Results 31 to 40 of about 435,985 (290)

Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication⋆

JHEP Reports, 2021
Background & Aims: In experimental models, alcohol induces acute changes in lipid metabolism that cause hepatocyte lipoapoptosis and inflammation. Here we study human hepatic lipid turnover during controlled alcohol intoxication.
Mads Israelsen, Min Kim, Tommi Suvitaival, Bjørn Stæhr Madsen, Camilla Dalby Hansen, Nikolaj Torp, Kajetan Trost, Maja Thiele, Torben Hansen, Cristina Legido-Quigley, Aleksander Krag   +10 more
doaj   +1 more source

Alcoholic hepatitis [PDF]

, 2018
Alcoholic hepatitis (AH) is a clinical manifestation on the spectrum of alcoholic liver diseases related to alcohol consumption. The mildest of these diseases is fatty liver, which can progress to AH and then lead to cirrhosis with continual alcohol use.
Naqvi, Syed, Padkins, Mitchell
core   +1 more source

Alcohol-related Liver Disease and sepsis.

European review for medical and pharmacological sciences, 2021
Sepsis is one of the most common complications and causes of death in patients with Alcohol-related Liver Disease. This narrative review will focus on several aspects of sepsis in the context of Alcohol-related Liver Disease. The pathophysiology of the increased susceptibility to infections consists mainly of impaired innate and adaptive immunity ...
Vassallo GA, Dionisi T, Tarli C, Augello G, Mirijello A, De Cosmo S, Gasbarrini A, Addolorato G   +7 more
openaire   +2 more sources

Regulating Intestinal Microbiota in the Prevention and Treatment of Alcohol-Related Liver Disease

Canadian Journal of Gastroenterology and Hepatology, 2020
When alcohol-related liver disease occurs, the number and composition ratio of intestinal microorganisms will accordingly change. The alcohol-induced changes in the intestinal microbiota play a pivotal role in the process of developing the alcohol ...
Xin Chi, Calvin Q. Pan, Shunai Liu, Danying Cheng, Ziwen Cao, Huichun Xing   +5 more
doaj   +1 more source

Gut microbiota in alcohol-related liver disease: pathophysiology and gut-brain cross talk

Frontiers in Pharmacology, 2023
Alcohol-related liver disease (ALD) from excessive alcohol intake has a unique gut microbiota profile. The disease progression-free survival in ALD patients has been associated with the degree of gut dysbiosis.
Lin Zhu, Yixuan Wang, Calvin Q. Pan, Calvin Q. Pan, Huichun Xing, Huichun Xing   +5 more
doaj   +1 more source

Mortality in England and Wales attributable to current alcohol consumption. [PDF]

, 2001
STUDY OBJECTIVE: To estimate the number of deaths attributable to current alcohol consumption levels in England and Wales by age and sex. DESIGN: Epidemiological approach using published relative risks and population data.
Britton, A, McPherson, K
core   +4 more sources

Public awareness of the link between alcohol and cancer in England in 2015: A population-based survey [PDF]

, 2016
Background: Public knowledge of the association between alcohol and cancer is reported to be low. We aimed to provide up-to-date evidence for England regarding awareness of the link between alcohol and different cancers and to determine whether ...
A Field, B Milton, Balance, Balance, Balance, D Hosmer, D Praud, Department for Communities and Local Government, Department of Health, DM Parkin, DW Johnston, Elena Gomes de Matos, ER Miller, F Merletti, G Corrao, G Lyratzopoulos, H Dixon, HK Seitz, HSCIC, International Agency for Research into Cancer, J Bowden, J Zhao, Jessica Li, John Holmes, K Bush, K Robb, Lucie Hooper, Lucy Gavens, M Wakefield, Melanie Lovatt, Office for National Statistics, P Buykx, Penny Buykx, Petra Meier, S Michie, SC Sanderson, V Bagnardi, V Bagnardi, WL Lipworth, World Cancer Research Fund International/American Institute for Cancer Research, Y Meng   +40 more
core   +5 more sources

Fibrosis and alcohol-related liver disease [PDF]

Journal of Hepatology, 2019
Histological fibrosis stage is one of the most important prognostic factors in compensated and decompensated alcohol-related liver disease (ALD). Morphological assessment of fibrosis is useful for patient stratification, enabling individualised management, and for evaluation of treatment effects in clinical studies.
Lackner, Carolin, Tiniakos, Dina
openaire   +3 more sources

Alcoholic Liver Disease in Asia, Europe, and North America [PDF]

, 2016
Alcoholic liver diseases comprise a spectrum of clinical disorders and changes in liver tissue that can be detected by pathology analysis. These range from steatosis to more severe signs and symptoms of liver disease associated with inflammation, such as
Haber, Paul, Liangpunsakul, Suthat, McCaughan, Geoffrey W.   +2 more
core   +1 more source

Epidemiology of Alcoholic Liver Disease in Korea

The Korean Journal of Gastroenterology, 2020
The harmful use of alcohol is associated with significant medical and socioeconomic burdens responsible for approximately 6% of all deaths worldwide. In Korea, the total alcohol consumption recently decreased slightly from 14.8 L of alcohol per person on
Sung Won Lee
doaj   +1 more source