Results 1 to 10 of about 22,186 (114)

Steatotic Liver Disease: Metabolic Dysfunction, Alcohol, or Both?

open access: yesBiomedicines, 2023
Non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD), both of them accounting for fatty liver disease (FLD), are among the most common chronic liver diseases globally, contributing to substantial public health burden.
Katharina Staufer, Rudolf E. Stauber
doaj   +3 more sources

Waiting for the changes after the adoption of steatotic liver disease [PDF]

open access: yesClinical and Molecular Hepatology, 2023
Steatotic liver disease was suggested as an overarching term encompassing various etiologies of hepatic steatosis. Experts from multinational liver societies went through the Delphi process, including four rounds of surveys, and consented to adopt a new ...
Eileen L. Yoon, Dae Won Jun
doaj   +1 more source

Necroptosis in ischemia-reperfusion injury of lean and steatotic livers

open access: yesLiver Research, 2019
Hepatic ischemia-reperfusion (IR) injury is a major complication during liver transplantation, liver resection, and other clinical situations. Increased hepatic IR injury in steatotic livers is a major reason for rejecting the use of steatotic livers for
Hua Sun   +3 more
doaj   +1 more source

NUPR1 downregulation-mediated impairment of macrophage oxidative phosphorylation participates in the pathogenesis of ulcerative colitis

open access: yes陆军军医大学学报
Objective Macrophages are key cellular contributors to the development and progression of ulcerative colitis (UC), and their functional state is closely related to oxidative phosphorylation (OXPHOS) capacity. However, changes in macrophage OXPHOS levels
YU Sirui, CHAI Jin
doaj   +1 more source

Targeting the gut microbiota-bile acid axis: Therapeutic strategies for cholestatic liver disease and metabolic dysfunction-associated steatotic liver disease

open access: yesEngMedicine
Cholestatic liver disease (CSLD) and metabolic dysfunction-associated steatotic liver disease (MASLD) are both associated with abnormal bile acid (BA) metabolism and have a steadily increasing incidence and prevalence worldwide.
Xingtao Zhao   +5 more
doaj   +1 more source

Characteristics of Metabolic Dysfunction-Associated Steatotic Liver Disease and Its Risk for Hepatic Fibrosis in 476,124 Korean Adults: A Cross-Sectional Study [PDF]

open access: yesEndocrinology and Metabolism
As the new terminology of metabolic dysfunction-associated steatotic liver disease (MASLD) and MASLD with increased alcohol intake (MetALD) has emerged, the clinical significance of MASLD is increasing.
Da Yeon Lee   +9 more
doaj   +1 more source

Multi-omics technologies in the study of clinical heterogeneity of metabolic associated fatty liver disease

open access: yesNeike lilun yu shijian
Metabolic associated fatty liver disease (MAFLD) is the most prevalent chronic liver disease worldwide and has become an important public health issue. MAFLD not only impairs liver function but is also closely associated with an increased risk of multi ...
Jingjing DING, Jin CHAI
doaj   +1 more source

Aluminum adjuvant promotes liver inflammation and fibrosis in mice: A novel approach to establish a liver fibrosis animal model

open access: yesLiver Research
Background and aims: Liver fibrosis is a prevalent pathological stage of various chronic liver diseases and has the potential to progress to liver cirrhosis and hepatocellular carcinoma.
Zhixian Zhu   +6 more
doaj   +1 more source

Mapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region

open access: yesFrontiers in Medicine
BackgroundArtificial intelligence (AI) is increasingly relevant to hepatology, yet real-world adoption in the Middle East and North Africa (MENA) is uncertain.
Mohamed El-Kassas   +256 more
doaj   +1 more source

Small Steatotic HCC: A Radiological Variant Associated With Improved Outcome After Ablation

open access: yesHepatology Communications, 2021
Percutaneous thermal ablation is a validated treatment option for small hepatocellular carcinoma (HCC). Steatotic HCC can be reliably detected by magnetic resonance imaging.
Margaux Hermida   +10 more
doaj   +1 more source

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