Results 21 to 30 of about 441,443 (264)

Alcohol Consumption, Types of Alcohol, and Parkinson's Disease.

PLoS ONE, 2013
BackgroundThe epidemiologic evidence on alcohol consumption and Parkinson's disease (PD) is equivocal. We prospectively examined total alcohol consumption and consumption of specific types of alcoholic beverage in relation to future risk of PD.MethodsThe
Rui Liu, Xuguang Guo, Yikyung Park, Jian Wang, Xuemei Huang, Albert Hollenbeck, Aaron Blair, Honglei Chen   +7 more
doaj   +1 more source

Alcohol consumption and low-risk drinking guidelines among adults: a cross-sectional analysis from Alberta’s Tomorrow Project

Health Promotion and Chronic Disease Prevention in Canada, 2017
Introduction: Moderate to heavy alcohol consumption is a risk factor for all-cause mortality and cancer incidence. Although cross-sectional data are available through national surveys, data on alcohol consumption in Alberta from a large prospective ...
Darren R. Brenner, Tiffany R. Haig, Abbey E. Poirier, Alianu Akawung, Christine M. Friedenreich, Paula J. Robson   +5 more
doaj   +1 more source

Alcohol and burden of disease in Australia: the challenge in assessing consumption

Australian and New Zealand Journal of Public Health, 2015
Objective: Alcohol consumption is one of the major avoidable risk factors for disease, illness and injury in the Australian community. Population health scientists and economists use estimates of alcohol consumption in burden of disease frameworks to ...
Rowan P. Ogeil, Robin Room, Sharon Matthews, Belinda Lloyd   +3 more
doaj   +1 more source

Alcohol consumption in cancer survivors: state of the question and proposals for the development of psychological interventions

Psicooncologia, 2018
Objective: Alcohol consumption has been established as a risk factor for cancer development consistently over the years. In cancer survivors alcohol consumption after treatment achieves significant values, and furthermore alcohol has been associated with
Francisco García-Torres, Francisco J. Alós, Rosario Castillo-Mayén   +2 more
doaj   +1 more source

Do drinking problems in the past affect current consumption?

Cadernos de Saúde Pública, 2019
: Harmful use of alcohol ranks among the top five risk factors for disease, disability and death worldwide. However, not all individuals who consume alcohol throughout life are addicted and our premise is that addiction implies a chain of consumption ...
Ana Maria Reis, Carlota Quintal, Óscar Lourenço   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The epidemiology of alcohol consumption in Ethiopia: a systematic review and meta-analysis

Substance Abuse Treatment, Prevention, and Policy, 2019
Background Globally, excessive alcohol consumption is a major public health problem and is associated with social, mental, physical and legal consequences.
Getinet Ayano, Kalkidan Yohannis, Mebratu Abraha, Bereket Duko   +3 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Alcohol consumption and risk of psoriasis: Results from observational and genetic analyses in more than 100,000 individuals from the Danish general populationCapsule Summary

JAAD International
Background: Psoriasis is associated with high alcohol consumption, but the causality of this relationship is unclear. Objective: We aimed to use a Mendelian randomization approach to investigate the causal effects of alcohol on incident psoriasis ...
Alexander Jordan, BSc, Charlotte Näslund-Koch, MD, Signe Vedel-Krogh, PhD, Stig Egil Bojesen, DMSc, Lone Skov, DMSc   +4 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source