Results 71 to 80 of about 2,727,544 (257)

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

open access: yesAdvanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li   +8 more
wiley   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

open access: yesAdvanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang   +10 more
wiley   +1 more source

Emotional disorders and alexithymia in patients with alcohol dependence: the role of the interhemispheric asymmetry of the brain and the type of the cerebral deficiency

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018
We undertook this observational study among 435 patients (365 men and 70 women) who were divided into 3 groups based on the severity of the brain damage (clinical features and results of neuropsychological assessment, magnetic resonance imaging ...
A. U. Tarkhan   +8 more
doaj  

Malignant catatonia and neuroleptic malignant syndrome in relation to disulfiram overdose

open access: yesIndian Journal of Psychological Medicine, 2016
Disulfiram is a widely used drug in the management of alcohol dependence syndrome as an aversive agent. Although a drug of high efficacy, it has a large number of side effects.
Kiran K Kumar   +3 more
doaj   +1 more source

A sham-controlled trial of repetitive transcranial magnetic stimulation over left dorsolateral prefrontal cortex and its effects on craving in patients with alcohol dependence

open access: yesIndustrial Psychiatry Journal, 2020
Aim: The aim of this study is to study the effects of repetitive transcranial magnetic stimulation (rTMS) therapy over the left dorsolateral prefrontal cortex (DLPFC) in craving in drug-naive male inpatients of alcohol dependence syndrome.
Shashank Raikwar   +5 more
doaj   +1 more source

Stress and neurochemical changes associated with chronic alcohol administration [PDF]

open access: yes, 2001
: There is considerable recent experimental evidence that suggests that stress plays a major role in the development of dependence on drugs of abuse, but the potential mechanisms involved are not yet fully understood.
O'Callaghan, Matthew Joseph
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A Printed Hydrogel Hybrid Electronic System With Thermoresponsive Adhesion for Neurophysiological Monitoring

open access: yesAdvanced Science, EarlyView.
This work develops a soft hybrid electronic system with printed thermoresponsive hydrogel electrodes, which enables high‐fidelity neural signal acquisition and stimulation. The system precisely assesses median and ulnar nerve injuries in clinical cases, realizing accurate diagnosis of neural impairment while ensuring customized adhesion regulation ...
Bo Pang   +13 more
wiley   +1 more source

Autoscopic Hallucination in Alcohol Dependence Syndrome: A Rare or Missed Phenomenon?

open access: yesCase Reports in Psychiatry, 2017
Autoscopic phenomenon, a psychic illusionary duplication of one’s own self, has been the subject of interest in the literature and science for years. It has been reported in various diseases of the central nervous system but with an unknown mechanism ...
Sulochana Joshi   +2 more
doaj   +1 more source

Co-morbidity of depression and disability in patients with alcohol dependence syndrome

open access: yesTelangana Journal of Psychiatry, 2019
Introduction: Alcohol Use Disorders and Depression are among the leading causes of disability in the world according to WHO. But there are limited studies assessing comorbidity of depression and disability in Alcohol dependence syndrome and whether ...
Satya Krishna Kumar Rayapureddy   +2 more
doaj   +1 more source

Reducing alcohol-exposed pregnancies; a report of the National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect [PDF]

open access: yes
"This report is a collaborative effort of the National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect (NTFFASFAE), the Centers for Disease Control and Prevention's (CDC) National Center on Birth Defects and Developmental Disabilities ...

core  

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