Results 21 to 30 of about 5,456,142 (288)

Cardiometabolic Biomarkers for Disease Severity Prediction in Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

open access: yesKaohsiung J Med Sci
ABSTRACT The impacts of cardiometabolic risk factors (CMRFs) and the biomarkers on disease severity in metabolic dysfunction‐associated steatotic liver disease (MASLD) remain elusive. Accordingly, a multicenter study by recruiting MASLD patients from a nationwide registry database was conducted with a total of 2882 MASLD patients (54.1% males, mean age 
Huang JF   +14 more
europepmc   +2 more sources

Critical appraisal of metabolic dysfunction-associated steatotic liver disease: Implication of Janus-faced modernity [PDF]

open access: yes, 2023
The existing term non-alcoholic fatty liver disease (NAFLD) has raised substantial concerns due to its inherent disadvantages of using exclusionary diagnostic criteria and the stigmatizing word ‘fatty.’ Three pan-national liver associations set out to ...
Won Kim, Joon Ho Moon, Gi-Ae Kim
core   +2 more sources

Targeting the gut microbiota-bile acid axis: Therapeutic strategies for cholestatic liver disease and metabolic dysfunction-associated steatotic liver disease

open access: yesEngMedicine
Cholestatic liver disease (CSLD) and metabolic dysfunction-associated steatotic liver disease (MASLD) are both associated with abnormal bile acid (BA) metabolism and have a steadily increasing incidence and prevalence worldwide.
Xingtao Zhao   +5 more
doaj   +1 more source

Characteristics of Metabolic Dysfunction-Associated Steatotic Liver Disease and Its Risk for Hepatic Fibrosis in 476,124 Korean Adults: A Cross-Sectional Study [PDF]

open access: yesEndocrinology and Metabolism
As the new terminology of metabolic dysfunction-associated steatotic liver disease (MASLD) and MASLD with increased alcohol intake (MetALD) has emerged, the clinical significance of MASLD is increasing.
Da Yeon Lee   +9 more
doaj   +1 more source

Multi-omics technologies in the study of clinical heterogeneity of metabolic associated fatty liver disease

open access: yesNeike lilun yu shijian
Metabolic associated fatty liver disease (MAFLD) is the most prevalent chronic liver disease worldwide and has become an important public health issue. MAFLD not only impairs liver function but is also closely associated with an increased risk of multi ...
Jingjing DING, Jin CHAI
doaj   +1 more source

Aluminum adjuvant promotes liver inflammation and fibrosis in mice: A novel approach to establish a liver fibrosis animal model

open access: yesLiver Research
Background and aims: Liver fibrosis is a prevalent pathological stage of various chronic liver diseases and has the potential to progress to liver cirrhosis and hepatocellular carcinoma.
Zhixian Zhu   +6 more
doaj   +1 more source

Imaging Evaluation for Steatotic Liver Disease

open access: yesKorean Journal of Radiology
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease, is the fastest-growing cause of chronic liver disease worldwide, affecting approximately 30% of the global population. Imaging is vital for detecting, quantifying, and monitoring hepatic steatosis-the defining abnormality of MASLD-and
Shin Mei Chan   +9 more
openaire   +3 more sources

Dose adaptation of drugs in patients with liver disease [PDF]

open access: yes, 2009
A detailed introduction into the topic was obtained by developing a German-language online course named “Dose adjustment in Patients with Liver Disease” for the “Swiss Virtual Campus” in collaboration with PNN AG, a spin-off company of the ETH Zurich.
Schlatter-Häner, Chantal
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Mapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region

open access: yesFrontiers in Medicine
BackgroundArtificial intelligence (AI) is increasingly relevant to hepatology, yet real-world adoption in the Middle East and North Africa (MENA) is uncertain.
Mohamed El-Kassas   +256 more
doaj   +1 more source

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