Results 91 to 100 of about 2,117 (125)

Controlling the alcohol-impaired driver in Scandinavia and the United States: Simple deterrence and beyond

Journal of Criminal Justice, 1984
Three papers on simple deterrence of alcohol-impaired driving (Ross, 1982; Votey, 1984; and Phillips, Ray, and Votey, 1984) were reviewed within a broad framework of control variables including: legal, technical, psychological, moral, and cultural influences.
openaire   +1 more source

Glutathione carbamoylation with S-methyl N,N-diethylthiolcarbamate sulfoxide and sulfone. Mitochondrial low Km aldehyde dehydrogenase inhibition and implications for its alcohol-deterrent action.

Biochemical pharmacology, 1998
S-Methyl N,N-diethylthiolcarbamate sulfoxide (DETC-MeSO) and sulfone (DETC-MeSO2) both inhibit rat liver low Km aldehyde dehydrogenase (ALDH2) in vitro and in vivo (Nagendra et al., Biochem Pharmacol 47: 1465-1467, 1994). DETC-MeSO has been shown to be a metabolite of disulfiram, but DETC-MeSO2 has not.
N S, Ningaraj, J V, Schloss, T D, Williams, M D, Faiman   +3 more
openaire   +2 more sources

[Activity of enzymes of ethanol metabolism as a test in evaluating the effectiveness of sensitizing alcohol deterrents].

Ukrainskii biokhimicheskii zhurnal (1978), 1987
A procedure is developed for determination of the efficiency of the antialcoholic drugs' action on the system of ethanol oxidation in vitro: alcohol dehydrogenase by the direct and reverse reactions and aldehyde dehydrogenase of subcellular fractions of the rat liver.
G A, Pkhakadze, K L, Konoplitskaia, T N, Pozniakova, T I, Mnyshenko, V P, Nazaretian   +4 more
openaire   +1 more source

Prodrugs of cyanamide as (long-acting) alcohol deterrent agents

Biochemical Pharmacology, 1986
H T, Nagasawa, C H, Kwon, E G, DeMaster, F N, Shirota   +3 more
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[Aldehyde dehydrogenases in the rat liver after implantation of a prolonged-action preparation of an alcohol deterrent].

Voprosy meditsinskoi khimii, 1985
Activity of aldehyde dehydrogenase isoenzymes was studied in rat liver mitochondria and microsomes after implantation of the new antialcohol drug of the long-term effect synthesized on the basis of disulphirame. Disulphirame, both in vivo and in vitro was shown to inhibit dissimilarly these isoenzymes.
K L, Konoplitskaia, T N, Pozniakova, M V, Grigor'eva   +2 more
openaire   +1 more source

Use of Intermediaries in DWI Deterrence. Volume 3, Dram Shop Acts, Common Law Liability and State Alcoholic Beverage Control (ABC) Enforcement as Potential DWI Countermeasures

1983
4, 22 p.
Wagner, Marvin H., Cozzens, William A., National Capitol Systems, Inc.   +2 more
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In Vitro Abuse-Deterrent Performance of a QbD-Optimized Metformin HCl Extended-Release Matrix Tablet: Resistance to Crushing, Extraction, Syringeability and Alcohol-Induced Dose Dumping

International Journal of Drug Delivery Technology
Objective: To characterize the in vitro abuse-deterrent performance of a QbD-optimized extended-release (ER) matrix tablet containing metformin HCl as a non-opioid model drug, focusing on crushing behaviour, particle size distribution, extraction, Syringeability/injectability and alcohol-induced dose dumping.
Amul Mishra, Varinder Kumar
openaire   +1 more source

Travel deterrents to regional destinations

Journal of Retailing and Consumer Services, 2021
Catherine Prentice, Aaron Hsiao
exaly  

26667 Symmetrical intertriginous and flexural exanthema (baboon syndrome) induced by alcohol deterrent drug

Journal of the American Academy of Dermatology, 2021
Alin Laurentiu Tatu, Diana Sabina Radaschin, Florin Ciprian Bujoreanu, Elena Niculet, Alin Laurentiu Tatu   +4 more
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Citrated Calcium Carbimide/Alcohol Reaction—its Severity and Effectiveness as a Deterrent

British Journal of Addiction to Alcohol & Other Drugs, 1971
C S, Mellor, A C, Sims
openaire   +2 more sources