Results 61 to 70 of about 1,119,043 (303)

Suicide deaths and substance use in Spain between 2010 and 2022

Frontiers in Psychiatry
BackgroundSuicide is a serious public health problem that affects our entire country. The aim of this research was to study the variation in completed suicide rates between 2010 and 2022 in Spain and their relationship with the consumption of addictive ...
Gerardo Flórez, Gerardo Flórez, Ashkan Espandian, Teresa Seoane-Pillado, Noelia Llorens, José Manuel Gerpe, Pilar Saiz, Pilar Saiz, Pilar Saiz, Pilar Saiz, Pilar Saiz   +10 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Alcohol education materials: an annotated bibliography

, 1975
Cover of the book Alcohol education materials: an annotated bibliography written by Gail G. Milgram, published by the Publications Division, Rutgers Center of Alcohol Studies.Source publication: Milgram, G. G. (1975).

core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

The Interplay Between Alcohol Consumption and Cardiometabolic Risk Factors in Individuals With MASLD and MetALD

Portal Hypertension & Cirrhosis
Aims The synergistic impact of alcohol consumption and cardiometabolic risk factors (CMRFs) on liver health remains unclear. Herein, we aimed to investigate the interplay between varying levels of alcohol consumption and the number of CMRFs on all‐cause ...
Yee Hui Yeo, Fajuan Rui, Yixuan Zhu, Xiaoming Xu, Xiaoyan Ma, Wenjing Ni, Yuxiang Sun, Xinyu Hu, Chao Wu, Junping Shi, Jie Li, Philip N. Newsome   +11 more
doaj   +1 more source

Ways of thinking about alcohol use and about alcohol problems

, 1970
Manuscript of Bacon, S. D. (1970). Ways of thinking about alcohol use and about alcohol problems. In Proceedings of a conference on Public Health Teaching about Alcoholism (pp. 12-23).
Bacon, Selden D.
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Potential of Waste Biomass from the Sugar Industry as a Source of Furfural and Its Derivatives for Use as Fuel Additives in Poland

Energies, 2020
Poland is one of the leading producers of sugar from sugar beet in Europe. However, the production of sugar generates large amounts of lignocellulosic waste, in the form of beet pulp and leaves.
Magdalena Modelska, Michal J. Binczarski, Piotr Dziugan, Szymon Nowak, Zdzisława Romanowska-Duda, Adam Sadowski, Izabela A. Witońska   +6 more
doaj   +1 more source

Rutgers Center of Alcohol Studies Summer School of Alcohol and Drug Studies T-shirt (2018) - back

, 2018
Photo of a t-shirt from the Rutgers Summer Schools of Alcohol Studies provided to students each year, which became a collector's item over time.Source: T-shirt collection of the Rutgers Summer School of Alcohol ...

core   +1 more source