Results 121 to 130 of about 1,349,906 (378)

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

Studies on Liver Alcohol Dehydrogenase. III. The Influence of pH and Some Anions on the Reaction Velocity Constants. [PDF]

, 1955
Hugo Theorell, Agnar P. Nygaard, Roger Bonnichsen, Artturi I. Virtanen   +3 more
openalex   +1 more source

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

Advanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen, Can Chen, Yichen Wu, Yinxue Xia, Ruijie Luo, Jiangcheng Shu, Long Chen, Zhaohui Wang, Cheng Wang, Kai Huang   +9 more
wiley   +1 more source

Alleviating acute alcoholic liver injury in mice with Bacillus subtilis co-expressing alcohol dehydrogenase and acetaldehyde dehydrogenase

Journal of Functional Foods, 2018
Alcohol consumption increases the risk of liver disease. Here, we investigated the effects of Bacillus subtilis co-expressing alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH), key enzymes in ethanol degradation, on acute alcohol-induced ...
Jing Lu, Yunbin Lyu, Mingtong Li, Jing Sun, Zhenghua Huang, Fengxia Lu, Zhaoxin Lu   +6 more
doaj  

Binding of coenzymes to yeast alcohol dehydrogenase [PDF]

Journal of the Serbian Chemical Society, 2010
In this work, the binding of coenzymes to yeast alcohol dehydrogenase (EC 1.1.1.1) were investigated. The main criterions were the change in the standard free energies for individual reaction steps, the internal equilibrium constants and the overall ...
VLADIMIR LESKOVAC, SVETLANA TRIVIĆ, DRAGINJA PERIČIN, MIRA POPOVIĆ, JULIJAN KANDRAČ   +4 more
doaj  

The use of the ethanol pathway in goldfish Carassius auratus (L.) following anoxia [PDF]

, 2001
Goldfish (Carassius auratus) were subjected, for a period of 6 weeks, to 2h progressive hypoxia followed by 6h anoxia in closed respirometers at 15 degree C.
Aleleye-Wokoma, L.P.
core  

Alcohol Dehydrogenase

Definitions, 2020

semanticscholar   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source

Astrocytes in Amyloid Generation and Alcohol Metabolism: Implications of Alcohol Use in Neurological Disorder(s)

Cells
As per the National Survey on Drug Use and Health, 10.5% of Americans aged 12 years and older are suffering from alcohol use disorder, with a wide range of neurological disorders.
Mohit Kumar, Natalie Swanson, Sudipta Ray, Shilpa Buch, Viswanathan Saraswathi, Susmita Sil   +5 more
doaj   +1 more source

Preventive effects of standardized krill oil on alcohol hangovers in a clinical trial

Journal of Functional Foods, 2022
In this study, we investigated the effect of standardized krill oil on alcohol hangover through a placebo-controlled, randomized, double-blind, and crossover clinical trial.
Woo-Hyun Kim, Hyun-Jeong Lee, Da-Yeon Lee, Chan-Yang Lee, Jeong-Ho Oh, Jeong-Eun Kim, Kiet Vu Tan, Seoung-Ki Kang, Byungkwon Kim, Seong-Bong Hong, Namkyu Yoon, Han-Joo Lee, Soon-Mi Shim   +12 more
doaj