Results 21 to 30 of about 2,077,105 (300)

COVID-19 and the drug situation in Lithuania

open access: yesJournal of Geography, Politics and Society, 2022
The application of restrictive public health measures because of COVID-19 has affected all areas of life, including drug use, drug market, and the response of law enforcement and health, education, and social care institutions to the drug phenomenon.
Evelina Pridotkienė   +4 more
doaj   +1 more source

4191 The Role of Suggestibility and Trait Anxiety in Young Adult Alcohol Use

open access: yesJournal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: The purpose of this study was to investigate how suggestibility and social susceptibility relate to alcohol use in young adult non-dependent alcohol users, and the role of trait anxiety in this relationship. We hypothesized that greater
Alexandra Cowand   +6 more
doaj   +1 more source

cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease

open access: yesBiomolecules, 2020
The importance of cyclic adenosine monophosphate (cAMP) in cellular responses to extracellular signals is well established. Many years after discovery, our understanding of the intricacy of cAMP signaling has improved dramatically.
Mohamed Elnagdy   +3 more
doaj   +1 more source

The Center of Alcohol Studies and the JOURNAL OF STUDIES ON ALCOHOL: Celebrating 50 Years

open access: yes, 1989
Copy of the article Nathan, P. E. (1989). The Center of Alcohol Studies and the Journal of Studies on Alcohol: celebrating 50 years. Journal of Studies on Alcohol, 50(4), 297–300. https://doi.org/10.15288/jsa.1989.50.297.
Nathan, Peter
core   +1 more source

Cholesterol as a modulator of cannabinoid receptor CB2 signaling

open access: yesScientific Reports, 2021
Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB2, we demonstrate that cholesterol increases basal ...
Alexei Yeliseev   +7 more
doaj   +1 more source

Studies of Alcohol: Past, Present and Future

open access: yes, 1989
Copy of the article Mendelson, J. H., & Mello, N. K. (1989). Studies of Alcohol: Past, Present and Future. Journal of Studies on Alcohol, 50(4), 293–196.
Mendelson, Jack, H., Mello, Nancy, K.
core   +1 more source

Short- and long-term effects of ethanol administration in vivo on rat liver HMG-CoA reductase and cholesterol 7α-hydroxylase activities

open access: yesJournal of Lipid Research, 1977
Short- and long-term effects of ethanol on HMG-CoA reductase (EC 1.1.1.34) and cholesterol 7α-hydroxylase activities in rat liver have been investigated.
M R Lakshmanan, R L Veech
doaj   +1 more source

Time-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans

open access: yesCommunications Biology, 2023
Combined PET imaging and mathematical simulations reveal that the rate of dopamine increase in the striatum underlies self-reports of drug “high” in response to oral and intravenous methylphenidate challenges in ...
Dardo Tomasi   +15 more
doaj   +1 more source

Sex differences in nicotine-enhanced Pavlovian conditioned approach in rats

open access: yesBiology of Sex Differences, 2019
Background Nicotine exposure enhances Pavlovian conditioned approach (PCA), or the learned approach to reward-predictive cues. While females show elevated approach to conditioned stimuli compared to males, potentially indicating heightened addiction ...
Sierra J. Stringfield   +3 more
doaj   +1 more source

Naloxone’s dose-dependent displacement of [11C]carfentanil and duration of receptor occupancy in the rat brain

open access: yesScientific Reports, 2022
The continuous rise in opioid overdoses in the United States is predominantly driven by very potent synthetic opioids, mostly fentanyl and its derivatives (fentanyls).
Yeona Kang   +14 more
doaj   +1 more source

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