Elevated endotoxin levels in non-alcoholic fatty liver disease [PDF]
Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty ...
Ashour, E. +70 more
core +1 more source
Regulating Intestinal Microbiota in the Prevention and Treatment of Alcohol-Related Liver Disease
When alcohol-related liver disease occurs, the number and composition ratio of intestinal microorganisms will accordingly change. The alcohol-induced changes in the intestinal microbiota play a pivotal role in the process of developing the alcohol ...
Xin Chi +5 more
doaj +1 more source
Integrated Care of Alcohol-Related Liver Disease [PDF]
Alcohol-related liver disease (ALD) is the medical manifestation of alcohol use disorder, a prevalent psychiatric condition. Acute and chronic manifestations of ALD have risen in recent years especially in young people and ALD is now a leading indication of liver transplantation (LT) worldwide. Such alarming trends raise urgent and unanswered questions
Gerald S. Winder +2 more
openaire +2 more sources
Background & Aims: In experimental models, alcohol induces acute changes in lipid metabolism that cause hepatocyte lipoapoptosis and inflammation. Here we study human hepatic lipid turnover during controlled alcohol intoxication.
Mads Israelsen +10 more
doaj +1 more source
Gut microbiota in alcohol-related liver disease: pathophysiology and gut-brain cross talk
Alcohol-related liver disease (ALD) from excessive alcohol intake has a unique gut microbiota profile. The disease progression-free survival in ALD patients has been associated with the degree of gut dysbiosis.
Lin Zhu +5 more
doaj +1 more source
Mortality in England and Wales attributable to current alcohol consumption. [PDF]
STUDY OBJECTIVE: To estimate the number of deaths attributable to current alcohol consumption levels in England and Wales by age and sex. DESIGN: Epidemiological approach using published relative risks and population data.
Britton, A, McPherson, K
core +1 more source
Epidemiology of Alcohol-associated Liver Disease
Alcohol-associated liver disease (ALD) is a consequence of excessive alcohol use. It comprises a spectrum of histopathologic changes ranging from simple steatosis, steatohepatitis, and cirrhosis to hepatocellular carcinoma.
Han, Sen +5 more
core +1 more source
Alcohol and premature death in Estonian men: a study of forensic autopsies using novel biomarkers and proxy informants. [PDF]
BACKGROUND: Alcohol makes an important contribution to premature mortality in many countries in Eastern Europe, including Estonia. However, the full extent of its impact, and the mechanisms underlying it, are challenging issues to research.
Tõnisson, Mailis +26 more
core +1 more source
Cystic fibrosis related chronic liver disease: a study of its influence upon prognosis and possible mechanisms for this; with specific reference to pulmonary and systemic haemodynamics [PDF]
MDTo assess the influence of chronic liver disease on survival a time dependent multivariate Cox regression analysis was It performed. The results confirmed that patients with evidence of chronic liver disease have a worse prognosis.
Williams, Simon Graham John
core +4 more sources
Epidemiology of Alcoholic Liver Disease in Korea
The harmful use of alcohol is associated with significant medical and socioeconomic burdens responsible for approximately 6% of all deaths worldwide. In Korea, the total alcohol consumption recently decreased slightly from 14.8 L of alcohol per person on
Sung Won Lee
doaj +1 more source

