Results 101 to 110 of about 4,496,597 (381)

Trends in Adult Alcohol Use and Binge Drinking in the Early 21st‐Century United States: A Meta‐Analysis of 6 National Survey Series

Alcoholism: Clinical and Experimental Research, 2018
BACKGROUND Recent trends in alcoholic liver disease, alcohol-related emergency room admissions, and alcohol use disorder prevalence as measured by general-population surveys have raised concerns about rising alcohol-related morbidity and mortality in the
R. Grucza, K. Sher, W. Kerr, Melissa J. Krauss, Camillia K. Lui, Yoanna E McDowell, Sarah M. Hartz, G. Virdi, L. Bierut   +8 more
semanticscholar   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Imprisonment of opioid‐dependent people in New South Wales, Australia, 2000–2012: a retrospective linkage study

Australian and New Zealand Journal of Public Health, 2014
Objective: There are few data about the incarceration of opioid‐dependent people involving large representative cohorts. We aimed to determine the prevalence and duration of incarceration in a large cohort of opioid‐dependent people in Australia using ...
Louisa Degenhardt, Sarah Larney, Natasa Gisev, Judy Trevena, Lucy Burns, Jo Kimber, Marian Shanahan, Tony Butler, Richard P. Mattick, Don Weatherburn   +9 more
doaj   +1 more source

Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement

Journal of the American Medical Association (JAMA), 2018
Importance Excessive alcohol use is one of the most common causes of premature mortality in the United States. From 2006 to 2010, an estimated 88 000 alcohol-attributable deaths occurred annually in the United States, caused by both acute conditions (eg,
S. Curry, A. Krist, D. Owens, M. Barry, A. Caughey, K. Davidson, Chyke A Doubeni, J. Epling, A. Kemper, Martha Y. Kubik, C. Landefeld, C. Mangione, Michael Silverstein, M. Simon, Chien-Wen Tseng, J. Wong   +15 more
semanticscholar   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

The impact of changes in opioid dependency treatment upon COVID-19 transmission in Sydney, Australia: a retrospective longitudinal observational study

BMC Public Health
Background In April 2020, in response to the COVID-19 public health emergency, South Eastern Sydney Local Health District (SESLHD) Drug and Alcohol services modified their delivery of opioid dependency treatment (ODT) to reduce spread of COVID-19 and ...
Benjamin T. Trevitt, Victoria Hayes, Rachel Deacon, Llewellyn Mills, Apo Demirkol, Nicholas Lintzeris   +5 more
doaj   +1 more source

User-centered design of contingency management for implementation in opioid treatment programs: a qualitative study

BMC Health Services Research, 2019
Background Contingency management (CM) is one of the only behavioral interventions shown to be effective for the treatment of opioid use disorders when delivered alone and in combination with pharmacotherapy.
Sara J. Becker, Kelli Scott, Cara M. Murphy, Melissa Pielech, Samantha A. Moul, Kimberly R. Yap, Bryan R. Garner   +6 more
doaj   +1 more source

The impact of poly-traumatization on treatment outcomes in young people with substance use disorders

BMC Psychiatry, 2021
Background It is believed that clients with psychological trauma experiences have a poor prognosis with regard to treatment participation and outcomes for substance use disorders.
Sidsel Karsberg, Morten Hesse, Michael Mulbjerg Pedersen, Ruby Charak, Mads Uffe Pedersen   +4 more
doaj   +1 more source

Alcohol consumption in young adults: the role of multisensory imagery. [PDF]

, 2013
Accepted 19.11.2013Little is known about the subjective experience of alcohol desire and craving in young people. Descriptions of alcohol urges continue to be extensively used in the everyday lexicon of young, non-dependent drinkers. Elaborated Intrusion
Andrade, J, Connor, JP, Drennan, J, Feeney, GFX, Fry, M-L, Gullo, MJ, Kavanagh, DJ, May, J, Previte, J, Tjondronegoro, D, White, AM   +10 more
core   +1 more source

Evidence Based Treatment for Excessive Alcohol Consumption and Concurrent Hypertension [PDF]

, 2020
Purpose. Excessive alcohol consumption is a preventable risk factor for hypertension, heart disease, and stroke. Though alcohol-related deaths number 88,000 annually in the U.S., alcohol use has the lowest treatment rate of behavioral health disorders at
Ward, Kimberly Ann
core   +1 more source