Results 41 to 50 of about 1,119,043 (303)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Why should we ask binge drinkers if they smoke cannabis? Additive effect of alcohol and cannabis use on college students’ neuropsychological performance

Addictive Behaviors Reports, 2021
Introduction: Binge drinking (BD) and cannabis use are prevalent in European adolescents and students. BD has been shown to have a negative impact on neuropsychological functioning, but little is known about the additive effect when it is combined with ...
Simon Deniel, Maxime Mauduy, Caroline Cheam-Bernière, Nicolas Mauny, Charlotte Montcharmont, Nicolas Cabé, Anaëlle Bazire, Jessica Mange, Anne-Pascale Le Berre, Denis Jacquet, Virginie Bagneux, Pascale Leconte, Ludivine Ritz, Hélène Beaunieux   +13 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Alcohol consumption plus high-salt diet and alcohol consumption plus family history of gastric cancer: synergistic risk factors and precision screening strategies for Helicobacter pylori infection among adults in Huaihe River Basin

陆军军医大学学报
Objective Current Helicobacter pylori (HP) prevention and control strategies are mostly based on single-factor assessments, and whether alcohol consumption, high-salt diet, and family history of gastric cancer exhibit joint effects on HP infection ...
YAN Ruohan, WU Jing
doaj   +1 more source

Association between temperature, sunlight hours and alcohol consumption.

PLoS ONE, 2019
BACKGROUND:Alcohol is a major risk factor for liver cirrhosis. Recently, it was proposed that colder climate might causally lead to increased consumption of alcohol.
Hannes Hagström, Linnea Widman, Erik von Seth   +2 more
doaj   +1 more source

Associations between alcohol use and sex-specific maturation of subcortical gray matter morphometry from adolescence to adulthood: Replication across two longitudinal samples

Developmental Cognitive Neuroscience, 2023
Subcortical brain morphometry matures across adolescence and young adulthood, a time when many youth engage in escalating levels of alcohol use. Initial cross-sectional studies have shown alcohol use is associated with altered subcortical morphometry ...
Scott A. Jones, Angelica M. Morales, Gareth Harman, Kalene A. Dominguez-Savage, Sydney Gilbert, Fiona C. Baker, Massimiliano de Zambotti, David B. Goldston, Kate B. Nooner, Duncan B. Clark, Beatriz Luna, Wesley K. Thompson, Sandra A. Brown, Susan F. Tapert, Bonnie J. Nagel   +14 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Patterns of alcohol policy enforcement activities among local law enforcement agencies: A latent class analysis

, 2015
Aims: We assessed levels and patterns of alcohol policy enforcement activities among U.S. local law enforcement agencies. Design/Setting/Participants: We conducted a cross-sectional survey of a representative sample of 1,631 local law enforcement ...
Jones-Webb, Rhonda, Rutledge, Patricia C., Nelson, Toben F., Erickson, Darin J., Lenk, Kathleen M., Toomey, Traci L.   +5 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source