Results 81 to 90 of about 4,496,597 (381)

Advances in the science and treatment of alcohol use disorder

Science Advances, 2019
Pharmacological and behavioral treatments exist for alcohol use disorder, but more are needed, and several are under development. Alcohol is a major contributor to global disease and a leading cause of preventable death, causing approximately 88,000 ...
K. Witkiewitz, R. Litten, L. Leggio, L. Leggio, L. Leggio   +4 more
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Different Types of Alcohol Tax and Minimum Pricing Policies: An Evidence and Policy Review

Addicta: The Turkish Journal on Addictions
To This article presents the best available evidence regarding types of alcohol taxation and alcohol pricing policies and their effectiveness in reducing alcohol harm, by reviewing scholarly and grey literature.
Jem Roberts, Katherine Severi, Peter Rice   +2 more
doaj   +1 more source

Police Alcohol-Related Services Study (PASS), Phase II: A Description of the Beliefs, Perceptions and Attitudes of Anchorage Police Department Employees [PDF]

, 2005
The principal aim of the Police Alcohol-related Services Study (PASS) was to expand knowledge about the fiscal, organizational, and cultural impact of citizen alcohol use on the Anchorage Police Department (APD).
Langworthy, Robert H., Myrstol, Brad A.
core  

Alcohol advertising: the last chance saloon [PDF]

, 2010
Research has established that alcohol advertising,1-3 like that for tobacco4 and fast food,5-7 influences behaviour. It encourages young people to drink alcohol sooner and in greater quantities.
Angus, Kathryn, Anker, Thomas, Brooks, Oona, Farrell, Tom, Hastings, Gerard, Stead, Martine   +5 more
core   +3 more sources

The Role of Stress, Trauma, and Negative Affect in Alcohol Misuse and Alcohol Use Disorder in Women

Alcohol research : current reviews, 2020
Recent evidence indicates that the United States is facing a public health crisis of alcohol misuse and alcohol use disorder (AUD), which has been fueled in part by dramatic rises in binge and heavy drinking and prevalence of AUD in women.
M. I. B. Guinle, R. Sinha
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation

Journal of Neuroinflammation, 2023
Background Neuroinflammation is a widely studied phenomenon underlying various neurodegenerative diseases. Earlier study demonstrated that pharmacological activation of GPR110 in both central and peripheral immune cells cooperatively ameliorates ...
Sharmistha Banerjee, Taeyeop Park, Yoo Sun Kim, Hee-Yong Kim   +3 more
doaj   +1 more source

Alcohol consumption among Chilean adolescents: examining individual, peer, parenting and environmental factors [PDF]

, 2013
AIMS: This study examined whether adolescents from Santiago, Chile who had never drunk alcohol differed from those who had drunk alcohol but who had never experienced an alcohol-related problem, as well as from those who had drunk and who had experienced
Bares, Cristina, Delva, Jorge, Grogan-Kaylor, Andrew, Sanhueza, Guillermo Enrique   +3 more
core   +1 more source

Alcoholic and non-alcoholic steatohepatitis [PDF]

Experimental and Molecular Pathology, 2014
This paper is based upon the “Charles Lieber Satellite Symposia” organized by Manuela G. Neuman at the Research Society on Alcoholism (RSA) Annual Meetings, 2013 and 2014. The present review includes pre-clinical, translational and clinical research that characterize alcoholic liver disease (ALD) and non-alcoholic steatohepatitis (NASH). In addition, a
Samuel W. French, Brittany Tillman, Iain H. McKillop, Murali Ganesan, Abraham Bautista, Hui Liu, Hong Shen, Devanshi Seth, Paul G. Thomes, Irina A. Kirpich, Steve Malnick, Craig J. McClain, Kusum K. Kharbanda, Radu M. Nanau, Barbara A. French, Jun Li, Mihai Opris, Manuela G. Neuman, Lawrence Cohen, Mihai Voiculescu, Helmut K. Seitz, Sebastian Mueller, Natalia A. Osna, Kyle J. Thompson, Ramon Bataller   +24 more
openaire   +3 more sources