li, Minling Lv, Qi Huang, Rui Hu, Xin Zhong, Xinfeng Sun, Wenxing Feng, Zhiyi Han, MengQing Ma, Wei Zhang, Xiaozhou Zhou   +10 more
doaj   +1 more source

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis [PDF]

, 2020
Background A non-invasive method to grade the severity of steatohepatitis and liver fibrosis is magnetic resonance imaging (MRI) based corrected T1 (cT1).
Banerjee, R, Banerjee, R, Bell, J.D., Bell, J.D., Hemingway, H., Hemingway, H., Hingorani, A.D., Hingorani, A.D., Kelly, M., Kelly, M., McGonigle, J., McGonigle, J., Neubauer, S., Neubauer, S., Nicholls, R.C., Nicholls, R.C., Parisinos, C.A., Parisinos, C.A., Patel, R.S., Patel, R.S., Thomas, E.L., Thomas, E.L., Wilman, H., Wilman, H., Yaghootkar, H., Yaghootkar, H.   +25 more
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Prognostic potential and mechanism of SORT1 and its co‐expressed genes in hepatocellular carcinoma based on integrative analysis of multiple database

Precision Medical Sciences, 2022
Abnormal SORT1 expression has been reported in various cancers. However, the expression and function of SORT1 in hepatocellular carcinoma (HCC) remain to be explored.
Minjie Lin, Mengying Zhu, Tingqiu Ge, Naiying Lu, Xiling Fu, Jiabao Chang   +5 more
doaj   +1 more source

Liver involvement in pediatric celiac disease [PDF]

, 2015
Celiac disease (CD) is an intestinal inflammatory disease that manifests in genetically susceptible individuals when exposed to dietary gluten. It is a common chronic disorder, with a prevalence of 1% in Europe and North America.
Anania, Caterina, Chiesa, Claudio, De Castro, Giovanna, De Luca, Ester, Pacifico, Lucia   +4 more
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Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood. [PDF]

, 2016
Excess collagen synthesis (fibrogenesis) in the liver plays a causal role in the progression of nonalcoholic fatty liver disease (NAFLD). Methods are needed to identify patients with more rapidly progressing disease and to demonstrate early response to ...
Angel, Thomas E, Beysen, Carine, Brenner, David A, Colangelo, Marc, Cui, Jeffrey, Decaris, Martin L, Emson, Claire L, Gatmaitan, Michelle, Hellerstein, Marc K, Hernandez, Carolyn, Lazaro, Len, Li, Kelvin W, Liu, Shanshan, Loomba, Rohit, Nyangau, Edna, Turner, Scott M, Wang, Yenny   +16 more
core   +1 more source

Patients’ preferences for nutrition-related health outcomes in liver disease : a preliminary study using an electronic questionnaire [PDF]

, 2014
Background: Patients with liver disease frequently have nutritional problems but intervening to improve these is challenging. Healthcare interventions that respond to patients’ needs are associated with better health outcomes but no studies investigating
Adams, Alberino, Anderson, Argyrous, Ashurst I de, Bradley, Carbone, Cook, Corner, Couper, Cullen, Department of Health., Department of Health., Department of Health., Devlin, Duncan, Galdas, Giguère, Hancock, Haywood, Hogg, Jackson, Jahagirdar, Johnson, Kibble, Koretz, Lacey, Mathers, Merli, Nicklin, Nicolucci, Pollard, Pope, Pulman, Richie, UK Government., Wong, Worth, Wright, Zimmermann, Zoellner   +40 more
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