Results 191 to 200 of about 1,349,906 (378)

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

THE PATTERN OF VIABILITY CHANGES ASSOCIATED WITH GENOTYPE FREQUENCY AT THE ALCOHOL DEHYDROGENASE LOCUS IN A POPULATION OF DROSOPHILA MELANOGASTER

, 1969
Ken-Ichi Kojima, Yoshiko N. Tobari
openalex   +2 more sources

Crystallization of Horse Liver Alcohol Dehydrogenase Complexes from Alcohol Solutions. [PDF]

, 1967
E. Zeppezauer, B.-O. Söderberg, C.-I. Brändén, Åke Åkeson, Hugo Theorell, R. Blinc, S. Paušak, L. Ehrenberg, J. Dumanović   +8 more
openalex   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Inhibition of Liver Alcohol Dehydrogenase by Amides. [PDF]

, 1961
Charles L. Woronick, Carl von Frankenberg, Berndt Sparrman, Gerd Nielsen, Hanna Nord, Aage Jart   +5 more
openalex   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Chemical Constituents from the Fruits of Amomum kravanh and Their Role in Activating Alcohol Dehydrogenase. [PDF]

Molecules, 2023
Xiong HM, Li HY, Lin ZR, Liu XM, Bai LP, Zhang W, Jiang ZH, Zhu GY.   +7 more
europepmc   +1 more source

Electronmicroscopic Demonstration of Alcohol Dehydrogenase Activity in the Frog Retina

, 1965
Shozo Nishida, Katsuyoshi Mizuno
openalex   +2 more sources

Evaluating the Performance of Ethanol Electrochemical Nanobiosensor Through Machine for Predictive Analysis of Electric Current in Self‐Powered Biosensors

Battery Energy, EarlyView.
Developing electrodes for generating electricity using human body sweating. ABSTRACT In this study, the focus is on ethanol nano biosensors based on alcohol oxidase (AOX) enzymatic reactions and the feasibility of generating electric current for biobatteries.
Afshin Farahbakhsh, Javad Mohebbi Najm Abad, Amin Hekmatmanesh, Heikki Handroos   +3 more
wiley   +1 more source

Change in the Kinetic Regime of Aggregation of Yeast Alcohol Dehydrogenase in the Presence of 2-Hydroxypropyl-β-cyclodextrin. [PDF]

Int J Mol Sci, 2023
Borzova VA, Chernikov AM, Mikhaylova VV, Kurganov BI.   +3 more
europepmc   +1 more source