Results 101 to 110 of about 205,440 (310)
Advanced Science, EarlyView.This study identifies that REGγ is elevated in obese adipose tissue. REGγ modulates WAT browning via ubiquitin‐independent ACADM/KLF15–UCP1 degradation. Overactivation of the NRF2–REGγ axis facilitates adipose tissue function to cause obesity. Inhibition of REGγ in the iWAT alleviates HFD‐induced obesity.
Hui Chen +15 more
wiley +1 more source
Difficulties with Questions on Usual Drinking and the Measurement of Alcohol Consumption [PDF]
, 1998 Deborah S. Hasin, Kenneth M. Carpenter
openalex +1 more source
Advanced Science, EarlyView.This study analyzes 398 432 participants, identifying four distinct metabolic‐inflammatory subtypes. These subtypes show a significant association with digestive disease risk. Cluster‐associated metabolite signatures partially explain this link. Machine learning models using these metabolites accurately predict risk for ten digestive diseases. Key risk
Zhenhe Jin +10 more
wiley +1 more source
CO-MORBID DEPRESSION AND DRINKING OUTCOME IN THOSE WITH ALCOHOL DEPENDENCE [PDF]
, 1998 Kate Davidson, Ivy M. Blackburn
openalex +1 more source
Advanced Science, EarlyView.In this study, it is discovered that pathological accumulation of Runx2+ Schwann cell clusters during axonal regeneration is a key factor impairing nerve repair in aging. This pathology is associated with dysregulation of stress granule homeostasis.
Peilin Wang +10 more
wiley +1 more source
Advanced Science, EarlyView.Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao +11 more
wiley +1 more source
Effects of Injection of Analgetics and Alcohol Drinking on Values of Electric Flicker
, 1957 Kiichiro Suzuki +3 more
openalex +2 more sources
SPECIAL ARTICLE ESBRA 1997 AWARD LECTURE: RELATIONSHIP BETWEEN EXCESSIVE ALCOHOL DRINKING AND VIRAL INFECTIONS [PDF]
, 1998 Bertrand Nalpas +5 more
openalex +1 more source
Advanced Science, EarlyView.Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Lixiao Zhou +15 more
wiley +1 more source