Results 181 to 190 of about 623,469 (364)

Nine‐Year Follow‐Up After M‐TEER for Secondary Mitral Regurgitation in a Patient With Cardiogenic Shock

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter edge‐to‐edge repair (TEER) has become an established therapeutic option for patients with severe secondary mitral regurgitation (SMR). While randomized trials and registry data have reported outcomes up to 5 years, longer follow‐up data remain scarce.
Tobias Reithmayer   +9 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

Aggression and repeated alcohol drinking-in-the-dark: dissecting subtypes in outbred mice. [PDF]

open access: yesPsychopharmacology (Berl)
Frier MD   +5 more
europepmc   +1 more source

Effect of Chronic Noncommunicable Diseases Multimorbidity on Functional Disability in Older Adults in Ireland: Evidence From the 2019 Irish Health Survey

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Prevalence (%) of different morbidities in the Irish Health Survey 2019. Note: Asthma, bronchitis (chronic bronchitis or chronic obstructive pulmonary disease or emphysema), heart attack (heart attack or chronic consequences of heart attack), CHD (coronary heart disease or angina pectoris), HBP (high blood pressure), stroke (stroke or the chronic ...
Alwalid Ali, Santosh Sharma
wiley   +1 more source

Metabolic dysfunction‐associated fatty liver disease and excessive alcohol consumption are both independent risk factors for mortality

open access: yesHepatology, EarlyView., 2022
Visualisation of the study desgin, main results and key findings. Abstract Background and Aims MAFLD often cooccurs with excessive alcohol consumption, while its prognostic value in this group remains unclear. We aimed to study the mortality risk of MAFLD in relation to excessive alcohol consumption and its potential interactions.
Laurens A. van Kleef   +2 more
wiley   +1 more source

Tirzepatide reduces alcohol drinking and relapse-like behaviours in rodents. [PDF]

open access: yesEBioMedicine
Edvardsson CE   +13 more
europepmc   +1 more source

The Wonders of Vanilla: Celebrating the 150th Anniversary of Synthetic Vanillin

open access: yesChemFoodChem, EarlyView.
The year 2024 marked the 150th anniversary of the first commercial production of vanillin, one of the world's most cherished flavor ingredients. This review traces vanilla's history from Mesoamerica to modern production methods, examines its composition, the discovery of vanillin and Haarmann's early synthesis compared to modern methods, and highlights
Elisabetta Brenna   +2 more
wiley   +1 more source

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

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