Results 191 to 200 of about 862,088 (250)

Cardiometabolic Health and Risk of Breast Cancer Subtypes Among US Black Women

International Journal of Cancer, EarlyView.
ABSTRACT In the United States (US), cardiometabolic conditions and aggressive breast cancers are both more common among Black women than White women. Using data from 57,453 participants in the Black Women's Health Study (BWHS), we prospectively evaluated associations of body mass index (BMI), Type 2 diabetes, hypertension, and hypercholesterolemia with
Yifei Shan, Sarah M. Rothbard, Lynn Rosenberg, Julie R. Palmer, Mollie E. Barnard   +4 more
wiley   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

Interdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong, Long Chen, Yiting Zhao, Xiaohe Wang, Qiang Yuan, Xiaofeng Fang, Liuyi Li, Yinbo Xu, Shumei Jiang, Guangwen Xu, Ke Meng, Delong Wang, Kangli Cao, Jianlong Sheng, Liling Guo, Shichun Shen   +15 more
wiley   +1 more source

Revisiting Maternal and Paternal Parenting Styles: Differentiating Latent Profiles and Associations With Psychosocial Outcomes of Chinese Adolescents in a National Sample of Parent‐Child Dyads

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Parent‐child interactions constitute a critical developmental context for the psychosocial adjustment of adolescents. This study aimed to differentiate parenting styles and examine their domain‐specific effects on later adolescent outcomes, using a culturally sensitive, person‐centered approach.
Yuhang Cheng, Randolph C. H. Chan
wiley   +1 more source

Acquiring Knowledge About Adolescents’ Activities: Muslim Mothers and Their Daughters and Sons

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Drawing on social cognitive domain theory, this study investigated how Muslim mothers in the United States acquired knowledge regarding their adolescent children's activities. Despite the importance of parental monitoring in adolescent development, research remains limited regarding how cultural and religious contexts shape these ...
Christopher Daddis, Aaron Metzger, Ayah Said   +2 more
wiley   +1 more source

Reframing Clinical Supervision in Addiction Treatment: A Blended Developmental, Competency‐Based, and Trauma‐Informed Framework

Journal of Addictions &Offender Counseling, EarlyView.
ABSTRACT This article examines the current landscape of clinical supervision in addiction treatment and proposes a blended supervision framework integrating developmental, competency‐based, and trauma‐informed approaches. The article explores how this integrated model can enhance clinical competence, ethical practice, and counselor resilience while ...
Cyrus Williams, Robert Loper, Rebecca Belton   +2 more
wiley   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Rethinking ethanol separation in continuous spirit production from a process intensification perspective

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Continuous neutral‐alcohol and food‐grade ethanol production is an energy‐intensive process in which distillation and rectification alone account for 50–85% of total plant energy use. While significant advances in separation technology have emerged over the past two decades, the spirits industry continues to rely predominantly on multi‐effect ...
Anton A Kiss
wiley   +1 more source

Decision‐making and risk‐taking as predictors of health risk behaviors in the Millennium Cohort Study

JCPP Advances, EarlyView.
Abstract Background Facets of decision‐making and risk‐taking are implicated in adolescent health risk behaviors; however, whether they may lead to adolescent engagement in substance use, gambling, and self‐harm is unknown. Methods We used the Millennium Cohort Study to test whether a task‐based measure of decision‐making and risk‐taking predicts ...
Nicole G. Hammond, Georgia Condran, Elise E. DeVito, Marie‐Claude Geoffroy, Ian Colman   +4 more
wiley   +1 more source