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Alcohol use and mental health during COVID-19 lockdown: A cross-sectional study in a sample of UK adults
Drug and Alcohol Dependence, 2020 Background The aim was to examine the correlates of increased alcohol consumption during the COVID-19 pandemic-related restrictions that were implemented in a sample of UK adults. Methods This paper presents analyses of data from a cross-sectional study. L. Jacob, Lee Smith, Nicola C. Armstrong, Anita Yakkundi, Y. Barnett, L. Butler, Daragh T. McDermott, A. Koyanagi, J. Shin, Jacob D. Meyer, J. Firth, O. Remes, G. López-Sánchez, M. Tully +13 moresemanticscholar +1 more sourceCutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna +12 morewiley +1 more sourceMagnetic Resonance Spectroscopy of the Brain in Alcohol Abuse. [PDF]
, 1995 Magnetic resonance (MR) technology produces data on brain structure and activity without relying on radiation or invasive surgery. Magnetic resonance imaging (MRI) creates images, and magnetic resonance spectroscopy (MRS) produces spectra based on the ...Fein, George, Meyerhoff, Dieter J, Weiner, Michael W +2 morecore Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
PLoS ONE, 2018 Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown.M. Feitosa, A. Kraja, D. Chasman, Y. Sung, T. Winkler, I. Ntalla, Xiuqing Guo, N. Franceschini, Ching-Yu Cheng, X. Sim, D. Vojinovic, J. Marten, S. Musani, Changwei Li, A. Bentley, Michael R. Brown, K. Schwander, Melissa A. Richard, R. Noordam, H. Aschard, T. Bartz, L. Bielak, R. Dorajoo, Virginia Fisher, F. Hartwig, A. Horimoto, K. Lohman, A. Manning, T. Rankinen, A. Smith, S. Tajuddin, M. Wojczynski, Maris Alver, M. Boissel, Q. Cai, A. Campbell, Jin-Fang Chai, Xu Chen, J. Divers, Chuan Gao, A. Goel, Y. Hagemeijer, S. Harris, M. He, F. Hsu, A. Jackson, M. Kähönen, A. Kasturiratne, P. Komulainen, Brigitte Kühnel, F. Laguzzi, J. Luan, N. Matoba, I. Nolte, S. Padmanabhan, Muhammad B. Riaz, R. Rueedi, A. Robino, M. A. Said, R. Scott, T. Sofer, A. Stančáková, F. Takeuchi, B. Tayo, P. J. van der Most, T. Varga, V. Vitart, Yajuan Wang, E. Ware, H. Warren, S. Weiss, W. Wen, L. Yanek, Weihua Zhang, Jinghua Zhao, S. Afaq, N. Amin, M. Amini, D. Arking, T. Aung, E. Boerwinkle, I. Borecki, U. Broeckel, Morris J. Brown, M. Brumat, G. Burke, M. Canouil, A. Chakravarti, S. Charumathi, Yii-Der Ida Chen, J. Connell, A. Correa, L. de las Fuentes, R. de Mutsert, H. J. de Silva, Xuan Deng, Jingzhong Ding, Qing Duan, C. Eaton, G. Ehret, R. N. Eppinga, E. Evangelou, J. Faul, S. Felix, N. Forouhi, T. Forrester, O. Franco, Y. Friedlander, I. Gandin, He Gao, M. Ghanbari, B. Gigante, C. Gu, D. Gu, S. Hagenaars, G. Hallmans, T. Harris, Jiang He, S. Heikkinen, C. Heng, M. Hirata, B. Howard, M. Ikram, U. John, T. Katsuya, C. Khor, T. Kilpeläinen, W. Koh, J. Krieger, S. Kritchevsky, M. Kubo, J. Kuusisto, T. Lakka, C. Langefeld, C. Langenberg, L. Launer, B. Lehne, C. Lewis, Yize Li, Shiow J. Lin, Jianjun Liu, Jingmin Liu, M. Loh, T. Louie, R. Mägi, C. McKenzie, T. Meitinger, A. Metspalu, Y. Milaneschi, L. Milani, K. Mohlke, Y. Momozawa, M. Nalls, C. Nelson, N. Sotoodehnia, J. Norris, Jeffery R O'connell, N. Palmer, T. Perls, N. Pedersen, A. Peters, P. Peyser, N. Poulter, L. Raffel, O. Raitakari, Kathryn Roll, L. Rose, F. Rosendaal, J. Rotter, C. Schmidt, P. Schreiner, N. Schupf, W. Scott, P. Sever, Yuan Shi, S. Sidney, M. Sims, C. Sitlani, Jennifer A. Smith, H. Snieder, J. Starr, K. Strauch, H. Stringham, N. Tan, Hua Tang, K. Taylor, Y. Teo, Y. Tham, S. Turner, A. Uitterlinden, P. Vollenweider, M. Waldenberger, Lihua Wang, Y. X. Wang, W. Wei, Christine A. Williams, Jie Yao, Caizheng Yu, Jian-Min Yuan, Wei Zhao, A. Zonderman, D. Becker, M. Boehnke, D. Bowden, J. Chambers, I. Deary, T. Esko, M. Farrall, P. Franks, B. Freedman, P. Froguel, P. Gasparini, C. Gieger, J. Jonas, Y. Kamatani, N. Kato, J. Kooner, Z. Kutalik, M. Laakso, C. Laurie, K. Leander, T. Lehtimäki, L. Study, P. Magnusson, A. Oldehinkel, B. Penninx, O. Polašek, D. Porteous, R. Rauramaa, N. Samani, J. Scott, X. Shu, P. van der Harst, L. Wagenknecht, N. Wareham, H. Watkins, D. Weir, A. R. Wickremasinghe, Tangchun Wu, W. Zheng, C. Bouchard, K. Christensen, M. Evans, V. Gudnason, B. Horta, S. Kardia, Yongmei Liu, A. Pereira, B. Psaty, P. Ridker, R. V. van Dam, W. Gauderman, Xiaofeng Zhu, D. Mook-Kanamori, M. Fornage, C. Rotimi, L. Cupples, T. Kelly, E. Fox, C. Hayward, C. V. van Duijn, E. Tai, T. Wong, C. Kooperberg, W. Palmas, K. Rice, A. Morrison, P. Elliott, M. Caulfield, P. Munroe, D. Rao, M. Province, D. Levy +272 moresemanticscholar +1 more sourceNetwork Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background
Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa +12 morewiley +1 more sourcePredicting development of adolescent drinking behaviour from whole brain structure at 14 years of age [PDF]
, 2019 Adolescence is a common time for initiation of alcohol use and development of alcohol use disorders. The present study investigates neuroanatomical predictors for trajectories of future alcohol use based on a novel voxel-wise whole-brain structural ...Babor, Boecker-Schlier, Brain Development Cooperative Group, Brenhouse, Casanova, Dager, Durston, Goddings, Goodkind, Goodman, Heinz, Jacobus, Kievit, Koob, Kühn, Kühn, Little, Madhyastha, McArdle, Muthen, Nees, Norman, Olsen, Ostby, Raz, Ritchie, Schumann, Squeglia, Squeglia, Whelan +29 morecore +1 more sourceImprisonment of opioid‐dependent people in New South Wales, Australia, 2000–2012: a retrospective linkage study
Australian and New Zealand Journal of Public Health, 2014 Objective: There are few data about the incarceration of opioid‐dependent people involving large representative cohorts. We aimed to determine the prevalence and duration of incarceration in a large cohort of opioid‐dependent people in Australia using ...Louisa Degenhardt, Sarah Larney, Natasa Gisev, Judy Trevena, Lucy Burns, Jo Kimber, Marian Shanahan, Tony Butler, Richard P. Mattick, Don Weatherburn +9 moredoaj +1 more sourceMultidimensional Quality of Life Across the Spectrum of Alcohol Use Behavior
Psychiatric Research and Clinical Practice, 2022 Objective Quality of life (QoL) is inversely associated with alcohol misuse and is a key measure by which recovery from alcohol use disorder (AUD) might be assessed. Yet, the determinants of QoL are scarcely known. The authors examined three ways through Jeremy W. Luk, Vijay A. Ramchandani, Nancy Diazgranados, Melanie L. Schwandt, Tommy Gunawan, David T. George, David Goldman +6 moredoaj +1 more source