Results 71 to 80 of about 640,292 (336)

Learning to Predict Fitness for Duty using Near Infrared Periocular Iris Images [PDF]

open access: yesarXiv, 2022
This research proposes a new database and method to detect the reduction of alertness conditions due to alcohol, drug consumption and sleepiness deprivation from Near-Infra-Red (NIR) periocular eye images. The study focuses on determining the effect of external factors on the Central Nervous System (CNS).
arxiv  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Moderate alcohol consumption and cognitive risk

open access: yesNeuropsychiatric Disease and Treatment, 2011
Edward J Neafsey, Michael A CollinsDepartment of Molecular Pharmacology and Therapeutics, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USAAbstract: We reviewed 143 papers that described the relationship between moderate drinking of
Neafsey EJ, Collins MA
doaj  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Mortality in England and Wales attributable to current alcohol consumption. [PDF]

open access: yes, 2001
STUDY OBJECTIVE: To estimate the number of deaths attributable to current alcohol consumption levels in England and Wales by age and sex. DESIGN: Epidemiological approach using published relative risks and population data.
Britton, A, McPherson, K
core   +4 more sources

Association between temperature, sunlight hours and alcohol consumption.

open access: yesPLoS ONE, 2019
BACKGROUND:Alcohol is a major risk factor for liver cirrhosis. Recently, it was proposed that colder climate might causally lead to increased consumption of alcohol.
Hannes Hagström   +2 more
doaj   +1 more source

Socioeconomic Inequalities in Alcohol and Tobacco Consumption: A National Ecological Study in Mexican Adolescents

open access: yesThe Scientific World Journal, 2023
Alcohol and cigarettes are the psychoactive substances that adolescents use most frequently. When both addictions are combined, they carry the worst burden of disease globally.
Leticia Ávila-Burgos   +8 more
doaj   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Descriptors and accounts of alcohol consumption:methodological issues piloted with female undergraduate drinkers in Scotland [PDF]

open access: yes, 2006
Excessive drinking among young women continues to attract adverse media attention and is the target of UK government-led initiatives. Reliable research on alcohol consumption is needed to inform/evaluate public health interventions.
Donaghy, Marie   +3 more
core   +2 more sources

The Effect of Alcohol Consumption on Brain Ageing: A New Causal Inference Framework for Incomplete and Massive Phenomic Data [PDF]

open access: yesarXiv, 2023
Although substance use, such as alcohol consumption, is known to be associated with cognitive decline during ageing, its direct influence on the central nervous system remains unclear. In this study, we aim to investigate the potential influence of alcohol intake frequency on accelerated brain ageing by estimating the mean potential brain-age gap (BAG)
arxiv  

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