Results 91 to 100 of about 4,755,709 (403)

Alcohol outlets near schools in a midsize Romanian city : prevalence and characteristics [PDF]

, 2010
Objective: alcohol availability is one of the strongest predictors of adolescent alcohol use, and subsequent harm. Alcohol outlets near schools are an important indicator of three types of availability related to adolescent alcohol use; physical (number),
Dalen, Wim E. van, Hoof, Joris J. van, Reijlink, Lian M.J.   +2 more
core   +3 more sources

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Social and Cultural Contexts of Alcohol Use: Influences in a Social-Ecological Framework. [PDF]

, 2016
Alcohol use and misuse account for 3.3 million deaths every year, or 6 percent of all deaths worldwide. The harmful effects of alcohol misuse are far reaching and range from individual health risks, morbidity, and mortality to consequences for family ...
Sudhinaraset, May, Takeuchi, David T, Wigglesworth, Christina   +2 more
core   +1 more source

Midwives’ engagement in smoking- and alcohol-prevention in prenatal care before and after the introduction of practice guidelines in Switzerland : comparison of survey findings from 2008 and 2018 [PDF]

, 2020
Background: Evidence suggests that cigarette smoking and alcohol consumption during pregnancy negatively impacts fetal health. Health agencies across countries have developed specific guidelines for health professionals in perinatal care to strengthen ...
Gkiouleka, Anna, Grob, Alexander, Lemola, Sakari, Meyer-Leu, Yvonne, Tritten Schwarz, Katharina, Urfer-Maurer, Natalie   +5 more
core   +3 more sources

Alcohol use and dementia: a systematic scoping review

Alzheimer's Research & Therapy, 2019
Alcohol use has been identified as a risk factor for dementia and cognitive decline. However, some patterns of drinking have been associated with beneficial effects.
J. Rehm, O. Hasan, S. Black, K. Shield, M. Schwarzinger   +4 more
semanticscholar   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Life outcomes in adults living with FASD in a rural South African community: A follow-up study

African Journal of Disability
Background: Even though adults with foetal alcohol spectrum disorder (FASD) are at risk of negative life outcomes, there is no published evidence of this in South Africa, which has the highest estimated FASD prevalence rate globally.
Mandi Broodryk, Jaco G. Louw, Debbie Acker, Denis L. Viljoen, Leana Olivier   +4 more
doaj   +1 more source

The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics

Cell Death Discovery, 2023
The proliferation and differentiation of hepatic progenitor cells (HPCs) drive the homeostatic renewal of the liver under diverse conditions. Liver regeneration is associated with an increase in Axin2+Cnr1+ HPCs, along with a marked increase in the ...
Bani Mukhopadhyay, Kellie Holovac, Kornel Schuebel, Partha Mukhopadhyay, Resat Cinar, Sindhu Iyer, Cheryl Marietta, David Goldman, George Kunos   +8 more
doaj   +1 more source

Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students [PDF]

, 2017
Background: Genetic factors impact alcohol use behaviors and these factors may become increasingly evident during emerging adulthood. Examination of the effects of individual variants as well as aggregate genetic variation can clarify mechanisms ...
Adkins, Amy, Aliev, Fazil, Cho, Seung B., Cooke, Megan E., Dick, Danielle M., Edwards, Alexis C., Kendler, Kenneth S., Kitchens, James N., Neale, Zoe, Pedersen, Kimberly, Riley, Brien P., Salvatore, Jessica E., Savage, Jeanne E., Sun, Cuie, Webb, Bradley T., Williamson, Vernell S., Wolen, Aaron R.   +16 more
core   +2 more sources

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source