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Steatotic liver disease [PDF]

Lancet, The
Steatotic liver disease is the overarching term for conditions characterised by abnormal lipid accumulation in the liver (liver or hepatic steatosis). Steatotic liver disease encompasses what was previously termed non-alcoholic fatty liver disease (NAFLD), which is now called metabolic dysfunction-associated steatotic liver disease (MASLD ...
Emmanuel Tsochatzis, Mads Israelsen, Sven Francque   +2 more
exaly   +11 more sources

Steatotic Liver Disease: Metabolic Dysfunction, Alcohol, or Both?

Biomedicines, 2023
Non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD), both of them accounting for fatty liver disease (FLD), are among the most common chronic liver diseases globally, contributing to substantial public health burden.
Katharina Staufer, Rudolf E. Stauber
doaj   +4 more sources

Metabolic dysfunction-associated steatotic liver disease

Tungs’ Medical Journal
As the prevalence of obesity increases globally, the incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) also increases in both developed and developing countries.
Chieh Chen, Da-Ming Liao
doaj   +9 more sources

Phosphatidylethanol in steatotic liver disease [PDF]

Journal of Hepatology
Steatotic liver disease (SLD) encompasses metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and their combination (MetALD). Distinguishing these subclasses relies on accurately assessing current alcohol intake, particularly as subclass-specific drug therapies become available.
Mads Israelsen, Nikolaj Christian Torp, Aleksander Krag   +2 more
exaly   +3 more sources

Waiting for the changes after the adoption of steatotic liver disease [PDF]

Clinical and Molecular Hepatology, 2023
Steatotic liver disease was suggested as an overarching term encompassing various etiologies of hepatic steatosis. Experts from multinational liver societies went through the Delphi process, including four rounds of surveys, and consented to adopt a new ...
Eileen L. Yoon, Dae Won Jun
doaj   +3 more sources

Implications of the new nomenclature of steatotic liver disease and definition of metabolic dysfunction‐associated steatotic liver disease [PDF]

Alimentary Pharmacology & Therapeutics, 2023
SummaryBackgroundThe American and European liver associations have endorsed new nomenclature of steatotic liver disease (SLD) and definition of metabolic dysfunction‐associated steatotic liver disease (MASLD).AimsTo review the historical development leading to the changes and to discuss the implications of the changes on research and clinical ...
Rohit Loomba, Vincent Wai‐Sun Wong
openaire   +5 more sources

Metabolic Dysfunction–Associated Steatotic Liver Disease, Alcohol Consumption, and the Risk of Atrial Fibrillation: A Nationwide Population‐Based Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The recent reclassification of steatotic liver disease into metabolic dysfunction–associated steatotic liver disease (MASLD) and metabolic dysfunction‐associated alcohol‐related liver disease has highlighted their potential cardiovascular ...
Minkwan Kim, Minkook Son, Sang Yi Moon, Yang Hyun Baek   +3 more
doaj   +3 more sources

Changes in m6A in Steatotic Liver Disease

Genes, 2023
Fatty liver disease is one of the major causes of morbidity and mortality worldwide. Fatty liver includes non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), now replaced by a consensus group as metabolic dysfunction-associated steatotic liver disease (MASLD).
Belinda J. Petri, Matthew C. Cave, Carolyn M. Klinge   +2 more
openaire   +2 more sources

Necroptosis in ischemia-reperfusion injury of lean and steatotic livers

Liver Research, 2019
Hepatic ischemia-reperfusion (IR) injury is a major complication during liver transplantation, liver resection, and other clinical situations. Increased hepatic IR injury in steatotic livers is a major reason for rejecting the use of steatotic livers for
Hua Sun, Tara McKeen, Hua Wang, Hong-Min Ni   +3 more
doaj   +1 more source

NUPR1 downregulation-mediated impairment of macrophage oxidative phosphorylation participates in the pathogenesis of ulcerative colitis

陆军军医大学学报
Objective Macrophages are key cellular contributors to the development and progression of ulcerative colitis (UC), and their functional state is closely related to oxidative phosphorylation (OXPHOS) capacity. However, changes in macrophage OXPHOS levels
YU Sirui, CHAI Jin
doaj   +1 more source