Results 31 to 40 of about 282,239 (282)

Fungi–Bacteria Correlation in Alcoholic Hepatitis Patients

Toxins, 2021
Alcohol-related liver disease is one of the most prevalent types of chronic liver diseases globally. Alcohol-related liver disease begins with fatty liver, which further develops into hepatic inflammation, hepatocyte injury, and progresses to fibrosis ...
Bei Gao, Xinlian Zhang, Bernd Schnabl
doaj   +1 more source

Integrated Care of Alcohol-Related Liver Disease [PDF]

Journal of Clinical and Experimental Hepatology, 2022
Alcohol-related liver disease (ALD) is the medical manifestation of alcohol use disorder, a prevalent psychiatric condition. Acute and chronic manifestations of ALD have risen in recent years especially in young people and ALD is now a leading indication of liver transplantation (LT) worldwide. Such alarming trends raise urgent and unanswered questions
Gerald S. Winder, Anne C. Fernandez, Jessica L. Mellinger   +2 more
openaire   +2 more sources

Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication⋆

JHEP Reports, 2021
Background & Aims: In experimental models, alcohol induces acute changes in lipid metabolism that cause hepatocyte lipoapoptosis and inflammation. Here we study human hepatic lipid turnover during controlled alcohol intoxication.
Mads Israelsen, Min Kim, Tommi Suvitaival, Bjørn Stæhr Madsen, Camilla Dalby Hansen, Nikolaj Torp, Kajetan Trost, Maja Thiele, Torben Hansen, Cristina Legido-Quigley, Aleksander Krag   +10 more
doaj   +1 more source

Elevated endotoxin levels in non-alcoholic fatty liver disease [PDF]

, 2010
Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty ...
Ashour, E., Steven J Creely, Youssef-Elabd, E., Youssef-Elabd, Elham M., Harte, A., Abdalla, M., Creely, S., Ashour Esmat, da Silva, Nancy F., McTernan Philip G, Mohga S Abdalla, Day, C.P., Day, Christopher Paul, Billyard, T., Burt, Alastair D., Burt Alastair D, Philip G McTernan, Kumar, S., Elham M Youssef-Elabd, da Silva, N.F., Alison L Harte, Burt, A.D., Nancy F da Silva, Amin, Ashraf I., Tripathi, Gyanendra, Sharada, H., Burt, A., McTernan, P. G., Billyard, Thomas, da Silva, N., Harte, A.L., Day Christopher P, Youssef-Elabd Elham M, Tripathi Gyanendra, Alastair D Burt, Sharada, Hayat M., Hayat M Sharada, Kumar Sudhesh, Abdalla Mohga S, Sharada, H.M., Day, C., Abdalla, Mohga S., Sudhesh Kumar, Creely, S.J., McGee Kirsty C, Esmat Ashour, McTernan, P., Abdalla, M.S., Tripathi, G., McGee, K.C., Youssef-Elabd, E.M., Kirsty C McGee, Christopher P Day, Ashour, Esmat, McGee, K., Billyard Thomas, Gyanendra Tripathi, Thomas Billyard, Kumar, Sudhesh, Amin Ashraf I, Amin, A., da Silva Nancy F, Harte, A. L., Ashraf I Amin, McTernan, P.G., Creely, Steven J., McGee, K. C., Harte Alison L, Creely Steven J, Sharada Hayat M, Amin, A.I.   +70 more
core   +1 more source

Regulating Intestinal Microbiota in the Prevention and Treatment of Alcohol-Related Liver Disease

Canadian Journal of Gastroenterology and Hepatology, 2020
When alcohol-related liver disease occurs, the number and composition ratio of intestinal microorganisms will accordingly change. The alcohol-induced changes in the intestinal microbiota play a pivotal role in the process of developing the alcohol ...
Xin Chi, Calvin Q. Pan, Shunai Liu, Danying Cheng, Ziwen Cao, Huichun Xing   +5 more
doaj   +1 more source

Epidemiology of Alcohol-associated Liver Disease

, 2021
Alcohol-associated liver disease (ALD) is a consequence of excessive alcohol use. It comprises a spectrum of histopathologic changes ranging from simple steatosis, steatohepatitis, and cirrhosis to hepatocellular carcinoma.
Han, Sen, Ma, Jing, Zhang, Ting, Chandler, Kristina, Yang, Zhihong, Liangpunsakul, Suthat   +5 more
core   +1 more source

Gut microbiota in alcohol-related liver disease: pathophysiology and gut-brain cross talk

Frontiers in Pharmacology, 2023
Alcohol-related liver disease (ALD) from excessive alcohol intake has a unique gut microbiota profile. The disease progression-free survival in ALD patients has been associated with the degree of gut dysbiosis.
Lin Zhu, Yixuan Wang, Calvin Q. Pan, Calvin Q. Pan, Huichun Xing, Huichun Xing   +5 more
doaj   +1 more source

Mortality in England and Wales attributable to current alcohol consumption. [PDF]

, 2001
STUDY OBJECTIVE: To estimate the number of deaths attributable to current alcohol consumption levels in England and Wales by age and sex. DESIGN: Epidemiological approach using published relative risks and population data.
Britton, A, McPherson, K
core   +1 more source

Alcohol and premature death in Estonian men: a study of forensic autopsies using novel biomarkers and proxy informants. [PDF]

, 2012
BACKGROUND: Alcohol makes an important contribution to premature mortality in many countries in Eastern Europe, including Estonia. However, the full extent of its impact, and the mechanisms underlying it, are challenging issues to research.
Tõnisson, Mailis, McKee, Martin, Paerna, K, Helander, A,, Pärna, Kersti, Leon, DA, Lang, K, McKee Martin, Väli, Marika, Tuusov, J, Ringmets, I, Väli Marika, Tuusov Jana, Lang, Katrin, Vaeli, M, Tõnisson Mailis, Lang Katrin, Ringmets, Inge, Ringmets Inge, Helander Anders, Leon, David A, Helander, Anders, Pärna Kersti, Leon David A, McKee, M, Tonisson, M, Tuusov, Jana   +26 more
core   +1 more source

Genetic Variants of Alcohol Metabolizing Enzymes and Alcohol-Related Liver Cirrhosis Risk

, 2021
Alcohol-related liver disease (ARLD) is a major public health issue caused by excessive alcohol consumption. ARLD encompasses a wide range of chronic liver lesions, alcohol-related liver cirrhosis being the most severe and harmful state.
Agúndez, José A. G., José A. Cornejo-García, Ladero Quesada, José María, Pedro Ayuso, García Martín, Elena Salobrar, Agúndez, José A G., Cornejo-García, José A., Elena García-Martín, Ayuso, Pedro, José María Ladero, García-Martín, Elena, Cornejo García, José A., Ladero, José María, José A. G. Agúndez   +13 more
core   +1 more source