Results 41 to 50 of about 3,637,487 (305)
cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease
Biomolecules, 2020 The importance of cyclic adenosine monophosphate (cAMP) in cellular responses to extracellular signals is well established. Many years after discovery, our understanding of the intricacy of cAMP signaling has improved dramatically.
Mohamed Elnagdy +3 more
doaj +1 more source
Intoxicated eyewitnesses:the effect of a fully balanced placebo design on event memory and metacognitive control [PDF]
, 2019 Few studies have examined the impact of alcohol on metacognition for witnessed events. We used a 2x2 balanced placebo design, where mock-witnesses expected and drank alcohol, did not expect but drank alcohol, did not expect nor drank alcohol, or expected
Babor T. +6 more
core +2 more sources
Alcohol outlets near schools in a midsize Romanian city : prevalence and characteristics [PDF]
, 2010 Objective: alcohol availability is one of the strongest predictors of adolescent alcohol use, and subsequent harm. Alcohol outlets near schools are an important indicator of three types of availability related to adolescent alcohol use; physical (number),
Dalen, Wim E. van +2 more
core +3 more sources
Journal of Lipid Research, 1977 Short- and long-term effects of ethanol on HMG-CoA reductase (EC 1.1.1.34) and cholesterol 7α-hydroxylase activities in rat liver have been investigated.
M R Lakshmanan, R L Veech
doaj +1 more source
Cholesterol as a modulator of cannabinoid receptor CB2 signaling
Scientific Reports, 2021 Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB2, we demonstrate that cholesterol increases basal ...
Alexei Yeliseev +7 more
doaj +1 more source
Effects of irritability on craving before and after cue exposure in abstinent alcoholic inpatients: Experimental data on subjective response and heart rate [PDF]
, 2002 Objective: Irritability is often linked with problem drinking. The aim of this study is to examine the possible influence of irritability on craving induced by a cue-exposure paradigm.
Chiang, Sonnig S. W. +2 more
core +1 more source
BMJ, 1982 Abstract There is evidence for a dose-response relationship between alcohol consumption and risk of liver cirrhosis, cancers of the oropharynx, larynx, oesophagus, rectum (beer only), liver, and female breast, and violent death, but the relationship between alcohol consumption and cardiovascular disease is more complex.
openaire +2 more sources
Sex differences in nicotine-enhanced Pavlovian conditioned approach in rats
Biology of Sex Differences, 2019 Background Nicotine exposure enhances Pavlovian conditioned approach (PCA), or the learned approach to reward-predictive cues. While females show elevated approach to conditioned stimuli compared to males, potentially indicating heightened addiction ...
Sierra J. Stringfield +3 more
doaj +1 more source
Communications Biology, 2023 Combined PET imaging and mathematical simulations reveal that the rate of dopamine increase in the striatum underlies self-reports of drug “high” in response to oral and intravenous methylphenidate challenges in ...
Dardo Tomasi +15 more
doaj +1 more source