Results 121 to 130 of about 4,496,597 (381)

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

The web‐based self‐reported survey of Alcohol Use Disorders Identification Test and associated factors in Japan

open access: yesPCN Reports
Aim While considerable data on the alcohol drinking behavior of the general population are available for the United States and Europe, data from Asian countries are scarce. We attempted to estimate the social backgrounds and other factors associated with
Tomomi Toyama   +5 more
doaj   +1 more source

Alcohol Availability and Violence: A Closer Look at Space and Time [PDF]

open access: yes, 2017
Alcohol availability plays an important role in violence. Less is known about how spatiotemporal patterns of alcohol–violence association vary across time of day and across various crime types. This study examined whether and how the associations between
Snowden, Aleksandra J.
core   +1 more source

When wanting to change is not enough: automatic appetitive processes moderate the effects of a brief alcohol intervention in hazardous-drinking college students. [PDF]

open access: yes, 2012
BACKGROUND: Research indicates that brief motivational interventions are efficacious treatments for hazardous drinking. Little is known, however, about the psychological processes that may moderate intervention success.
Ostafin, Brian D., Palfai, Tibor P.
core   +2 more sources

ALCOHOLISM [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1892
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openaire   +2 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Public librarians expand their roles of responsibilities towards community change

open access: yesTobacco Induced Diseases, 2018
Objective To reduce tobacco consumption in communities through public librarians. Methods Sri Lanka holds more than 1000 libraries and per day 100 – 200 readers visit library.
Sasanka Dharmasena   +2 more
doaj   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

Short- and long-term effects of ethanol administration in vivo on rat liver HMG-CoA reductase and cholesterol 7α-hydroxylase activities

open access: yesJournal of Lipid Research, 1977
Short- and long-term effects of ethanol on HMG-CoA reductase (EC 1.1.1.34) and cholesterol 7α-hydroxylase activities in rat liver have been investigated.
M R Lakshmanan, R L Veech
doaj  

Characterisation of two alcohol acyltransferases from kiwifruit (Actinidia spp.) reveals distinct substrate preferences. [PDF]

open access: yes, 2011
Volatile esters are key compounds of kiwifruit flavour and are formed by alcohol acyltransferases that belong to the BAHD acyltransferase superfamily.
Chervin, Christian   +4 more
core   +1 more source

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